Patents by Inventor Mari Shimizu

Mari Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200197446
    Abstract: The purpose of the present invention is to provide a novel medical application of pluripotent stem cells (muse cells) in regeneration medicine. The present invention provides a cell preparation and a pharmaceutical composition which are for amelioration and treatment of brain disorders resulting from fetal growth retardation, such as abnormal motor quality or abnormal neurological development, and which contain SSEA-3 positive pluripotent stem cells isolated from a mesenchymal tissue from a live body or cultured mesenchymal cells. It is assumed that this cell preparation is based on a mechanism where muse cells that are administered to objects having the disorders are engrafted on an impaired brain tissue, thereby ameliorating or treating the disorders.
    Type: Application
    Filed: June 20, 2018
    Publication date: June 25, 2020
    Applicants: National University Corporation Nagoya University, TOHOKU UNIVERSITY, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, Life Science Institute, Inc.
    Inventors: Yoshiaki SATO, Yuma KITASE, Shinobu SHIMIZU, Masaaki MIZUNO, Masahiro HAYAKAWA, Mari DEZAWA, Masahiro TSUJI
  • Publication number: 20200118733
    Abstract: A coil component includes a body and a coil conductor embedded in the body. The body includes a magnetic layer and a non-magnetic layer. The magnetic layer is formed of a composite material including a metal particle and a resin material, and the non-magnetic layer is arranged to block between at least one of top and bottom surfaces of the body and the coil conductor.
    Type: Application
    Filed: December 16, 2019
    Publication date: April 16, 2020
    Applicant: Murata Manufacturing Co., Ltd.
    Inventors: Noriko SHIMIZU, Gota SHINOHARA, Mikito SUGIYAMA, Mari YONEMURA
  • Publication number: 20200118734
    Abstract: A coil component includes a body and a coil conductor embedded in the body. The body includes a magnetic layer and a non-magnetic layer. The magnetic layer is formed of a composite material including a metal particle and a resin material, and the non-magnetic layer is arranged not to extend through a winding portion of the coil conductor or not to entirely extend through the body.
    Type: Application
    Filed: December 16, 2019
    Publication date: April 16, 2020
    Applicant: Murata Manufacturing Co., Ltd.
    Inventors: Noriko SHIMIZU, Gota SHINOHARA, Mikito SUGIYAMA, Mari YONEMURA
  • Publication number: 20200017558
    Abstract: An object of this invention is to provide a streptavidin mutant reduced in affinity to the naturally-occurring biotin, and to provide a modified biotin which shows a high affinity to such streptavidin mutant reduced in affinity to the naturally-occurring biotin. This invention can provide a compound composed of a dimer of modified biotin, a streptavidin mutant, angsd usage of them.
    Type: Application
    Filed: July 16, 2019
    Publication date: January 16, 2020
    Applicant: SAVID THERAPEUTICS INC.
    Inventors: Akira SUGIYAMA, Hirofumi DOI, Tatsuhiko KODAMA, Tsuyoshi INOUE, Eiichi MIZOHATA, Tatsuya KAWATO, Tomohiro MESHIZUKA, Motomu KANAI, Yohei SHIMIZU, Noriaki TAKASU, Mari TAKATSU
  • Publication number: 20190290702
    Abstract: The present invention addresses the problem of providing a novel use of pluripotent stem cells (Muse cells) for medical purposes in regenerative medicine. The present invention provides a cell preparation and a pharmaceutical composition both for ameliorating and treating perinatal brain damage including learning disability and motor disability, each of the cell preparation and the pharmaceutical composition containing SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue collected from a living body or cultured mesenchymal cells. The cell preparation according to the present invention relies on a mechanism that Muse cells are administered to a subject having the above-mentioned damage to cause the engraftment of the Muse cells in a damaged brain tissue, thereby ameliorating and treating the damage.
    Type: Application
    Filed: May 16, 2017
    Publication date: September 26, 2019
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, LIFE SCIENCE INSTITUTE, INC.
