Patents by Inventor Maria B. Grant

Maria B. Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCING VESSEL LESION HOMING AND REPAIR POTENTIAL OF STEM CELLS
    Publication number: 20140356332
    Abstract: Disclosed herein are methods of enhancing repair of vascular lesions involving the administration of cells in which TGF-? expression and/or activity has been transiently blocked. Other methods involve the administration of a TGF-? blocking agent to a subject who has a vascular lesion or is at risk of developing a vascular lesion. Alternatively, a TGF-? blocking agent and treated cells are co-administered to a subject in need thereof.
    Type: Application
    Filed: May 7, 2014
    Publication date: December 4, 2014
    Inventors: Stephen H. Bartelmez, Maria B. Grant
  • Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation
    Patent number: 7754692
    Abstract: The subject invention provides dipeptides useful in preventing pathological proliferation of blood vessels. The dipeptides of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: July 13, 2010
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Josef Neu, Maria B. Grant
  • Materials and Methods for Treatment of Pathological Ocular Vascular Proliferation
    Publication number: 20090192226
    Abstract: The subject invention provides for the administration of docosahexaenoic acid in preventing pathological proliferation of blood vessels. The compositions of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.
    Type: Application
    Filed: December 17, 2008
    Publication date: July 30, 2009
    Inventors: Josef Neu, Maria B. Grant, Joshua Anthony, Kristin Morris, Eduard Poels, Deborah Schade, Hugh Tucker
  • Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation
    Patent number: 7148199
    Abstract: The subject invention provides dipeptides useful in preventing pathological proliferation of blood vessels. The dipeptides of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 12, 2006
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Josef Neu, Maria B. Grant
  • Method for identifying and using A2B adenosine receptor antagonists to mediate mammalian cell proliferation
    Patent number: 6894021
    Abstract: This invention concerns methods for identifying A2B adenosine receptor agonists and antagonists as well as methods for using A2B adenosine receptor antagonists to treat cell proliferation orders mediated by the A2B adenosine receptor.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: May 17, 2005
    Assignees: CV Therapeutics, Inc., University of Florida Research Foundation
    Inventors: Luiz Belardinelli, Maria B. Grant
  • Localization of A2B AdoR on human normal and diseased tissue: the use of anti-A2B antibody to diagnose and treat human tumors
    Publication number: 20030035802
    Abstract: The invention provides methods of detection, prevention, amelioration, and treatment for angiogenesis, including angiogenesis associated with colon cancer and glioma. The methods comprise the use of an anti-A2B antibody.
    Type: Application
    Filed: August 9, 2002
    Publication date: February 20, 2003
    Inventors: Dewan Zeng, Luiz Belardinelli, Maria B. Grant
  • Method for identifying and using A2B adenosine receptor antagonists to mediate mammalian cell proliferation
    Publication number: 20020002142
    Abstract: This invention concerns methods for identifying A2B adenosine receptor agonists and antagonists as well as methods for using A2B. adenosine receptor antagonists to treat cell proliferation orders mediated by the A2B adenosine receptor.
    Type: Application
    Filed: February 16, 2001
    Publication date: January 3, 2002
    Inventors: Luiz Belardinelli, Maria B. Grant