Patents by Inventor Mari ISOMI

Mari ISOMI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING CARDIAC PRECURSOR CELL AND MYOCARDIAL CELL FROM PLURIPOTENT STEM CELL
    Publication number: 20190078053
    Abstract: Provided is a method of inducing cardiac progenitor cells or cardiomyocytes from pluripotent stem cells. The present invention provides a method for producing cardiac progenitor cells from pluripotent stem cells, comprising expressing Tbx6 in the pluripotent stem cells. Moreover, the present invention provides a method for producing cardiomyocytes from pluripotent stem cells, comprising: a step of inducing cardiac progenitor cells from pluripotent stem cells, comprising expressing a Tbx6 gene in the pluripotent stem cells; and a step of inducing cardiomyocytes from the cardiac progenitor cells induced in the above step, comprising suppressing the expression of the Tbx6 gene.
    Type: Application
    Filed: March 7, 2017
    Publication date: March 14, 2019
    Applicants: Keio University, National Institute of Advanced Industrial Science and Technology
    Inventors: Masaki IEDA, Taketaro SADAHIRO, Mari ISOMI, Naoki GOSHIMA
  • METHOD FOR DIRECTLY PRODUCING CARDIAC PRECURSOR CELL OR MYOCARDIAL CELL FROM FIBROBLAST
    Publication number: 20190071641
    Abstract: Provided is a method of inducing cardiac progenitor cells or cardiomyocytes from fibroblasts. The present invention provides a method for producing cardiac progenitor cells, comprising introducing one cardiac reprogramming factor into fibroblasts, or a method for producing cardiomyocytes, comprising introducing three cardiac reprogramming factors into fibroblasts.
    Type: Application
    Filed: March 7, 2017
    Publication date: March 7, 2019
    Applicants: Keio University, National Institute of Advanced Industrial Science and Technology
    Inventors: Masaki IEDA, Taketaro SADAHIRO, Mari ISOMI, Naoki GOSHIMA