Patents by Inventor Marguerite A. Sognier

Marguerite A. Sognier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10966809
    Abstract: A method and a device for treating dental caries using microwave energy applied directly to teeth at frequencies that are lethal to the bacteria in caries, without being destructive to tooth tissues. The method and a device will have a significant economic and health impact, leading to a reduction in traditional surgical interventions, as well by improving access to care for those with health disparities.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: April 6, 2021
    Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
    Inventors: Ivan Stangel, Marguerite A. Sognier, George D. Arndt, Diane L. Byerly, John Dusl
  • Patent number: 9328000
    Abstract: A system for decontaminating a medium. The system can include a medium having one or more contaminants disposed therein. The contaminants can be or include bacteria, fungi, parasites, viruses, and combinations thereof. A microwave energy radiation device can be positioned proximate the medium. The microwave energy radiation device can be adapted to generate a signal having a frequency from about 10 GHz to about 100 GHz. The signal can be adapted to kill one or more of the contaminants disposed within the medium while increasing a temperature of the medium by less than about 10° C.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: May 3, 2016
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: G. Dickey Arndt, Diane Byerly, Marguerite Sognier, John Dusl
  • Patent number: 9242874
    Abstract: A system for decontaminating a medium. The system can include a medium having one or more contaminants disposed therein. The contaminants can be or include bacteria, fungi, parasites, viruses, and combinations thereof. A microwave energy radiation device can be positioned proximate the medium. The microwave energy radiation device can be adapted to generate a signal having a frequency from about 10 GHz to about 100 GHz. The signal can be adapted to kill one or more of the contaminants disposed within the medium while increasing a temperature of the medium by less than about 10° C.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: January 26, 2016
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: G. Dickey Arndt, Diane Byerly, Marguerite Sognier, John Dusl
  • Patent number: 9243223
    Abstract: A model of tissue is produced by steps comprising seeding cells at a selected concentration on a support to form a cell spot, incubating the cells to allow the cells to partially attach, rinsing the cells to remove any cells that have not partially attached, adding culture medium to enable the cells to proliferate at a periphery of the cell spot and to differentiate toward a center of the cell spot, and further incubating the cells to form the tissue. The cells may be C2C12 cells or other subclones of the C2 cell line, H9c2(2-1) cells, L6 cells, L8 cells, QM7 cells, Sol8 cells, G-7 cells, G-8 cells, other myoblast cells, cells from other tissues, or stem cells. The selected concentration is in a range from about 1×105 cells/ml to about 1×106 cells/ml. The tissue formed may be a muscle tissue or other tissue depending on the cells seeded.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: January 26, 2016
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Michele L. Marquette, Marguerite A. Sognier
  • Publication number: 20150374471
    Abstract: A method and a device for treating dental caries using microwave energy applied directly to teeth at frequencies that are lethal to the bacteria in caries, without being destructive to tooth tissues. The method and a device will have a significant economic and health impact, leading to a reduction in traditional surgical interventions, as well by improving access to care for those with health disparities.
    Type: Application
    Filed: February 3, 2014
    Publication date: December 31, 2015
    Inventors: Ivan Stangel, Marguerite A. Sognier, George D. Arndt, Diane L. Byerly, John Dusl
  • Publication number: 20140256036
    Abstract: A model of tissue is produced by steps comprising seeding cells at a selected concentration on a support to form a cell spot, incubating the cells to allow the cells to partially attach, rinsing the cells to remove any cells that have not partially attached, adding culture medium to enable the cells to proliferate at a periphery of the cell spot and to differentiate toward a center of the cell spot, and further incubating the cells to form the tissue. The cells may be C2C12 cells or other subclones of the C2 cell line, H9c2(2-1) cells, L6 cells, L8 cells, QM7 cells, Sol8 cells, G-7 cells, G-8 cells, other myoblast cells, cells from other tissues, or stem cells. The selected concentration is in a range from about 1×105 cells/ml to about 1×106 cells/ml.
    Type: Application
    Filed: May 20, 2014
    Publication date: September 11, 2014
    Inventors: Michele L. Marquette, Marguerite A. Sognier
  • Patent number: 8735116
    Abstract: A method for making a tissue includes seeding cells at a selected concentration on a support to form a cell spot, incubating the cells to allow the cells to partially attach, rinsing the cells to remove any unattached cells, adding culture medium to enable the cells to proliferate at a periphery of the cell spot and to differentiate toward a center of the cell spot, and further incubating the cells to form the tissue. The cells may be C2C12 cells or other subclones of the C2 cell line, H9c2(2-1) cells, L6 cells, L8 cells, QM7 cells, Sol8 cells, G-7 cells, G-8 cells, other myoblast cells, cells from other tissues, or stem cells. The selected concentration is in a range from about 1×105 cells/ml to about 1×106 cells/ml. The tissue formed may be a skeletal muscle tissue, a cardiac muscle tissue, nerve tissue, or a bone tissue.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: May 27, 2014
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Michele L. Marquette, Marguerite A. Sognier
  • Patent number: 8388613
    Abstract: Methods and apparatus for joining biological tissue together are provided. In at least one specific embodiment, a method for joining biological tissue together can include applying a biological solder on a wound. A barrier layer can be disposed on the biological solder. An antenna can be located in proximate spatial relationship to the barrier layer. An impedance of the antenna can be matched to an impedance of the wound. Microwaves from a signal generator can be transmitted through the antenna to weld two or more biological tissue pieces of the wound together. A power of the microwaves can be adjusted by a control circuit disposed between the antenna and the signal generator. The heating profile within the tissue may be adjusted and controlled by the placement of metallic microspheres in or around the wound.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: March 5, 2013
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: G. Dickey Arndt, Phong H. Ngo, Chau T. Phan, Diane L. Byerly, John R. Dusl, Marguerite A. Sognier, James R. Carl
  • Publication number: 20120064596
    Abstract: A method for making a tissue includes seeding cells at a selected concentration on a support to form a cell spot, incubating the cells to allow the cells to partially attach, rinsing the cells to remove any unattached cells, adding culture medium to enable the cells to proliferate at a periphery of the cell spot and to differentiate toward a center of the cell spot, and further incubating the cells to form the tissue. The cells may be C2C12 cells or other subclones of the C2 cell line, H9c2(2-1) cells, L6 cells, L8 cells, QM7 cells, Sol8 cells, G-7 cells, G-8 cells, other myoblast cells, cells from other tissues, or stem cells. The selected concentration is in a range from about 1×105 cells/ml to about 1×106 cells/ml. The tissue formed may be a skeletal muscle tissue, a cardiac muscle tissue, nerve tissue, or a bone tissue.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 15, 2012
    Inventors: Michele L. Marquette, Marguerite A. Sognier