Abstract: The present disclosure is related to apparatuses, processes, and extrusion screws directed to process solid detergent compositions in shapes like billets, bars, tablets, noodles, and similar shapes produced from extruded synthetic detergents, soaps, and combinations thereof. The present disclosure describes an extrusion screw for processing synthetic detergents, soaps, and combinations thereof. The extrusion screw comprises a feed section, a metering section, and a compression section. Said compression section has a proximal channel depth adjacent to the feed section, and a distal channel depth adjacent to the metering section, and a compression ratio that may be between 2.2, and 4.1, for example, between 2.2, and 2.6. The extrusion screw may have a length to diameter ratio (L/D) that may be between 4.0, and 6.0. The present disclosure also describes an apparatus for processing synthetic detergents, soaps, and combinations thereof. The apparatus comprises a barrel and said extrusion screw.

Abstract: The invention provides a composition rich in flavonoids based on natural extracts, comprising a flavonoid extract dispersed by melt mixing or extrusion and encapsulated in a polymer matrix. The invention is also a novel dietary supplement with the naturally occurring ingredient (?)-epicatechin, cacao extracted, that could potentially prevent or reduce the risk of Atherosclerotic pathology. The use of (?)-epicatechin is promising as a therapeutic agent due to its potential antioxidant activity and its diverse biological properties. (?)-Epicatechins are chemically unstable and extensively degraded in fluids of near neutral or greater pH, such as intestinal juice and bile. Current technologies used for taste masking and modified release as spray drying, liposome entrapment, co-crystallization, freeze drying, among others, suffer from numerous shortcomings, including poor repeatability and limitations on target delivery.

Abstract: The invention provides a composition rich in flavonoids based on natural extracts, comprising a flavonoid extract dispersed by melt mixing or extrusion and encapsulated in a polymer matrix. The invention is also a novel dietary supplement with the naturally occurring ingredient (?)-epicatechin, cacao extracted, that could potentially prevent or reduce the risk of Atherosclerotic pathology. The use of (?)-epicatechin is promising as a therapeutic agent due to its potential antioxidant activity and its diverse biological properties. (?)-Epicatechins are chemically unstable and extensively degraded in fluids of near neutral or greater pH, such as intestinal juice and bile. Current technologies used for taste masking and modified release as spray drying, liposome entrapment, co-crystallization, freeze drying, among others, suffer from numerous shortcomings, including poor repeatability and limitations on target delivery.

Abstract: The invention provides a composition rich in flavonoids based on natural extracts, comprising a flavonoid extract dispersed by melt mixing or extrusion and encapsulated in a polymer matrix. The invention is also a novel dietary supplement with the naturally occurring ingredient (?)-epicatechin, cacao extracted, that could potentially prevent or reduce the risk of Atherosclerotic pathology. The use of (?)-epicatechin is promising as a therapeutic agent due to its potential antioxidant activity and its diverse biological properties. (?)-Epicatechins are chemically unstable and extensively degraded in fluids of near neutral or greater pH, such as intestinal juice and bile. Current technologies used for taste masking and modified release as spray drying, liposome entrapment, co-crystallization, freeze drying, among others, suffer from numerous shortcomings, including poor repeatability and limitations on target delivery.

Abstract: The dissolution of Active Pharmaceutical Ingredients in polymeric melts plays an important role in the manufacturing of drugs that use polymers as excipients. The dissolution kinetics is essential for designing the processing equipment, describing the operating conditions, and defining material properties, for example, the appropriate API-polymer(s) pair. In one embodiment of the invention, the solubility of ketoprofen (KTO) in Soluplus®, Kollidon® VA64, Kollidon® SR and a combination of three; was analyzed under Hot Melt Extrusion (HME) processing conditions. Thermal characterization techniques show that a single phase amorphous solid solution (only one Tg) was achieved by HME at 120° C. and 70 rpm. The sample's stability was analyzed for 4 weeks and the single phase amorphous solid solution was maintained during that time. An extended release profile of KTO was achieved, releasing 100% of KTO in 12 h. The invention is particularly useful to target a specific release profile.

Abstract: The invention relates to a device for diverting the flight of birds in order to prevent collisions with overhead wires and cables, such as high-voltage lines. The inventive device comprises a system for fixing same to overhead wires and cables, from which a central body is suspended. The fixing system enables the device to be mounted to or removed from overhead wires and cables of different diameters manually by one person. The diversion device comprises a modular construction, thereby facilitating the transport thereof and the replacement of any part if necessary. Once assembled, the volume of the device is greater than that of the individual parts. All of the device is made form an electrically-insulating polymer material which does not corrode the cables or wires. Moreover, the device can move and the components thereof can have different colors in order to render same more visible. In addition, the components of the device are perforated such as to have low wind resistance.

Abstract: The invention relates to a device for diverting the flight of birds in order to prevent collisions with overhead wires and cables, such as high-voltage lines. The inventive device comprises a system for fixing same to overhead wires and cables, from which a central body is suspended. The fixing system enables the device to be mounted to or removed from overhead wires and cables of different diameters manually by one person. The diversion device comprises a modular construction, thereby facilitating the transport thereof and the replacement of any part if necessary. Once assembled, the volume of the device is greater than that of the individual parts. All of the device is made form an electrically-insulating polymer material which does not corrode the cables or wires. Moreover, the device can move and the components thereof can have different colours in order to render same more visible. In addition, the components of the device are perforated such as to have low wind resistance.

Abstract: A device to visualize in-line the polymer melting in plasticating screw machines has an external metallic cylinder to be fixed in radial position regarding the barrel of the plasticating machine, a bushing with an optical window clear to the visible light spectrum resistant to pressure and temperature positioned in such a way that its external face is tangent to the internal surface of the barrel of the plasticating machine, and an internal metallic cylinder to guide the coolant gas and allow the use of an observation probe with operating temperature limits and an illumination system.

Abstract: A device to visualize in-line the polymer melting in plasticating screw machines has an external metallic cylinder to be fixed in radial position regarding the barrel of the plasticating machine, a bushing with an optical window clear to the visible light spectrum resistant to pressure and temperature positioned in such a way that its external face is tangent to the internal surface of the barrel of the plasticating machine, and an internal metallic cylinder to guide the coolant gas and allow the use of an observation probe with operating temperature limits and an illumination system.