Patents by Inventor Margherita Sosio

Margherita Sosio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lantipeptide
    Patent number: 10487124
    Abstract: The present invention concerns novel lantipeptide (lanthionine-containing peptide) compounds having general formula (I), a process for their preparation, the key intermediates in said processes, their pharmaceutical acceptable salts and pharmaceutical compositions containing them, as well as their use in the treatment of pain.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: November 26, 2019
    Assignees: NAICONS S.r.l., FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Marianna Iorio, Sonia Maffioli, Paolo Monciardini, Margherita Sosio, Stefano Donadio, Rosalia Bertorelli, Oscar Sasso, Angelo Reggiani
  • NOVEL LANTIPEPTIDE
    Publication number: 20150291670
    Abstract: The present invention concerns novel lantipeptide (lanthionine-containing peptide) compounds having general formula (I), a process for their preparation, the key intermediates in said processes, their pharmaceutical acceptable salts and pharmaceutical compositions containing them, as well as their use in the treatment of pain.
    Type: Application
    Filed: July 12, 2012
    Publication date: October 15, 2015
    Inventors: Marianna Iorio, Sonia Maffioli, Paolo Monciardini, Margherita Sosio, Stefano Donadio, Rosalia Bertorelli, Oscar Sasso, Angelo Reggiani
  • Genes and Proteins for the Biosynthesis of the Lantibiotic 107891
    Publication number: 20140038297
    Abstract: The Invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 6, 2014
    Applicant: Sentinella Pharmaceuticals, Inc.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mecorillo
  • Genes and proteins for the biosynthesis of the lantibiotic 107891
    Patent number: 8609367
    Abstract: The invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: December 17, 2013
    Assignee: Sentinella Pharmaceuticals, Inc.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mercorillo
  • GENES AND PROTEINS FOR THE BIOSYNTHESIS OF THE LANTIBIOTIC 107891
    Publication number: 20120015418
    Abstract: The invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Application
    Filed: August 3, 2007
    Publication date: January 19, 2012
    Applicant: SENTINELLA PHARMACEUTICALS ,INC.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mercorillo
  • Genes and Proteins For the Biosynthesis of the Glycopeptide Antibiotic A40926
    Publication number: 20080145892
    Abstract: The present invention relates to the field of antibiotics, and more specifically to the isolation of nucleic acid molecules that code for the biosynthetic pathway of the glycopeptide antibiotic A40926. Disclosed are the functions of the gene products involved in A40926 production. The present invention provides biosynthetic genes that code for A40926 production, the encoded polypeptides, the recombinant vectors comprising the nucleic acid sequences that encode said polypeptides, the host cells transformed with said vectors and methods for producing glycopeptide antibiotics using said transformed host cells, including methods for producing A40926, a precursor thereof, a derivative thereof or a modified glycopeptide different from A 40926 or a precursor thereof.
    Type: Application
    Filed: October 15, 2003
    Publication date: June 19, 2008
    Applicant: Pfizer
    Inventors: Stefano Donadio, Margherita Sosio, Fabrizio Beltrametti