Abstract: There is provided is provided a computer program product, comprising instructions which, when executed by a processing unit, cause the processing unit to carry out a method for controlling a respiratory support device to provide a pressurized airflow to a subject. The method comprises the steps of receiving a respiratory signal representative of respiratory information of the subject, determining at least one of a hypoxia and a hypercapnia based on the respiratory signal, and providing a control signal to the respiratory support device in response to determining the at least one of a hypoxia and a hypercapnia. Further, there is provided a respiratory support device for providing a pressurized airflow to a subject.

Abstract: Disclosed herein is a medical instrument (100) comprising a magnetic resonance imaging system (102) configured for acquiring k-space data (148, 152, 166) of a brain of a subject (118) with a missing limb (128) and a complementary limb (129) and a virtual reality system (122). The execution of machine executable instructions causes a computational system (132) to: identify (210) a complementary limb functional region (156) using functional magnetic resonance imaging and determine (212) a phantom limb functional region (158) in the brain by applying brain symmetry.

Abstract: In order to improve MRI workflow, a recommender system is provided that comprises an input unit, a processing unit, and an output unit. The input unit is configured to receive data comprising information about a plurality of pre-tests provided to a patient and associated pre-test results. The plurality of pre-tests is performed prior to an MRI scan session. The plurality of pre-tests comprises a cognitive test, a sensorimotor test, or a combination thereof. The processing unit is configured to generate, based on the received data, a cognitive profile of the patient indicative of an individual's pattern of relative strengths and difficulties across several cognitive domains. The processing unit is further configured to determine, based on the cognitive profile of the patient, a task implementation for the MRI scan session. The processing unit is further configured to provide, via the output unit, a recommendation of the determined task implementation for the MRI scan session.

Abstract: A method and apparatus for use as part of diagnostic analysis of the psychiatric or neurological health of a patient based on use of a normative database of fMRI data results and cognitive task results for a population of prior patients. Embodiments propose to acquire fMRI data of a particular set of one or more regions of the brain of a patient while the patient is performing a cognitive task, and to record at the same time results of the patient's performance in the cognitive task. A combination of both the cognitive task results and the fMRI data for the brain regions is used to provide an indicator as to a cognitive health status of the patient. More particularly, a normative database of fMRI data results and cognitive task results for a population of patients is used as a reference. This may store results both for healthy patients and pathological patients, to provide a normal and abnormal reference.

Abstract: A system and method for determining a correlation between medication intake and sleep disordered breathing, SDB, therapy outcome for a subject taking at least one type of medication and being provided with SDB therapy. The SDB therapy comprises at least positive airway pressure, PAP, therapy provided by a PAP device. Medication information, relating to a medication intake of the subject, and SDB therapy information, relating to a therapy outcome of the SDB therapy, are obtained and correlated.

Abstract: The present invention relates to a method (10) for monitoring the performance of a predetermined test task executed by a subject during an fMRI examination. The method comprises acquiring (11) a timeseries of fMRI images and providing (12) a sensory stimulus to the subject during the acquisition in accordance with the predetermined test task. The method comprises determining (13), after the sensory stimulus, an activity measure indicative of brain activity in at least one predetermined region of interest, and generating (14) at least one signal when the activity measure is indicative of a poor performance of and/or compliance to the predetermined test task. The signal is generated during the acquisition of the time series and/or before removing the subject from the magnetic resonance imaging system. Further aspects of the invention relate to computer program products, computer systems and MRI systems.

Abstract: A system and method for controlling rhythmic sensory stimulation provided to a subject with post-stroke depression, PSD, during an MRI scan. A control unit is configured to control a rhythmic sensory stimulation signal such that the signal is rhythmically synchronous to a scanning rhythm of an MRI scanner performing the MRI scan.

Abstract: According to an aspect, there is provided a computer-implemented method for determining a sleep schedule (20; 40; 60) for a subject. The method comprises obtaining (101) information indicating a shift working pattern for the subject, the shift working pattern comprising at least one night shift, information indicating a required duration of sleep for the subject, and information relating to any personal activities to be undertaken by the subject during the day before or day after the at least one night shift. The method also comprises analyzing (103) the obtained information to determine a sleep schedule (20; 40; 60) for the subject. The sleep schedule (20; 40; 60) comprises two or more sleep windows in the day before or day after the at least one night shift in which the subject is to sleep, with the two or more sleep windows being scheduled according to the required duration of sleep for the subject and according to any personal activities to be undertaken by the subject.

Abstract: A system provides a trigger signal for controlling the operation of a scanner. A laser speckle vibrometry system is used for non-contact vibration sensing. A patient coil arrangement is provided for mounting adjacent (e.g. fixing to) a body of a patient and it comprises at least one window enabling passage of the laser light of the optical system to the body of the patient. The detected reflected laser light (through the window) is processed to detect the cardiac cycle and to generate a cardiac trigger signal for the control of the scanner.

