Patents by Inventor Mari Tabuchi

Mari Tabuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9266106
    Abstract: A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: February 23, 2016
    Assignee: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Yasuhisa Fujita, Haruo Takeshita, Junko Fujihara, Yutaka Fukui, Mari Tabuchi
  • Publication number: 20150027893
    Abstract: A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).
    Type: Application
    Filed: February 25, 2013
    Publication date: January 29, 2015
    Inventors: Yasuhisa Fujita, Haruo Takeshita, Junko Fujihara, Yutaka Fukui, Mari Tabuchi
  • Patent number: 7708870
    Abstract: To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteosome analysis and medical diagnosis.
    Type: Grant
    Filed: December 25, 2002
    Date of Patent: May 4, 2010
    Assignee: Japan Science and Tecnology Agency
    Inventors: Mari Tabuchi, Yoshinobu Baba
  • Patent number: 7517441
    Abstract: By using an electrophoretic buffer comprising a polymerized polymer micelle formed by the steps comprising dispersing into an aqueous medium a block copolymer represented by HPLS-HPBS-PLZA, wherein HPLS is a hydrophilic polymer segment, HPBS is a hydrophobic polymer segment, and PLZA is a polymerizable group having an ethylenically unsaturated double bond, and polymerizing the block copolymer as a buffer for a capillary electrophoresis or a microchip electrophoresis, pressurizing the sample after introduction at a given pressure for a given time period, and electrophoresing in an electrophoretic electric field, a polymer compound such as DNA can be separated rapidly and in high separation ability.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: April 14, 2009
    Assignee: Japan Science and Technology Agency
    Inventors: Yoshinobu Baba, Kazunori Kataoka, Mari Tabuchi, Yukio Nagasaki, Yasuko Tanaka, Chie Kuwahara
  • Patent number: 7410559
    Abstract: A separation carrier comprising ?-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis, wherein a sample comprising macromolecular compounds is run in the presence of the running buffer; a method of capillary electrophoresis or microchip electrophoresis, comprising the step of injecting the sample by an electrical injection or application of pressure; and a method for analyzing macromolecular compounds by the method of capillary electrophoresis or microchip electrophoresis. According to the present invention, it is possible to achieve high resolution quickly. Therefore, the methods are useful in the High Through-put screening analysis of proteins or sugar chains in gene analysis, proteome analysis or glycome analysis, and applicable in medical diagnostic apparatuses and the elucidation of biological functions, mechanisms of onset of diseases, etc.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: August 12, 2008
    Assignee: Japan Science and Technology Agency
    Inventors: Mari Tabuchi, Yoshinobu Baba
  • Publication number: 20060040396
    Abstract: By using an electrophoretic buffer comprising a polymerized polymer micelle formed by the steps comprising dispersing into an aqueous medium a block copolymer represented by HPLS-HPBS-PLZA, wherein HPLS is a hydrophilic polymer segment, HPBS is a hydrophobic polymer segment, and PLZA is a polymerizable group having an ethylenically unsaturated double bond, and polymerizing the block copolymer as a buffer for a capillary electrophoresis or a microchip electrophoresis, pressurizing the sample after introduction at a given pressure for a given time period, and electrophoresing in an electrophoretic electric field, a polymer compound such as DNA can be separated rapidly and in high separation ability.
    Type: Application
    Filed: March 13, 2003
    Publication date: February 23, 2006
    Applicant: Japan Science and Technology Agency
    Inventors: Yoshinobu Baba, Kazumori Kataoka, Mari Tabuchi, Yukio Nagasaki, Yasuko Tanaka, Chie Kuwahara
  • Publication number: 20050016850
    Abstract: To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteosome analysis and medical diagnosis.
    Type: Application
    Filed: December 25, 2002
    Publication date: January 27, 2005
    Inventors: Mari Tabuchi, Yoshinobu Baba
  • Patent number: 6818434
    Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: November 16, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
  • Publication number: 20040168917
    Abstract: A separation carrier comprising &bgr;-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis, wherein a sample comprising macromolecular compounds is run in the presence of the running buffer; a method of capillary electrophoresis or microchip electrophoresis, comprising the step of injecting the sample by an electrical injection or application of pressure; and a method for analyzing macromolecular compounds by the method of capillary electrophoresis or microchip electrophoresis. According to the present invention, it is possible to achieve high resolution quickly. Therefore, the methods are useful in the High Through-put screening analysis of proteins or sugar chains in gene analysis, proteome analysis or glycome analysis, and applicable in medical diagnostic apparatuses and the elucidation of biological functions, mechanisms of onset of diseases, etc.
    Type: Application
    Filed: December 1, 2003
    Publication date: September 2, 2004
    Inventors: Mari Tabuchi, Yoshinobu Baba
  • Publication number: 20030032148
    Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
    Type: Application
    Filed: June 5, 2002
    Publication date: February 13, 2003
    Applicant: Bio-Polymer Research Co., Ltd.
    Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
  • Publication number: 20010044138
    Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
    Type: Application
    Filed: May 1, 2001
    Publication date: November 22, 2001
    Applicant: Bio-Polymer Research Co., Ltd.
    Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
  • Patent number: 6140105
    Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: October 31, 2000
    Assignee: Bio-Polymer Research Co., Ltd.
    Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
  • Patent number: 5962277
    Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: October 5, 1999
    Assignee: Bio-Polymer Research Co., Ltd.
    Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga