Patents by Inventor Maria B. Lopez

Maria B. Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing antifungal fermentation products and compositions thereof
    Patent number: 5196327
    Abstract: A mixture of derivatives of 2-amino-3,4,5,14-tetrahydroxy-6-eicosenoic acid has been isolated from a culture medium after cultivation of microorganisms belonging to the genus Aspergillus. The compounds are useful as antifungal agents.
    Type: Grant
    Filed: May 8, 1991
    Date of Patent: March 23, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Maria B. Lopez, Richard L. Monaghan
  • Antifungal agent
    Patent number: 5164375
    Abstract: A phospholipid having the formula ##STR1## is described. The compound has antifungal properties.
    Type: Grant
    Filed: September 27, 1991
    Date of Patent: November 17, 1992
    Assignee: Merck & Company, Inc.
    Inventors: Frank VanMiddlesworth, Kenneth E. Wilson, Otto D. Hensens, Deborah Zink, Maria B. Lopez
  • Antifungal fermentation products and compositions thereof
    Patent number: 5019593
    Abstract: A mixture of derivatives of 2-amino-3,4,5,14-tetrahydroxy-6-eicosenoic acid has been isolated from a culture medium after cultivation of microorganisms belonging to the genus Aspergillus. The compounds are useful as antifungal agents.
    Type: Grant
    Filed: July 29, 1987
    Date of Patent: May 28, 1991
    Assignee: Merck & Co., Inc.
    Inventors: George M. Garrity, Maria B. Lopez, Otto D. Hensens, Richard L. Monaghan, Deborah L. Zink
  • Hypocholesteremic fermentation products and process of preparation
    Patent number: 4420491
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
    Type: Grant
    Filed: May 28, 1981
    Date of Patent: December 13, 1983
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Henry Joshua, Maria B. Lopez
  • Hypocholesteremic fermentation products and products of preparation
    Patent number: 4294846
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: October 13, 1981
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Henry Joshua, Maria B. Lopez