Patents by Inventor Margarita L. Dubocovich

Margarita L. Dubocovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF
    Publication number: 20230052740
    Abstract: Disclosed herein are, inter alia, compounds modulating MT1 and MT2 receptors' activity and methods of use thereof for treating MT1 and MT2 receptor-related conditions.
    Type: Application
    Filed: August 27, 2020
    Publication date: February 16, 2023
    Inventors: Brian K. Shoichet, Reed M. Stein, Margarita L. Dubocovich, Grant C. Glatfelter, Bryan L. Roth, Hye Jin Kang
  • 2-aryl substituted N-acetyltryptamines and process of preparing such
    Patent number: 5283343
    Abstract: This invention relates to novel melatonin derivatives, such as 2-aryl substituted N-acetyltryptamines, having pharmacological activity, e.g., melatonin antagonist activity, and methods for the synthesis thereof.
    Type: Grant
    Filed: June 18, 1991
    Date of Patent: February 1, 1994
    Assignee: Whitby Research, Inc.
    Inventors: Margarita L. Dubocovich, Vithal J. Rajadhyaksha, James V. Peck, Atef A. Helmy
  • Substituted 2-amidotetralins as melatonin agonists and antagonists
    Patent number: 5151446
    Abstract: The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising such compounds; and to methods for using these compounds as therapeutic and diagnostic reagents.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: September 29, 1992
    Assignee: Northwestern University
    Inventors: Alan S. Horn, deceased, Margarita L. Dubocovich
  • Antidepressant agents
    Patent number: 5093352
    Abstract: 2-aryl substituted N-acetyl tryptamines are utilized as antidepressant agents.
    Type: Grant
    Filed: May 16, 1990
    Date of Patent: March 3, 1992
    Assignee: Whitby Research, Inc.
    Inventor: Margarita L. Dubocovich
  • Substituted 2-amidotetralins as melatonin agonists and antagonists
    Patent number: 5071875
    Abstract: The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising such compounds; and to methods for using these compounds as therapeutic and diagnostic reagents.
    Type: Grant
    Filed: September 25, 1989
    Date of Patent: December 10, 1991
    Assignee: Northwestern University
    Inventors: Alan S. Horn, Margarita L. Dubocovich