Patents by Inventor Maria Caterina Turco

Maria Caterina Turco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-BAG3 ANTIBODIES AS THERAPEUTIC REAGENT IN CARDIOVASCULAR DISEASE
    Publication number: 20220213182
    Abstract: The present invention relates to the use of anti-BAG3 antibodies and its pharmaceutical formulation in the treatment of cardiovascular diseases.
    Type: Application
    Filed: March 24, 2022
    Publication date: July 7, 2022
    Inventors: Maria Caterina TURCO, Liberato MARZULLO, Alessandra ROSATI, Margot DE MARCO, Anna BASILE
  • Anti-BAG3 antibodies for therapeutic use
    Patent number: 11117957
    Abstract: The present invention relates to the use of BAG3 antibodies as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic and/or degenerative nature.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: September 14, 2021
    Assignee: BIOUNIVERSA S.R.L.
    Inventor: Maria Caterina Turco
  • HUMANIZED ANTI-BAG3 ANTIBODIES
    Publication number: 20210122818
    Abstract: The present invention provides for a humanized anti-BAG3 antibody or a fragment thereof, pharmaceutical compositions comprising said antibody and its use as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic, cardiovascular and/or degenerative nature.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 29, 2021
    Inventors: Maria Caterina TURCO, Alessandra ROSATI, Vincenzo DE LAURENZI, Gianluca SALA
  • ANTI-BAG3 ANTIBODIES AS THERAPEUTIC REAGENT IN CARDIOVASCULAR DISEASE
    Publication number: 20210024623
    Abstract: The present invention relates to the use of anti-BAG3 antibodies and its pharmaceutical formulation in the treatment of cardiovascular diseases.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 28, 2021
    Inventors: Maria Caterina TURCO, Liberato MARZULLO, Alessandra ROSATI, Margot DE MARCO, Anna BASILE
  • Humanized anti-BAG3 antibodies
    Patent number: 10889644
    Abstract: The present invention provides for a humanized anti-BAG3 antibody or a fragment thereof, pharmaceutical compositions comprising said antibody and its use as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic, cardiovascular and/or degenerative nature.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: January 12, 2021
    Assignee: BIOUNIVERSA S.R.L.
    Inventors: Maria Caterina Turco, Alessandra Rosati, Vincenzo De Laurenzi, Gianluca Sala
  • ANTI-BAG3 ANTIBODIES IN COMBINATION WITH INHIBITORS OF IMMUNE CHECK-POINT FOR THERAPEUTIC USE
    Publication number: 20190263911
    Abstract: The present invention relates to a combination comprising anti-BAG3 antibodies and inhibitors of the immune check-point, to pharmaceutical formulation comprising said combination, optionally with an pharmaceutically acceptable excipient and to its use in the treatment of neoplastic diseases.
    Type: Application
    Filed: November 6, 2017
    Publication date: August 29, 2019
    Inventors: Maria Caterina TURCO, Vincenzo DE LAURENZI, Liberato MARZULLO, Alessandra ROSATI
  • BAG3 as biochemical serum and tissue marker
    Patent number: 10359433
    Abstract: The present invention concerns the field of diagnostic biological markers. Specifically the invention relates to anti-BAG3 antibodies for use as biological markers for the diagnosis of a pathological state. Furthermore, the invention involves specific ELISA methods and kits, for detecting and evaluating, anti-BAG3 antibodies or BAG3/antibody complexes in a biological sample.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: July 23, 2019
    Assignee: BIOUNIVERSA S.R.L.
    Inventor: Maria Caterina Turco
  • HUMANIZED ANTI-BAG3 ANTIBODIES
    Publication number: 20190153090
    Abstract: The present invention provides for a humanized anti-BAG3 antibody or a fragment thereof. pharmaceutical compositions comprising said antibody and its use as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic, cardiovascular and/or degenerative nature.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 23, 2019
    Inventors: Maria Caterina TURCO, Alessandra ROSATI, Vincenzo DE LAURENZI, Gianluca SALA
  • ANTI-BAG3 ANTIBODIES FOR THERAPEUTIC USE
    Publication number: 20190010221
    Abstract: The present invention relates to the use of BAG3 antibodies as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic and/or degenerative nature.
    Type: Application
    Filed: September 25, 2018
    Publication date: January 10, 2019
    Inventor: Maria Caterina TURCO
  • BAG3 receptor binding molecules for use as a medicament
    Patent number: 9963514
    Abstract: The present invention relates to the use of BAG3 receptor-binding molecules as a medicament, in particular for use in the treatment of diseases of an immune, inflammatory, cardiovascular, neoplastic and/or degenerative nature.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: May 8, 2018
    Assignee: BIOUNIVERSA S.R.L.
