Patents by Inventor Maria Carmen MULERO ROIG

Maria Carmen MULERO ROIG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL TARGETING CONSTRUCTS AND USES THEREOF
    Publication number: 20240269303
    Abstract: Cell-targeted cytotoxic compounds are provided herein. Such compounds can be used, e.g., to selectively bind and kill cancer cells such as cancer stem cells that express LGR4, LGR5, or LGR6. In some embodiments, the cytotoxic compounds include an LGR binding polypeptide, a cytotoxic agent (e.g., MMAE), and an Fc region (e.g., a mutant Fc domain). Methods for using the compounds to treat cell proliferative diseases such as cancers are also provided.
    Type: Application
    Filed: October 25, 2023
    Publication date: August 15, 2024
    Applicant: Research Development Foundation
    Inventors: Stephen HOWELL, Maria Carmen MULERO ROIG, Dennis P. GATELY