Patents by Inventor MARGARET W. KAYO

MARGARET W. KAYO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of rapamycin derivatives using temperature induced phase separation
    Patent number: 11780850
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: October 10, 2023
    Assignee: Biosensors International Group, Ltd.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of Rapamycin Derivatives Using Temperature Induced Phase Separation
    Publication number: 20220024947
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Application
    Filed: June 28, 2021
    Publication date: January 27, 2022
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of rapamycin derivatives using temperature induced phase separation
    Patent number: 11046711
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: June 29, 2021
    Assignee: Biosensors International Group, Ltd.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • PURIFICATION OF RAPAMYCIN DERIVATIVES USING TEMPERATURE INDUCED PHASE SEPARATION
    Publication number: 20200270272
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Application
    Filed: March 2, 2020
    Publication date: August 27, 2020
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, LeelaKrishna Kondaveti, Aniruddh Singh
  • Purification of rapamycin derivatives using temperature induced phase separation
    Patent number: 10597406
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: March 24, 2020
    Assignee: Biosensors International Group, Ltd.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of Rapamycin Derivatives Using Temperature Induced Phase Separation
    Publication number: 20190256527
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Application
    Filed: December 18, 2018
    Publication date: August 22, 2019
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of rapamycin derivatives using temperature induced phase separation
    Patent number: 10202402
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: February 12, 2019
    Assignee: Biosensors International Group, Ltd.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of Rapamycin Derivatives Using Temperature Induced Phase Separation
    Publication number: 20170334928
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Application
    Filed: February 2, 2017
    Publication date: November 23, 2017
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Purification of rapamycin derivatives using temperature induced phase separation
    Patent number: 9598439
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: March 21, 2017
    Assignee: BIOSENSORS INTERNATIONAL GROUP, LTD.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik, Leelakrishna Kondaveti, Aniruddh Singh
  • Low temperature synthesis of rapamycin derivatives
    Patent number: 9434744
    Abstract: The present invention provides improved processes for obtaining rapamycin derivatives including Biolimus A9.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: September 6, 2016
    Assignee: Biosensors International Group, Ltd.
    Inventors: Margaret W. Kayo, Richard S. Fornicola, Ivan Kovacik
  • PURIFICATION OF RAPAMYCIN DERIVATIVES USING TEMPERATURE INDUCED PHASE SEPARATION
    Publication number: 20160002262
    Abstract: The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.
    Type: Application
    Filed: September 14, 2015
    Publication date: January 7, 2016
    Inventors: MARGARET W. KAYO, RICHARD S. FORNICOLA, IVAN KOVACIK, LEELAKRISHNA KONDAVETI, ANIRUDDH SINGH
  • LOW TEMPERATURE SYNTHESIS OF RAPAMYCIN DERIVATIVES
    Publication number: 20150322086
    Abstract: The present invention provides improved processes for obtaining rapamycin derivatives including Biolimus A9.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: MARGARET W. KAYO, RICHARD S. FORNICOLA, IVAN KOVACIK