    Inventors: Yoshiaki Sato, Toshihiko Suzuki, Shinobu Shimizu, Masaaki Mizuno, Masahiro Hayakawa, Mari Dezawa
  • Publication number: 20190240262
    Abstract: The purpose of the present invention is to provide a novel medical use of pluripotent stem cells (Muse cells) in the regenerative medicine area. Provided are a cell preparation and a medicinal composition for ameliorating and treating chronic lung disease in newborns, said cell preparation and medicinal composition comprising SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue in a living body or cultured mesenchymal cells. The cell preparation according to the present invention is based on a mechanism whereby the aforesaid disease is ameliorated and treated by administering Muse cells to a subject suffering from the disease and engrafting the cells in lung tissues.
    Type: Application
    Filed: August 3, 2017
    Publication date: August 8, 2019
    Applicants: National University Corporation Nagoya University, Life Science Institute, Inc., TOHOKU UNIVERSITY
    Inventors: Yoshiaki SATO, Toshihiko SUZUKI, Shinobu SHIMIZU, Masaaki MIZUNO, Masahiro HAYAKAWA, Mari DEZAWA
  • Publication number: 20190224945
    Abstract: There is provided a release film comprising a substrate film and a resin layer provided on at least one surface of a substrate film, wherein the resin layer comprises 100 parts by mass of an acid-modified polyolefin resin, 1 to 20 parts by mass of a crosslinking agent and 10 to 1,000 parts by mass of a polyvinyl alcohol having a saponification rate of 99% or lower.
    Type: Application
    Filed: September 20, 2017
    Publication date: July 25, 2019
    Applicant: UNITIKA LTD.
    Inventors: Mari Shimizu, Kouhei Tanaka, Nobuyasu Okumura
  • Publication number: 20190180909
    Abstract: A coil component including an element assembly and a coil conductor embedded in the element assembly. The element assembly includes a first magnetic layer and a second magnetic layer that constitute a first principal surface and a second principal surface, respectively, where the first principal surface and the second principal surface are opposite to each other in the element assembly. The first magnetic layer has a higher relative magnetic permeability than the second magnetic layer. At least part of a winding portion of the coil conductor is located in the first magnetic layer. The first magnetic layer contains metal magnetic particles and a resin, and the second magnetic layer contains metal magnetic particles, a resin, and zinc oxide particles. The metal magnetic particles and the zinc oxide particles are dispersed in the resin.
    Type: Application
    Filed: November 5, 2018
    Publication date: June 13, 2019
    Applicant: Murata Manufacturing Co., Ltd.
    Inventors: Gota SHINOHARA, Noriko SHIMIZU, Keiichi ISHIDA, Hironobu KUBOTA, Mari YONEMURA, Takao KAWACHI
  • Publication number: 20190002281
    Abstract: An aluminum nitride film includes a polycrystalline aluminum nitride. A withstand voltage of the aluminum nitride film is 100 kV/mm or more.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Applicants: SHIBAURA INSTITUTE OF TECHNOLOGY, TOSHIBA MATERIALS CO., LTD.
    Inventors: Atsushi YUMOTO, Mari SHIMIZU, Tetsuo INOUE, Takashi HINO, Shuichi SAITO
  • Publication number: 20160359078
    Abstract: A composition for forming an n-type diffusion layer, comprising glass particles that comprise a donor element, a dispersing medium, and an organometallic compound; a method of forming an n-type diffusion layer; a method of producing a semiconductor substrate with n-type diffusion layer; and a method of producing a photovoltaic cell element.
    Type: Application
    Filed: August 20, 2014
    Publication date: December 8, 2016
    Applicant: HITACHI CHEMICAL COMPANY, LTD.
