Patents by Inventor Margret Oethinger

Margret Oethinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF REDUCING MICROBIAL RESISTANCE TO DRUGS
    Publication number: 20110301127
    Abstract: The instant methods and compositions represent an advance in controlling drug resistance in microbes. AcrAB-like efflux pumps have been found to control resistance to drugs, even in highly resistant microbes. Accordingly, methods of treating infection, methods of screening for inhibitors of AcrAB-like efflux pumps, and methods of enhancing antimicrobial activity of drugs are provided. Pharmaceutical composition comprising an inhibitor of an AcrAB-like efflux pump and an antimicrobial agent are also provided.
    Type: Application
    Filed: August 16, 2011
    Publication date: December 8, 2011
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: Margret OETHINGER, Stuart B. LEVY
  • Methods of screening for compounds that reduce microbial resistance to fluoroquinolones
    Patent number: 8012711
    Abstract: The instant methods and compositions represent an advance in controlling drug resistance in microbes. AcrAB-like efflux pumps have been found to control resistance to drugs, even in highly resistant microbes. Accordingly, methods of treating infection, methods of screening for inhibitors of AcrAB-like efflux pumps, and methods of enhancing antimicrobial activity of drugs are provided. Pharmaceutical composition comprising an inhibitor of an AcrAB-like efflux pump and an antimicrobial agent are also provided.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: September 6, 2011
    Assignee: Trustees of Tufts College
    Inventors: Margret Oethinger, Stuart B. Levy
  • Methods of reducing microbial resistance to drugs
    Publication number: 20050261165
    Abstract: The instant methods and compositions represent an advance in controlling drug resistance in microbes. AcrAB-like efflux pumps have been found to control resistance to drugs, even in highly resistant microbes. Accordingly, methods of treating infection, methods of screening for inhibitors of AcrAB-like efflux pumps, and methods of enhancing antimicrobial activity of drugs are provided. Pharmaceutical composition comprising an inhibitor of an AcrAB-like efflux pump and an antimicrobial agent are also provided.
    Type: Application
    Filed: July 28, 2003
    Publication date: November 24, 2005
    Applicant: Trustees of Tufts College
    Inventors: Margret Oethinger, Stuart Levy