Patents by Inventor Margarita Lib

Margarita Lib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunocapture-based measurements of mammalian pyruvate dehydrogenase complex
    Publication number: 20050239143
    Abstract: The present invention is based on the discovery that an antibody specific for PDH complex can be used to immunoprecitate PDH complex from the patient sample in an active state. Therefore the anti-PDH complex specific antibody can be used to determine the amount of and/or active state of PDH in a patient sample. The invention immunoassay methods for determining the amount and/or active state of PDH complex present in a patient sample are useful for screening to identify individuals having symptoms indicating malfunction of PDH complex. For example, the invention methods can be used to screen individuals for symptoms of onset of the diabetic state, such as insulitis, and for diagnosing late onset diseases, such as diabetes, Alzheimer's and the like.
    Type: Application
    Filed: August 29, 2003
    Publication date: October 27, 2005
    Inventors: Roderick Capaldi, Margarita Lib, Michael Marusich