Patents by Inventor Marguerita S. L. Lim-Wilby

Marguerita S. L. Lim-Wilby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors
    Patent number: 6034215
    Abstract: The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: March 7, 2000
    Assignee: Corvas International, Inc.
    Inventors: Joseph Edward Semple, Robert John Ardecky, Ruth Foelsche Nutt, William Charles Ripka, David C. Rowley, Marguerita S. L. Lim-Wilby, Terence Kevin Brunck
  • Aromatic heterocyclic derivatives as enzyme inhibitors
    Patent number: 6011158
    Abstract: The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
    Type: Grant
    Filed: June 7, 1996
    Date of Patent: January 4, 2000
    Assignee: Corvas International, Inc.
    Inventors: Susan Yoshiko Tamura, Joseph Edward Semple, William Charles Ripka, Robert John Ardecky, Yu Ge, Stephen H. Carpenter, Terence K. Brunck, Marguerita S. L. Lim-Wilby, Ruth F. Nutt, Matthew M. Abelman
  • Aromatic hetherocyclic derivatives as enzyme inhibitors
    Patent number: 6008351
    Abstract: The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: December 28, 1999
    Assignee: Corvas International, Inc.
    Inventors: Susan Yoshiko Tamura, Joseph Edward Semple, William Charles Ripka, Robert John Ardecky, Yu Ge, Stephen H. Carpenter, Terence K. Brunck, Marguerita S. L. Lim-Wilby, Ruth F. Nutt, Matthew M. Abelman
  • 3-amino-2-oxo-1-piperidineacetic derivatives as enzyme inhibitors
    Patent number: 5703208
    Abstract: The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 30, 1997
    Assignee: Corvas International, Inc.
    Inventors: Joseph Edward Semple, Robert John Ardecky, Ruth Foelsche Nutt, William Charles Ripka, David C. Rowley, Marguerita S. L. Lim-Wilby, Terence Kevin Brunck