Patents by Inventor Margaret Westfall

Margaret Westfall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RFamide-related peptides and methods thereof
    Patent number: 9527889
    Abstract: Provided herein methods and compositions directed to RFRP-1 polypeptides for modulating cardiac contractile function, for preventing and/or treating cardiac disorders.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: December 27, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Ruthann Nichols, Margaret Westfall
  • RFAMIDE-RELATED PEPTIDES AND METHODS THEREOF
    Publication number: 20150183829
    Abstract: Provided herein methods and compositions directed to RFRP-1 polypeptides for modulating cardiac contractile function, for preventing and/or treating cardiac disorders.
    Type: Application
    Filed: December 24, 2014
    Publication date: July 2, 2015
    Inventors: RUTHANN NICHOLS, MARGARET WESTFALL
  • Compositions and methods for regulating cardiac performance
    Patent number: 8557969
    Abstract: The present invention relates to cardiac performance, in particular to regulating cardiac performance via recombinant troponin I (TnI) protein and nucleic acids encoding recombinant TnI. The present invention provides nucleic acids encoding gain of function TnI proteins (e.g., cTnlA164H), vectors containing such nucleic acids, host cells containing such vectors, transgenic animals carrying a gain of function TnI protein (e.g., a cTnlA164H transgene), and therapeutic agents (e.g., comprising recombinant TnI, TnI analogues, synthetic TnI, or the like) or agents for gene therapy of heart failure or disease for research and therapeutic uses.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: October 15, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: Joseph Metzger, Margaret Westfall, Sharlene Day
  • RFamide-Related Peptides and Methods Thereof
    Publication number: 20130116184
    Abstract: Provided herein methods and compositions directed to RFRP-1 polypeptides for modulating cardiac contractile function, for preventing and/or treating cardiac disorders.
    Type: Application
    Filed: March 31, 2011
    Publication date: May 9, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Ruthann Nichols, Margaret Westfall
  • Compositions And Methods For Regulating Cardiac Performance
    Publication number: 20080263691
    Abstract: The present invention relates to cardiac performance, in particular to regulating cardiac performance via recombinant troponin I (TnI) protein and nucleic acids encoding recombinant TnI. The present invention provides nucleic acids encoding gain of function TnI proteins (e.g., cTnlA164H), vectors containing such nucleic acids, host cells containing such vectors, transgenic animals carrying a gain of function TnI protein (e.g., a cTnlA164H transgene), and therapeutic agents (e.g., comprising recombinant TnI, TnI analogues, synthetic TnI, or the like) or agents for gene therapy of heart failure or disease for research and therapeutic uses.
    Type: Application
    Filed: December 1, 2005
    Publication date: October 23, 2008
    Inventors: Joseph Metzger, Margaret Westfall, Sharlene Day