Patents by Inventor Maria Allhorn

Maria Allhorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment for IgE-mediated disease
    Patent number: 9707279
    Abstract: The invention provides an EndoS polypeptide, or a polynucleotide encoding an EndoS polypeptide, for use in a method for treating or preventing a disease or condition mediated by IgE antibodies.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: July 18, 2017
    Assignee: Hansa Medical AB
    Inventors: Mattias Collin, Rolf Lood, Karl Carlstrom, Maria Allhorn, Jonathan Sjogren, Falk Nimmerjahn
  • Endoglycosidase from and methods using it
    Patent number: 9493752
    Abstract: The invention provides an endoglycosidase, referred to as EndoS49 and having the amino acid sequence of SEQ ID NO: 1. EndoS49 was isolated from Streptococcus pyogenes strain NZ131 and is a homolog of EndoS. EndoS49 has specific endoglycosidase activity on native IgG and cleaves a larger variety of Fc glycans than EndoS. A mutant thereof where the glutamic acid at position 186 of SEQ ID NO: 1 was substituted was produced: said mutant lacks endoglycosidase activity but is capable of binding to IgG. Methods using EndoS49, deletions thereof and said mutant, especially for assessing glycosylation of IgG or for isolating IgG are disclosed.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: November 15, 2016
    Assignee: Genovis AB
    Inventors: Mattias Collin, Maria Allhorn, Jonathan Sjögren
  • ENDOGLYCOSIDASE FROM STREPTOCOCCUS PYOGENES AND METHODS USING IT
    Publication number: 20140302519
    Abstract: The invention provides an endoglycosidase, referred to as EndoS49 and having the amino acid sequence of SEQ ID NO: 1. EndoS49 was isolated from Streptococcus pyogenes strain NZ131 and is a homolog of EndoS. EndoS49 has specific endoglycosidase activity on native IgG and cleaves a larger variety of Fc glycans than EndoS. A mutant thereof where the glutamic acid at position 186 of SEQ ID NO: 1 was substituted was produced: said mutant lacks endoalvcosidase activity but is capable of binding to IgG. Methods using EndoS49, deletions thereof and said mutant, especially for assessing glycosylation of IgG or for isolating IgG are disclosed.
    Type: Application
    Filed: September 12, 2012
    Publication date: October 9, 2014
    Applicant: Genovis AB
    Inventors: Mattias Collin, Maria Allhorn, Jonathan Sjögren
  • TREATMENT FOR IgE-MEDIATED DISEASE
    Publication number: 20140065128
    Abstract: The invention provides an EndoS polypeptide, or a polynucleotide encoding an EndoS polypeptide, for use in a method for treating or preventing a disease or condition mediated by IgE antibodies.
    Type: Application
    Filed: March 5, 2012
    Publication date: March 6, 2014
    Applicant: HANSA MEDICAL AB
    Inventors: Mattias Collin, Rolf Lood, Karl Carlstrom, Maria Allhorn, Jonathan Sjogren, Falk Nimmerjahn
  • Method of assessing glycosylation state or functional quality of an IgG containing sample
    Patent number: 8323908
    Abstract: The inventions provides methods and kits for the dissociation of Fc?-receptor-IgG complexes, and methods and kits for the isolation of IgG and Fc and Fab fragments of IgG.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: December 4, 2012
    Assignee: Genovis AB
    Inventors: Maria Allhorn, Anders Olin, Falk Nimmerjahn, Mattias Collin
  • DEGLYCOSYLATED ANTIBODIES
    Publication number: 20110318340
    Abstract: The present invention provides an antibody, or antibody fragment, with modified glycosylation for use in treating or preventing a disease or condition, where the antibody or fragment: (a) suppresses an inflammatory condition forming part of the disease or condition to be treated or prevented; and/or (b) displays increased efficacy and/or decreased side effects in comparision to treatment or prevention with the corresponding antibody with unmodified glycosylation.
    Type: Application
    Filed: November 18, 2009
    Publication date: December 29, 2011
    Applicant: Hansa Medical AB
    Inventors: Mattias Collin, Maria Allhorn, Rikard Holmdahl, Kutty Selva Nandakumar
  • METHODS AND KITS FOR DISSOCIATING FCGAMMA-RECEPTOR-IGG COMPLEXES AND FOR IGG PURIFICATION AND DETECTION
    Publication number: 20100317083
    Abstract: The inventions provides methods and kits for the dissociation of Fc?-receptor-IgG complexes, and methods and kits for the isolation of IgG and Fc and Fab fragments of IgG.
    Type: Application
    Filed: September 11, 2008
    Publication date: December 16, 2010
    Inventors: Maria Allhorn, Anders Olin, Falk Nimmerjahn, Mattias Collin