Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: Disclosed herein are new cyclic dinucleotide compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulation of immune response to disease, and induce Stimulator of Interferon Genes (STING) dependent type I interferon production and co-regulated genes in a human or animal subject are also provided for the treatment diseases such as cancer, particularly metastatic solid tumors and lymphomas, inflammation, allergic and autoimmune disease, infectious disease, and for use as anti-viral agents and vaccine adjuvants.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material is provided that is stable in a wetting liquid and flushable in use. More particularly, multilayered structures including, but not limited to, two, three, or four layers are provided to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: Methods, systems, computer-readable media, and apparatuses for transfer of customer information between a first user interface and a third user interface by way of a second user interface are provided. In some embodiments, customer information may be imported into an intermediate user interface from a text-based user interface based on a first mapping associating portions of the text-based user interface with portions of an intermediate user interface. In some embodiments, the intermediate user interface is associated with a spreadsheet. The imported customer information may be reviewed by a user and accepted. The accepted customer information is used to populate a graphical user interface according to a second mapping associating one or more fields of the graphical user interface with portions of the intermediate user interface. In some embodiments, the graphical user interface is a browser-based user interface.

Abstract: The presently disclosed subject matter relates to a dispersible, nonwoven multistrata wipe material that is stable in a wetting liquid and flushable in use. More particularly, the presently disclosed subject matter relates to multilayered structures including, but not limited to, two, three, or four layers to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: A dispersible, nonwoven multistrata wipe material that is stable in a wetting liquid and flushable in use is provided. More particularly, the materials are multilayered structures including, but not limited to, two, three, or four layers to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: The presently disclosed subject matter relates to a dispersible, nonwoven multistrata wipe material that is stable in a wetting liquid and flushable in use. More particularly, the presently disclosed subject matter relates to multilayered structures including, but not limited to, two, three, or four layers to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: Methods, systems, computer-readable media, and apparatuses for transfer of customer information between a first user interface and a third user interface by way of a second user interface are provided. In some embodiments, customer information may be imported into an intermediate user interface from a text-based user interface based on a first mapping associating portions of the text-based user interface with portions of an intermediate user interface. In some embodiments, the intermediate user interface is associated with a spreadsheet. The imported customer information may be reviewed by a user and accepted. The accepted customer information is used to populate a graphical user interface according to a second mapping associating one or more fields of the graphical user interface with portions of the intermediate user interface. In some embodiments, the graphical user interface is a browser-based user interface.

Abstract: The current invention involves a dispersible, nonwoven multistrata wipe material that is stable in a wetting liquid and flushable in use. More particularly, the current invention involves multilayered structures including, but not limited to, two, three, or four layers to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.

Abstract: The presently disclosed subject matter relates to a dispersible, nonwoven multistrata wipe material that is stable in a wetting liquid and flushable in use. More particularly, the presently disclosed subject matter relates to multilayered structures including, but not limited to, two, three, or four layers to form the dispersible nonwoven wipe material. The layers contain combinations of cellulosic and noncellulosic fibers, and optionally a binder or additive.