Patents by Inventor Maria-Elena Theoclitou

Maria-Elena Theoclitou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 10301267
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: May 28, 2019
    Assignee: AstraZeneca AB
    Inventors: David Buttar, Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • NOVEL COMPOUNDS
    Publication number: 20170260143
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: May 26, 2017
    Publication date: September 14, 2017
    Inventors: David BUTTAR, Kevin Michael FOOTE, Maria-Elena THEOCLITOU, Andrew Peter THOMAS
  • Methods of treating cancer with a pyrazole derivative
    Patent number: 9688640
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: June 27, 2017
    Assignee: ASTRAZENECA AB
    Inventors: David Buttar, Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • NOVEL COMPOUNDS
    Publication number: 20150299134
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: June 26, 2015
    Publication date: October 22, 2015
    Applicant: AstraZeneca AB
    Inventors: David BUTTAR, Kevin Michael FOOTE, Maria-Elena THEOCLITOU, Andrew Peter THOMAS
  • NOVEL COMPOUNDS
    Publication number: 20140066455
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: November 13, 2013
    Publication date: March 6, 2014
    Applicant: AstraZeneca AB
    Inventors: David BUTTAR, Kevin Michael FOOTE, Maria-Elena THEOCLITOU, Andrew Peter THOMAS
  • N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl]-4-(3,4-dimethylpiperazin-1-yl)benzamide and salts thereof
    Patent number: 8604022
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: December 10, 2013
    Assignee: AstraZeneca AB
    Inventors: Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas, David Buttar
  • N-[5-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-3-YL]-4-(3,4-DIMETHYLPIPERAZIN-1-YL)BENZAMIDE AND SALTS THEREOF
    Publication number: 20120129844
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: January 26, 2012
    Publication date: May 24, 2012
    Inventors: David Buttar, Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-(3,4-dimethylpiperazin-1-yl)benzamide and salts thereof
    Patent number: 8129391
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: March 6, 2012
    Assignee: AstraZeneca AB
    Inventors: Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas, David Buttar
  • N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-(3,4-dimethylpiperazin-1-yl)benzamide and Salts Thereof
    Publication number: 20100273811
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: April 30, 2010
    Publication date: October 28, 2010
    Inventors: David Buttar, Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof
    Patent number: 7737149
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: June 15, 2010
    Assignee: AstraZeneca AB
    Inventors: David Buttar, Kevin Michael Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • PYRAZOLE COMPOUNDS 436
    Publication number: 20090318468
    Abstract: There is provided novel compounds of formula (Ia) or (Ib): or pharmaceutically acceptable salsts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: June 19, 2009
    Publication date: December 24, 2009
    Applicant: AstraZeneca AB
    Inventors: David Buttar, Maria-Elena Theoclitou, Andrew Peter Thomas
  • ENANTIOMERS OF SELECTED FUSED HETEROCYCLICS AND USES THEREOF
    Publication number: 20090099210
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 16, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Ann Filla, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Enantiomers of selected fused heterocyclics and uses thereof
    Patent number: 7498333
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: March 3, 2009
    Assignee: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Ann Filla, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • NOVEL FUSED HETEROCYCLES AND USES THEREOF
    Publication number: 20080153854
    Abstract: This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: February 15, 2008
    Publication date: June 26, 2008
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Filla, Richard William Luke, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • NOVEL COMPOUNDS
    Publication number: 20080153812
    Abstract: There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
    Type: Application
    Filed: December 18, 2007
    Publication date: June 26, 2008
    Applicant: ASTRAZENECA AB
    Inventors: David Buttar, Kevin Micheal Foote, Maria-Elena Theoclitou, Andrew Peter Thomas
  • Novel Compounds
    Publication number: 20080004302
    Abstract: There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Maria-Elena Theoclitou, David Buttar, Kevin Michael Foote, Thorsten Nowak, David Alan Rudge, Andrew Peter Thomas
  • Novel fused heterocycles and uses thereof
    Publication number: 20060063751
    Abstract: This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: March 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Filla, Richard Luke, Timothy Pontz, Daniel Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Enantiomers of selected fused heterocyclics and uses thereof
    Publication number: 20060041129
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: February 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Selected fused heterocyclics and uses thereof
    Publication number: 20060041128
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: February 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel Russell, Maria-Elena Theoclitou, XiaoLan Zheng