Patents by Inventor Maria Acs

Maria Acs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diastereomer salts of phenylalanine and N-acyl derivatives thereof and process for the separation of optically active phenylalanine and N-acyl derivatives thereof
    Patent number: 4642205
    Abstract: The present invention relates to the separation of optically active phenylalanine and N-acyl derivatives thereof and novel diastereomer salts of the said compounds.According to the invention a racemic compound of the formula ##STR1## is reacted with an optically active resolving agent of the formula ##STR2## in a polar solvent and/or a mixture of solvents comprising at least one apolar solvent and optionally an achiral acid or base, thereafter(a) when using the D-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the L-isomer of the compound of the formula I is separated, or(b) when using the L-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the D-isomer of the compound of the formula I is separated, andthe enantiomers of the compound of the formula I from the diastereomer salt or the mother liquor are liberated by the aid of an achiral acid or base and the optically active product is separated in crystalline form.
    Type: Grant
    Filed: November 18, 1985
    Date of Patent: February 10, 1987
    Assignee: Alkaloida Vegyeszeti Gyar
    Inventors: Maria Acs, Ferenc Faigl, Elemer Fogassy