    Inventors: Tetsuya SATO, Masato YOSHIDA, Takeshi NOJIRI, Yasushi KURATA, Toranosuke ASHIZAWA, Yoichi MACHII, Mitsunori IWAMURO, Akihiro ORITA, Mari SHIMIZU, Elichi SATOU
  • Patent number: 9410245
    Abstract: A gas barrier plastic molded product having high gas barrier properties is provided. The gas barrier plastic molded product is a gas barrier plastic molded product comprising a plastic molded product and a gas barrier thin film provided on the surface of the plastic molded product, in which the gas barrier thin film contains silicon (Si), carbon (C), oxygen (O) and hydrogen (H) as constituent elements, and comprises a Si-containing layer having a Si content percentage represented by (Mathematical Formula 1) of 40.1% or more: Si content percentage [%]={(Si content [atomic %])/ (total content of Si, O and C [atomic %])}×100??(Mathematical Formula 1) wherein in Mathematical Formula 1, the content of Si, O or C is a content thereof in the items of the three elements of Si, O and C.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: August 9, 2016
    Assignee: KIRIN BEER KABUSHIKI KAISHA
    Inventors: Mari Shimizu, Eitaro Matsui, Aiko Sato, Masaki Nakaya, Hiroyasu Tabuchi
  • Publication number: 20150017754
    Abstract: The invention provides composition for forming an n-type diffusion layer, the composition comprising a compound containing a donor element, a dispersing medium, and an organic filler; a method for producing a semiconductor substrate having an n-type diffusion layer; and a method for producing a photovoltaic cell element.
    Type: Application
    Filed: January 10, 2013
    Publication date: January 15, 2015
    Inventors: Tetsuya Sato, Masato Yoshida, Takeshi Nojiri, Toranosuke Ashizawa, Yasushi Kurata, Yoichi Machii, Mitsunori Iwamuro, Akihiro Orita, Mari Shimizu
  • Patent number: 8932676
    Abstract: Provided is a method for producing a gas barrier plastic molded body by forming a gas barrier thin film which is substantially colorless and has gas barrier properties, on the surface of a plastic molded body by a heating element CVD method using only raw material gases that are highly safe.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: January 13, 2015
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Masaki Nakaya, Midori Takiguchi, Mari Shimizu, Aiko Sato, Hiroyasu Tabuchi, Eitaro Matsui
  • Patent number: 8883257
    Abstract: Disclosed herein is a method for producing a plastic container coated with a thin film that is excellent in gas barrier properties, film coloration and film adhesiveness without using an external electrode having a special shape while suppressing deposition of foreign matters such as carbon powders.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: November 11, 2014
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Masaki Nakaya, Mari Shimizu
  • Publication number: 20130323423
    Abstract: Provided is a method for producing a gas barrier plastic molded body by forming a gas barrier thin film which is substantially colorless and has gas barrier properties, on the surface of a plastic molded body by a heating element CVD method using only raw material gases that are highly safe.
    Type: Application
    Filed: December 28, 2011
    Publication date: December 5, 2013
    Applicant: KIRIN BEER KABUSHIKI KAISHA
    Inventors: Masaki Nakaya, Midori Takiguchi, Mari Shimizu, Aiko Sato, Hiroyasu Tabuchi, Eitaro Matsui
  • Publication number: 20130316108
    Abstract: A gas barrier plastic molded product having high gas barrier properties is provided. The gas barrier plastic molded product is a gas barrier plastic molded product comprising a plastic molded product and a gas barrier thin film provided on the surface of the plastic molded product, in which the gas barrier thin film contains silicon (Si), carbon (C), oxygen (O) and hydrogen (H) as constituent elements, and comprises a Si-containing layer having a Si content percentage represented by (Mathematical Formula 1) of 40.1% or more: Si content percentage[%]={(Si content[atomic %])/(total content of Si, O and C [atomic %])}×100??(Mathematical Formula 1) wherein in Mathematical Formula 1, the content of Si, O or C is a content thereof in the items of the three elements of Si, O and C.
    Type: Application
    Filed: December 28, 2011
    Publication date: November 28, 2013
    Applicant: KIRIN BEER KABUSHIKI KAISHA
    Inventors: Mari Shimizu, Eitaro Matsui, Aiko Sato, Masaki Nakaya, Hiroyasu Tabuchi
  • Publication number: 20120052215
    Abstract: Disclosed herein is a method for producing a plastic container coated with a thin film that is excellent in gas barrier properties, film coloration and film adhesiveness without using an external electrode having a special shape while suppressing deposition of foreign matters such as carbon powders.
    Type: Application
    Filed: June 25, 2009
    Publication date: March 1, 2012
    Applicant: KIRIN BEER KABUSHIKI KAISHA
    Inventors: Masaki Nakaya, Mari Shimizu