Patents by Inventor Maria Di Marzo

Maria Di Marzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives having antitumor activity
    Patent number: 8053460
    Abstract: Indole derivatives of Formula (I+A) having antitumor and chemosensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumors.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: November 8, 2011
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino
  • Synthesis of deoxybiotinyl hexamethylenediamine-dota
    Patent number: 7851621
    Abstract: A process for the synthesis of deoxybiotinyl hexamethylenediamine0-DOTA is herein described. Said process comprises reacting biotinyl hexamithylenediamine with tri-t-butyl DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as a base.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: December 14, 2010
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Mauro Marzi, Maria Di Marzo
  • Cinnamic, phenylpropiolic and phenylpropanoic acid derivatives useful as anti-tumor agents
    Patent number: 7816386
    Abstract: Cinnamic and phenylpropiolic acid derivatives of formula (I) having antitumour and chemo sensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: October 19, 2010
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino, Riccardo Pezzi
  • SYNTHESIS OF DEOXYBIOTINYL HEXAMETHYLENEDIAMINE-DOTA
    Publication number: 20100184972
    Abstract: A process for the synthesis of deoxybiotinyl hexamethylenediamine0-DOTA is herein described. Said process comprises reacting biotinyl hexamithylenediamine with tri-t-butyl DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as a base.
    Type: Application
    Filed: May 31, 2006
    Publication date: July 22, 2010
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Mauro Marzi, Maria Di Marzo
  • Indole Derivatives Having Antitumor Activity
    Publication number: 20080207729
    Abstract: Indole derivatives of Formula (I+A) having antitumour and chemosensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.
    Type: Application
    Filed: May 31, 2006
    Publication date: August 28, 2008
    Applicant: SIGMA-TAU FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino
  • Cinnamic, Phenylpropiolic and Phenylpropanoic Acid Derivatives Useful as Anti-Tumor Agents
    Publication number: 20080194659
    Abstract: Cinnamic and phenylpropiolic acid derivatives of formula (I) having antitumour and chemo sensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.
    Type: Application
    Filed: May 31, 2006
    Publication date: August 14, 2008
    Applicant: SIGMA-TAU FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino, Ricaardo Pezzi