    Inventor: Maria Caterina Turco
  • Compounds modulators of VEGF activity and uses thereof
    Patent number: 9737622
    Abstract: Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: August 22, 2017
    Assignee: Advanced Accelerator Applications S.A.
    Inventors: Luca Domenico D'Andrea, Carlo Pedone, Maria Caterina Turco
  • BAG3 RECEPTOR BINDING MOLECULES FOR USE AS A MEDICAMENT
    Publication number: 20160168255
    Abstract: The present invention relates to the use of BAG3 receptor-binding molecules as a medicament, in particular for use in the treatment of diseases of an immune, inflammatory, cardiovascular, neoplastic and/or degenerative nature.
    Type: Application
    Filed: July 23, 2014
    Publication date: June 16, 2016
    Inventor: Maria Caterina TURCO
  • ANTI-BAG3 ANTIBODIES FOR THERAPEUTIC USE
    Publication number: 20150329622
    Abstract: The present invention relates to the use of BAGS antibodies as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic and/or degenerative nature.
    Type: Application
    Filed: March 4, 2014
    Publication date: November 19, 2015
    Applicant: BIOUNIVERSA S.R.L.
    Inventor: Maria Caterina TURCO
  • BAG3 AS BIOCHEMICAL SERUM AND TISSUE MARKER
    Publication number: 20150147767
    Abstract: The present invention concerns the field of diagnostic biological markers. Specifically the invention relates to anti-BAG3 antibodies for use as biological markers for the diagnosis of a pathological state. Furthermore, the invention involves specific ELISA methods and kits, for detecting and evaluating, anti-BAG3 antibodies or BAG3/antibody complexes in a biological sample.
    Type: Application
    Filed: December 16, 2014
    Publication date: May 28, 2015
    Inventor: Maria Caterina TURCO
  • BAG3 AS BIOCHEMICAL SERUM AND TISSUE MARKER
    Publication number: 20150132764
    Abstract: The present invention concerns the field of diagnostic biological markers. Specifically the invention relates to BAG3 RNA or a fragment thereof for use as biological markers for the diagnosis of a pathological state. Furthermore, the invention involves specific kits and methods, for detecting and/or evaluating the levels of BAG3 RNA or a fragment thereof in a biological sample.
    Type: Application
    Filed: December 16, 2014
    Publication date: May 14, 2015
    Inventor: Maria Caterina TURCO
  • COMPOUNDS MODULATORS OF VEGF ACTIVITY AND USES THEREOF
    Publication number: 20140341814
    Abstract: Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.
    Type: Application
    Filed: April 22, 2014
    Publication date: November 20, 2014
    Inventors: Luca Domenico D'Andrea, Carlo Pedone, Maria Caterina Turco
  • Compounds modulators of VEGF activity and uses thereof
    Patent number: 8741850
    Abstract: Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: June 3, 2014
    Assignee: Advanced Accelerator Applications S.A.
    Inventors: Luca Domenico D'Andrea, Carlo Pedone, Maria Caterina Turco
  • Biochemical serum marker
    Patent number: 8673585
    Abstract: The present invention relates to a method for detecting the presence and/or concentration of the soluble BAG3 protein in an unknown biological sample and the assay is preferably carried by ELISA assay with antibodies, preferably monoclonal antibodies. The presence of said protein in a soluble form is associated with heart disease or with the presence of pancreatic tumors.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: March 18, 2014
    Assignee: Biouniversa S.r.l.
    Inventor: Maria Caterina Turco
  • BIOCHEMICAL SERUM MARKER
    Publication number: 20120244561
    Abstract: The present invention relates to a method for detecting the presence and/or concentration of the soluble BAG3 protein in an unknown biological sample and the assay is preferably carried by ELISA assay with antibodies, preferably monoclonal antibodies. The presence of said protein in a soluble form is associated with heart disease or with the presence of pancreatic tumors.
    Type: Application
    Filed: December 3, 2010
    Publication date: September 27, 2012
    Applicant: Biounversa S.R.L.
    Inventor: Maria Caterina Turco
  • COMPOUNDS MODULATORS OF VEGF ACTIVITY AND USES THEREOF
    Publication number: 20120114565
    Abstract: Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 10, 2012
    Applicant: ADVANCED ACCELERATOR APPLICATIONS S.A.
    Inventors: Luca Domenico D'Andrea, Carlo Pedone, Maria Caterina Turco