Patents by Inventor Maria Amparo Lago

Maria Amparo Lago has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CALCILYTIC COMPOUNDS
    Publication number: 20070249702
    Abstract: The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Application
    Filed: January 30, 2007
    Publication date: October 25, 2007
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Calcilytic compounds
    Patent number: 7202261
    Abstract: The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: April 10, 2007
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Calcilytic compounds
    Patent number: 7109238
    Abstract: Novel calcilytic compounds and methods of using them are provided.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: September 19, 2006
    Assignees: Smith Kline Beecham Corporation, NPS Pharmaceuticals, Inc.
    Inventors: Maria Amparo Lago, James Francis Callahan, Pradip Kumar Bhatnagar, Eric G. Del Mar, William M. Bryan, Joelle L. Burgess
  • Calcilytic compounds
    Patent number: 6818660
    Abstract: The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: November 16, 2004
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Calcilytic compounds
    Publication number: 20040192741
    Abstract: Novel calcilytic compounds and methods of using them are provided.
    Type: Application
    Filed: January 21, 2004
    Publication date: September 30, 2004
    Applicant: SmithKline Beecham Corporation & NPS Pharmaceuticals
    Inventors: Maria Amparo Lago, James Francis Callahan, Pradip Kumar Bhatnagar, Eric G. Del Mar, William M. Bryan, Joelle L. Burgess
  • Calcilytic compounds
    Patent number: 6521667
    Abstract: The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: February 18, 2003
    Assignees: NPS Pharmaceuticals, Inc., SmithKline Beecham, PLC, SmithKline Beecham, Corp.
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Endothelin receptor antagonists
    Patent number: 6448260
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: September 10, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
  • Calcilytic compounds
    Patent number: 6432656
    Abstract: The present invention features calcilytic compounds. “calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: August 13, 2002
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Calcilytic compounds
    Publication number: 20020099220
    Abstract: The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Application
    Filed: October 19, 2001
    Publication date: July 25, 2002
    Applicant: NPS Pharmaceuticals, Inc.
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Calcilytic compounds
    Patent number: 6395919
    Abstract: Novel calcilytic compounds, pharmaceuticals compositions cotaining said compounds and their use as calcium receptor antagonists.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: May 28, 2002
    Assignees: SmithKline Beecham Corporation, NPS Pharmaceuticals
    Inventors: Pradip Kumar Bhatnagar, Joelle Lorraine Burgess, James Francis Callahan, Raul Rolando Calvo, Eric G. Del Mar, Maria Amparo Lago, Thomas The Nguyen
  • Calcilytic compounds and method of use
    Publication number: 20020052509
    Abstract: Calcilytic compounds and compositions and their use in treating abnormal bone or mineral homeostasis.
    Type: Application
    Filed: December 4, 2001
    Publication date: May 2, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Pradip Kumar Bhatnagar, James Francis Callahan, Eric G. Del Mar, Maria Amparo Lago
  • Endothelin receptor antagonists
    Publication number: 20020002177
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Application
    Filed: July 10, 2001
    Publication date: January 3, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
  • Calcilytic compounds
    Patent number: 6335338
    Abstract: Novel calcilytic compounds are provided.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: January 1, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Pradip Bhatnagar, Maria Amparo Lago
  • Calcilytic compounds
    Patent number: 6294531
    Abstract: Novel arylalkylamino compounds exhibiting calcilytic properties are provided.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: September 25, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert M. Barmore, Pradip Kumar Bhatnagar, William M. Bryan, Joelle Lorraine Burgess, James Francis Callahan, Raul Rolando Calvo, Eric G. Del Mar, Maria Amparo Lago, Thomas The Nguyen, Derek Sheehan, Robert Lawrence Smith, Linda Sue Southall, Bradford C. Van Wagenen
  • Calcilytic compounds
    Patent number: 6291459
    Abstract: A compound selected from Formula (I) hereinbelow: or a pharmaceutically acceptable salt thereof, wherein m is an integer from 0 to 2; n is an integer from 1 to 3; X is selected from the group consisting of CN, NO2, Cl, F, and H; Y is selected from the group consisting of Cl, F, Br, I and H; and Q and Z are, independently, selected from the group consisting of H, R1, SO2R1′, R1C(O)OR1″, SO2NR1′R1″, C(O)NR1′R1″, NR1′SO2R″1, wherein R1, R1′ and R1″ are independently selected from the group consisting of hydrogen, C1-4 alkyl, C3-6 cycloalkyl, C2-5 alkenyl, C2-5 alkynyl, heterocycloalkyl, aryl and aryl C1-4 alkyl; or R1′ and R1″ together form a 3 to 7 membered optionally substituted heterocyclic ring; wherein any substituents are selected from the group consisting of CN, aryl, CO2R, CO2NHR, OH, OR, NH2, halo, CF3, OCF3 and NO2; wherein R represents H, C1-4 alkyl, and C3-6 cycloalkyl; and A is phenyl or naphthyl, unsubstit
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: September 18, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Pradip Bhatnagar, Maria Amparo Lago
  • Endothelin receptor antagonists
    Patent number: 6274737
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: August 14, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
  • Endothelin receptor antagonists
    Patent number: 6271399
    Abstract: Indane and indene compounds are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 7, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
  • Endothelin receptor antagonists
    Patent number: 6087389
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: July 11, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
  • Method of using calcilytic compounds
    Patent number: 6022894
    Abstract: The present invention features calcilytic compounds. "Calcilytic compounds" refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial effect in a patient; and techniques which can be used to obtain additional calcilytic compounds.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: February 8, 2000
    Assignees: NPS Pharmaceuticals, Inc., SmithKline Beecham, Corp., SmithKline Beecham, PLC
    Inventors: Eric G. Del Mar, Robert M. Barmore, Derek Sheehan, Bradford C. Van Wagenen, James F. Callahan, Richard M. Keenan, Nikesh R. Kotecha, Maria Amparo Lago, Linda Sue Southall, Mervyn Thompson
  • Endothelin receptor antagonists
    Patent number: 5817693
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: October 6, 1998
    Inventors: Russell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff