Abstract: Systems and methods for removing clots via aspiration are disclosed herein. A catheter includes an elongate body defining a lumen. The distal region includes a distal openings region, a proximal openings region and a thrombus interface region between the distal and the proximal openings regions. The distal and proximal openings regions each includes one or more openings in fluid communication with the lumen. In use, the catheter is positioned from a proximal side of the clot so that the distal openings region positioned at least partially distal of the clot and the proximal openings region positioned at least partially proximal of the clot. An aspiration catheter is positioned with its distal end at the proximal end of the clot. The clot is then withdrawn in the proximal direction with a combination of aspiration applied to one or more of the catheter or the aspiration catheter.

Abstract: In some examples, a catheter includes an elongated body and an expandable member at a distal portion of the elongated body and defining at least part of a distal tip of the catheter. The expandable member includes a flexible membrane and an expandable ring or partial ring located at a distal portion of the expandable member, wherein the expandable ring or partial ring is configured to expand radially outward in response to electrical energy applied to the expandable ring or partial ring.

Abstract: a) The present invention falls within the area of the synthesis of ionic liquids, namely it concerns a process of synthesis of the ionic liquid tetraoctylammonium di(2-ethylhexyl)-oxamate (IL-5) with a high degree of purity and its use in the extraction and selective separation of metals, namely lanthanides. Thus, it is the object of the present invention, a process for the synthesis of a pure ionic liquid using in its constitution only the elements carbon, hydrogen, oxygen and nitrogen (CHON), assuming itself as a “green” alternative in the recovery of metals, thus reducing the environmental impact in the way they are recovered, as well as the guarantee of a more efficient extraction of these metals.

Abstract: In some examples, a catheter includes an elongated body and an expandable member at a distal portion of the elongated body and defining at least part of a distal tip of the catheter. The expandable member includes a flexible membrane and an expandable ring or partial ring located at a distal portion of the expandable member, wherein the expandable ring or partial ring is configured to expand radially outward in response to electrical energy applied to the expandable ring or partial ring.

Abstract: An aspiration catheter can be used to capture and retrieve vascular debris from blood vessels. The aspiration catheter can include a distal segment having ports positioned along its longitudinal length and about its circumference. The distal segment can capture thrombus at least partially on an exterior of the distal segment when aspiration is applied through the ports, and retrieve the thrombus when the elongate member is retracted proximally. The distal segment can be modified from a non-collapsed configuration to a collapsed configuration when aspiration is applied through the ports. The distal segment can have projections arranged along and around its circumference. The projections can be configured to slide distally through a thrombus within a blood vessel and to pull the thrombus when the elongate member is retracted proximally.

Abstract: In some examples, a catheter includes an elongated body extending between a proximal end and a distal end, and defining an inner lumen, an outer body wall having a wall cross-sectional diameter, and a distal aperture at the distal end. A distal portion of the elongated body including a taper section that tapers from the outer body wall of the distal portion to the distal aperture, with the distal portion defining a plurality of slits open to the distal aperture. The distal aperture has an aperture diameter greater than zero and less than the wall cross-sectional diameter. The distal portion defining the plurality of slits is configured to substantially center the distal end around a guide member when the guide member is introduced in the inner lumen and extends through the distal aperture.

Abstract: A medical device retrieval system can include an elongate core member and an expandable member coupled to a distal portion of the elongate core member. The expandable member can move between collapsed and expanded states. The expandable member has an exterior having barbs positioned therealong. The expandable member can be expanded to contact and engage a portion of a medical device positioned within the vasculature of a patient in order to retrieve and remove the medical device therefrom. When the expandable member moves to the collapsed state, it can move the medical device from a higher profile configuration to a lower profile configuration to facilitate retrieval.

Abstract: An aspiration catheter can be used to capture and retrieve vascular debris from blood vessels. The aspiration catheter can include a distal segment having ports positioned along its longitudinal length and about its circumference. The distal segment can capture thrombus at least partially on an exterior of the distal segment when aspiration is applied through the ports, and retrieve the thrombus when the elongate member is retracted proximally. The distal segment can be modified from a non-collapsed configuration to a collapsed configuration when aspiration is applied through the ports. The distal segment can have projections arranged along and around its circumference. The projections can be configured to slide distally through a thrombus within a blood vessel and to pull the thrombus when the elongate member is retracted proximally.

Abstract: A medical device retrieval system can include an elongate core member and an expandable member coupled to a distal portion of the elongate core member. The expandable member can move between collapsed and expanded states. The expandable member has an exterior having barbs positioned therealong. The expandable member can be expanded to contact and engage a portion of a medical device positioned within the vasculature of a patient in order to retrieve and remove the medical device therefrom. When the expandable member moves to the collapsed state, it can move the medical device from a higher profile configuration to a lower profile configuration to facilitate retrieval.

Abstract: In some examples, a catheter may include a catheter body configured such that at least one of a proximal portion or a medial portion of the catheter body has a cross-sectional shape including at least three apexes, adjacent apexes being connected by curvilinear sidewalls, the cross-section being taken substantially orthogonal to a longitudinal axis of the catheter body. In some examples, the entire catheter body has the cross-sectional shape including at least three apexes, adjacent apexes being connected by curvilinear sidewalls. In other examples, only a portion of the catheter body has the cross-sectional shape.

Abstract: In some examples, a catheter includes an elongated body extending between a proximal end and a distal end, and defining an inner lumen, an outer body wall having a wall cross-sectional diameter, and a distal aperture at the distal end. A distal portion of the elongated body including a taper section that tapers from the outer body wall of the distal portion to the distal aperture, with the distal portion defining a plurality of slits open to the distal aperture. The distal aperture has an aperture diameter greater than zero and less than the wall cross-sectional diameter. The distal portion defining the plurality of slits is configured to substantially center the distal end around a guide member when the guide member is introduced in the inner lumen and extends through the distal aperture.

Abstract: A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.

Abstract: A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.