Patents by Inventor Margit Hiesinger

Margit Hiesinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10745686
    Abstract: The present invention provides method for isolating DNA molecules having a size above a certain cut-off value from a DNA containing sample, comprising a) contacting the sample with a binding buffer which comprises a chaotropic agent and a buffering agent to provide a binding mixture and binding DNA molecules having a size above the cut-off value to a binding matrix which has a silicon containing surface, wherein the cut-off value is determined by the pH value of the binding mixture; b) separating the bound DNA from the remaining sample; c) optionally washing the bound DNA; and d) optionally eluting the bound DNA from the binding matrix. Said method allows the size selective purification of DNA molecules.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: August 18, 2020
    Assignee: QIAGEN GmBH
    Inventors: Tanya Sperling, Nicola Scholle, Thorsten Singer, Margit Hiesinger
  • Patent number: 10094749
    Abstract: The present invention refers to a device, comprising a hollow body having at least one open end and at least one barrier inside or at the end of the hollow body, which is non-permeable for liquids and solids under ambience conditions, however, becomes liquid-permeable by applying an external force like pressure, drag force or driving power to said barrier, the use of such a device for collection, storage, treatment or isolation of a biomolecule or biomolecules containing samples, a method for preparation of said device and a method for isolation or purification of any biomolecules using said device.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: October 9, 2018
    Assignee: QIAGEN GmbH
    Inventors: Margit Hiesinger, Vera Holländer, Markus Müller, Karin Schulte, Andre Schrader
  • Publication number: 20160024490
    Abstract: The present invention provides method for isolating DNA molecules having a size above a certain cut-off value from a DNA containing sample, comprising a) contacting the sample with a binding buffer which comprises a chaotropic agent and a buffering agent to provide a binding mixture and binding DNA molecules having a size above the cut-off value to a binding matrix which has a silicon containing surface, wherein the cut-off value is determined by the pH value of the binding mixture; b) separating the bound DNA from the remaining sample; c) optionally washing the bound DNA; and d) optionally eluting the bound DNA from the binding matrix. Said method allows the size selective purification of DNA molecules.
    Type: Application
    Filed: February 7, 2014
    Publication date: January 28, 2016
    Inventors: Tanya SPERLING, Nicola SCHOLLE, Thorsten SINGER, Margit HIESINGER
  • Publication number: 20140134718
    Abstract: The present invention relates to a device for rapid isolation of target molecules from cell lysates and other liquid mixtures comprising particulate material, a method for isolating the target molecules, in particular nucleic acids, using said device and a kit for carrying out said method comprising said device.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 15, 2014
    Applicant: QIAGEN GmbH
    Inventors: Margit Hiesinger, Karin Schulte
  • Publication number: 20130189726
    Abstract: The present invention pertains to a biotechnological method for preparing and/or processing a biological sample, in particular for isolating at least one target biomolecule therefrom, which characterised in that at least one malodour counteractant is used for preventing, reducing, masking and/or suppressing malodour and/or malodour formation during the preparation and/or processing of said biological sample.
    Type: Application
    Filed: September 26, 2011
    Publication date: July 25, 2013
    Applicant: QIAGEN GmbH
    Inventors: Margit Hiesinger, Markus Mueller
  • Publication number: 20130112622
    Abstract: The present invention refers to a device, comprising a hollow body having at least one open end and at least one barrier inside of the hollow body, which is non-permeable for liquids and solids under ambience conditions, however, becomes liquid-permeable by applying an external force like pressure, drag force or driving power to said barrier, wherein said barrier is spaced from at least one open end of the hollow body, the use of such a device for processing of a liquid sample, a method for preparation of said device and a method for isolation or purification of any biomolecules using said device.
    Type: Application
    Filed: July 13, 2011
    Publication date: May 9, 2013
    Applicant: QIAGEN GMBH
    Inventors: Markus Müller, Margit Hiesinger
  • Publication number: 20130105393
    Abstract: The present invention refers to a device, comprising a hollow body having at least one open end and at least one barrier inside or at the end of the hollow body, which is non-permeable for liquids and solids under ambience conditions, however, becomes liquid-permeable by applying an external force like pressure, drag force or driving power to said barrier, the use of such a device for collection, storage, treatment or isolation of a biomolecule or biomolecules containing samples, a method for preparation of said device and a method for isolation or purification of any biomolecules using said device.
    Type: Application
    Filed: July 13, 2011
    Publication date: May 2, 2013
    Applicant: QIAGEN GMBH
    Inventors: Margit Hiesinger, Vera Holländer, Markus Müller, Karin Schulte, Andre Schrader