Patents by Inventor Maria Carmen Arilla Rodriguez

Maria Carmen Arilla Rodriguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYPOALLERGENIC HYBRID PROTEINS OF MAJOR GROUP 1 AND 2 MITE ALLERGENS FOR USE IN THE TREATMENT OF ALLERGIES
    Publication number: 20150152148
    Abstract: The present invention refers to recombinant AND molecules coding to hybrids polypeptides of different allergens from D. pteronyssinus useful for the prevention and treatment of allergies, particularly allergies caused by mites. Specifically, the invention describes hybrid proteins composed of fragments of allergens Derp p 1 y Derp p 2 with hypoallergenic characteristics and maintain their immunogenic capacity, being particularly useful for the treatment of allergy. The invention also describes the production methods of these polypeptides in heterologous expression systems. Besides, the invention describes efficient purification methods of these hybrid proteins.
    Type: Application
    Filed: February 9, 2015
    Publication date: June 4, 2015
    Applicant: BIAL INDUSTRIAL FARMACEUTICA, S.A.
    Inventors: Juan Andrés Asturias Ortega, Iñaki Ibarrola Lopez De Davalillo, Maria Carmen Arilla Rodriguez, Alberto Martinez Garate
  • Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies
    Patent number: 8951530
    Abstract: The present invention refers to recombinant ADN molecules coding to hybrids polypeptides of different allergens from D. pteronyssinus useful for the prevention and treatment of allergies, particularly allergies caused by mites. Specifically, the invention describes hybrid proteins composed of fragments of allergens Derp p 1 y Derp p 2 with hypoallergenic characteristics and maintain their immunogenic capacity, being particularly useful for the treatment of allergy. The invention also describes the production methods of these polypeptides in heterologous expression systems. Besides, the invention describes efficient purification methods of these hybrid proteins.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: February 10, 2015
    Assignee: Bial Industrial Farmaceutica, S.A.
    Inventors: Juan Andrés Asturias Ortega, Iñaki Ibarrola Lopez De Davalillo, Maria Carmen Arilla Rodriguez, Alberto Martinez Garate
  • HYPOALLERGENIC HYBRID PROTEINS OF MAJOR GROUP 1 AND 2 MITE ALLERGENS FOR USE IN THE TREATMENT OF ALLERGIES
    Publication number: 20110052640
    Abstract: The present invention refers to recombinant ADN molecules coding to hybrids polypeptides of different allergens from D. pteronyssinus useful for the prevention and treatment of allergies, particularly allergies caused by mites. Specifically, the invention describes hybrid proteins composed of fragments of allergens Derp p 1 y Derp p 2 with hypoallergenic characteristics and maintain their immunogenic capacity, being particularly useful for the treatment of allergy. The invention also describes the production methods of these polypeptides in heterologous expression systems. Besides, the invention describes efficient purification methods of these hybrid proteins.
    Type: Application
    Filed: March 24, 2009
    Publication date: March 3, 2011
    Applicant: BIAL INDUSTRIAL FARMACEUTICA, S.A.
    Inventors: Juan Andrés Asturias Ortega, Iñaki Ibarrola Lopez De Davalillo, Maria Carmen Arilla Rodriguez, Alberto Martinez Garate