Abstract: Disclosed herein is a medical instrument (100, 300) comprising an activity measurement system (110, 301, 302) configured for measuring brain activity data (136) from a subject (102), a memory (120) storing machine executable instructions (130) and storing a simulation model (132), wherein the simulation model is configured to generating simulation data (134), wherein the simulation model is configured for modifying the simulation data using a model parameter (140), a virtual reality system (106, 106?, 106?, 106??, 106??) configured for rendering the simulation data; and a computational system (114) for controlling the medical instrument. Execution of the machine executable instructions causes the computational system to set (200) the model parameter to an initial value (142).

Abstract: The present invention relates to attention bias modification treatment. In order to improve the treatment effect, an ABM system is proposed with a neural brain response monitoring device, such as functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), and/or electroencephalography (EEG), to provide real-time information regarding neural brain responses in order to personalize and optimize the ABM treatment.

Abstract: A system and method for analyzing the brain activity of a subject during a transition between brain states. Brain activity data including data representative of a transition between brain states is received from a brain monitoring system and processed to obtain a value for one or more transition parameters. The one or more transition parameters are parameters that characterize the transition between brain states and may be used as a biomarker for identifying mental disorders.

Abstract: The present invention relates to an apparatus (10) for determining and/or assessing depression severity of a patient. The apparatus comprising: an input unit (20); an image display unit (30); at least one sensor (40); and a processing unit (50). The image display unit is configured to present a plurality of images to a patient and the plurality of images are of different human facial expressions. The at least one sensor is configured to acquire information relating to the patients viewing of the plurality of images. The input unit is configured to provide the processing unit with the information relating to the patients viewing of the plurality of images. The input unit is configured to provide the processing unit with MRI scan image data of the patient. The MRI scan image data of the patient comprises MRI scan image data of at least one part of the patients brain associated with recognition of facial expressions and/or associated with affective disorders.

Abstract: It is proposed to obtain information about a stress or anxiety level of a subject within a predetermined time period before, during and/or after a capture time of a fMRI scan image. Using this information, embodiments may provide additional/supplementary information that may aid, assist or otherwise improve interpretation of the fMRI scan image.

Abstract: A system comprises a first sensor for generating a swelling signal based on the user pressing on the first sensor with a body part, a second sensor for generating a blood signal which is indicative of the volume of blood in the body part when the user presses on the first sensor and a force sensor for measuring the force applied by the body part to the first sensor when the user presses on the first sensor. The system also comprises a processor configured to determine an indication of swelling for the body part based on the swelling signal when the force sensor measures a first pre-determined value, determine an indication of blood pressure at the body part based on a force value measured by the force sensor when the blood signal reaches a second pre-determined value.

Abstract: A system for unobtrusively determining a fertile window includes a contact sensor in contact with the woman and configured to provide a signal indicative of respiration of the woman. A processor is configured to process the signal to obtain a biomechanical parameter indicative of the respiration, and determine the fertile window of the woman based on a change in the obtained biomechanical parameter.

Abstract: Two subsequent fMRI images taken during or around an EMDR therapy treatment are compared. A change in a trauma level metric in relevant brain anatomy of a traumatized patient is determined and communicated, such that the success of the EMDR therapy can be more objectively assessed and/or the information may be used to tailor the EMDR therapy a during or after a therapy session.

Abstract: The present invention relates to sleepiness assessment. In order to provide a more accurate measure to predict OSA severity, an apparatus is provided for sleepiness assessment. The apparatus comprises an input unit, a processing unit, and an output unit. The input unit is configured to receive data indicative of an activity currently performed by a user. The processing unit is configured to determine, based on the activity currently performed by the user, a current situation the user is engaging in. The processing unit is configured to determine whether the current situation matches one of a plurality of pre-determined situations used for situational sleepiness assessment. In response to the determination that the current situation matches one of the plurality of predetermined situations, the processing unit is configured to send a notification to the user for a self-report of a user's current subjective sleepiness level and/or obtain a user's current objective sleepiness level from sensor data.

Abstract: The present invention relates to an agenda generation system (10), comprising: at least one first sensor unit (20); an input unit (30); a processing unit (40); and at least one output unit (50); wherein the at least one first sensor unit is configured to acquire physiological data of a subject over an extended period of time prior to a current time point and provide the physiological data to the processing unit, wherein the physiological data is assigned to different times during the extended period of time, and wherein the physiological data comprises one or more of: heart rate, ventricular high rate, blood pressure, respiration rate, skin conductance, step count; wherein the at least one first sensor unit is configured to acquire sleep data of the subject over the extended period of time and provide the sleep data to the processing unit, wherein the sleep data is assigned to different times during the extended period of time, and wherein the sleep data comprises one or more of: duration of sleep; total d

Abstract: The present invention relates to a device (100), system (500) and method for determining SpO2 (160) of a subject. Two types of PPG measurements, widefield PPG with a homogenous illumination and/or a spot pattern and radial PPG with a spot illumination, are used to quantify the discrepancy in penetration depths for electromagnetic radiation in the red spectral range and infrared spectral range. This discrepancy in penetration depth is then used to find a more stable ratio signals of ratios, RR, and thus a more accurate SpO2 (160).