Patents by Inventor Mari Tabuchi
Mari Tabuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9266106Abstract: A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).Type: GrantFiled: February 25, 2013Date of Patent: February 23, 2016Assignee: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Yasuhisa Fujita, Haruo Takeshita, Junko Fujihara, Yutaka Fukui, Mari Tabuchi
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Publication number: 20150027893Abstract: A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).Type: ApplicationFiled: February 25, 2013Publication date: January 29, 2015Inventors: Yasuhisa Fujita, Haruo Takeshita, Junko Fujihara, Yutaka Fukui, Mari Tabuchi
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Patent number: 7708870Abstract: To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteosome analysis and medical diagnosis.Type: GrantFiled: December 25, 2002Date of Patent: May 4, 2010Assignee: Japan Science and Tecnology AgencyInventors: Mari Tabuchi, Yoshinobu Baba
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Patent number: 7517441Abstract: By using an electrophoretic buffer comprising a polymerized polymer micelle formed by the steps comprising dispersing into an aqueous medium a block copolymer represented by HPLS-HPBS-PLZA, wherein HPLS is a hydrophilic polymer segment, HPBS is a hydrophobic polymer segment, and PLZA is a polymerizable group having an ethylenically unsaturated double bond, and polymerizing the block copolymer as a buffer for a capillary electrophoresis or a microchip electrophoresis, pressurizing the sample after introduction at a given pressure for a given time period, and electrophoresing in an electrophoretic electric field, a polymer compound such as DNA can be separated rapidly and in high separation ability.Type: GrantFiled: March 13, 2003Date of Patent: April 14, 2009Assignee: Japan Science and Technology AgencyInventors: Yoshinobu Baba, Kazunori Kataoka, Mari Tabuchi, Yukio Nagasaki, Yasuko Tanaka, Chie Kuwahara
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Patent number: 7410559Abstract: A separation carrier comprising ?-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis, wherein a sample comprising macromolecular compounds is run in the presence of the running buffer; a method of capillary electrophoresis or microchip electrophoresis, comprising the step of injecting the sample by an electrical injection or application of pressure; and a method for analyzing macromolecular compounds by the method of capillary electrophoresis or microchip electrophoresis. According to the present invention, it is possible to achieve high resolution quickly. Therefore, the methods are useful in the High Through-put screening analysis of proteins or sugar chains in gene analysis, proteome analysis or glycome analysis, and applicable in medical diagnostic apparatuses and the elucidation of biological functions, mechanisms of onset of diseases, etc.Type: GrantFiled: May 29, 2001Date of Patent: August 12, 2008Assignee: Japan Science and Technology AgencyInventors: Mari Tabuchi, Yoshinobu Baba
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Publication number: 20060040396Abstract: By using an electrophoretic buffer comprising a polymerized polymer micelle formed by the steps comprising dispersing into an aqueous medium a block copolymer represented by HPLS-HPBS-PLZA, wherein HPLS is a hydrophilic polymer segment, HPBS is a hydrophobic polymer segment, and PLZA is a polymerizable group having an ethylenically unsaturated double bond, and polymerizing the block copolymer as a buffer for a capillary electrophoresis or a microchip electrophoresis, pressurizing the sample after introduction at a given pressure for a given time period, and electrophoresing in an electrophoretic electric field, a polymer compound such as DNA can be separated rapidly and in high separation ability.Type: ApplicationFiled: March 13, 2003Publication date: February 23, 2006Applicant: Japan Science and Technology AgencyInventors: Yoshinobu Baba, Kazumori Kataoka, Mari Tabuchi, Yukio Nagasaki, Yasuko Tanaka, Chie Kuwahara
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Publication number: 20050016850Abstract: To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteosome analysis and medical diagnosis.Type: ApplicationFiled: December 25, 2002Publication date: January 27, 2005Inventors: Mari Tabuchi, Yoshinobu Baba
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Patent number: 6818434Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.Type: GrantFiled: June 5, 2002Date of Patent: November 16, 2004Assignee: Ajinomoto Co., Inc.Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
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Publication number: 20040168917Abstract: A separation carrier comprising &bgr;-1,3-glucan and/or methyl cellulose; a running buffer comprising the separation carrier; a method of capillary electrophoresis or microchip electrophoresis, wherein a sample comprising macromolecular compounds is run in the presence of the running buffer; a method of capillary electrophoresis or microchip electrophoresis, comprising the step of injecting the sample by an electrical injection or application of pressure; and a method for analyzing macromolecular compounds by the method of capillary electrophoresis or microchip electrophoresis. According to the present invention, it is possible to achieve high resolution quickly. Therefore, the methods are useful in the High Through-put screening analysis of proteins or sugar chains in gene analysis, proteome analysis or glycome analysis, and applicable in medical diagnostic apparatuses and the elucidation of biological functions, mechanisms of onset of diseases, etc.Type: ApplicationFiled: December 1, 2003Publication date: September 2, 2004Inventors: Mari Tabuchi, Yoshinobu Baba
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Publication number: 20030032148Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.Type: ApplicationFiled: June 5, 2002Publication date: February 13, 2003Applicant: Bio-Polymer Research Co., Ltd.Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
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Publication number: 20010044138Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.Type: ApplicationFiled: May 1, 2001Publication date: November 22, 2001Applicant: Bio-Polymer Research Co., Ltd.Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
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Patent number: 6140105Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.Type: GrantFiled: July 23, 1999Date of Patent: October 31, 2000Assignee: Bio-Polymer Research Co., Ltd.Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga
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Patent number: 5962277Abstract: Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.Type: GrantFiled: January 9, 1998Date of Patent: October 5, 1999Assignee: Bio-Polymer Research Co., Ltd.Inventors: Kunihiko Watanabe, Hiroshi Takemura, Mari Tabuchi, Naoki Tahara, Hiroshi Toyosaki, Yasushi Morinaga, Takayasu Tsuchida, Hisato Yano, Fumihiro Yoshinaga