Patents by Inventor Maria-Fatima Grossi de Sa
Maria-Fatima Grossi de Sa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11525143Abstract: Described are methods for promoting increase in plant biomass and yield. This increase has its visible effects in organs such as leaf, stem, root and production of fruits and seeds. Further described is the increase in tolerance of those plants to drought, generating plants better adapted to the environmental changes, improving their growth, biomass and yield.Type: GrantFiled: May 4, 2020Date of Patent: December 13, 2022Assignee: Universidade Federal Do Rio De JaneiroInventors: Adriana Silva Hemerly, Paulo Cavalcanti Gomes Ferreira, Pan Gong, Hilde Nelissen, Dirk Inzé, Maria Fatima Grossi De Sá, Marcos Fernando Basso, Carolina Vianna Morgante, Maria Eugenia Lisei-De-Sa
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Publication number: 20210315214Abstract: The present invention relates to a process for manufacturing chitosan nanoparticles. The chitosan nanoparticles have dsRNAst adhered onto the surface of the particles. The dsRNAst is selected to have the property to gene silencing of AgraChSII. The invention does also relate to the chitosan nanoparticle, its use in pest-control, as pesticide, and a concentrated suspension containing the chitosan nanoparticles.Type: ApplicationFiled: July 3, 2018Publication date: October 14, 2021Applicants: INL - International Iberian Nanotechnology Laboratory, EmbrapaInventors: Maria Fátima GROSSI DE SA, Leonardo Lima PEPINO DE MACEDO, Maria Christina Mattar SILVA, Rayssa Almeida GARCIA, Luciano DA SILVA PAULINO, Ana VILA
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Patent number: 10975386Abstract: The present invention relates to the control of pest infestation by inhibiting or reducing the expression of genes of the family of chitin synthase and of vitellogenin, as well as through the expression of the toxin Cry8ka5. The invention further provides method and compositions for controlling pests, by feeding the pest with one or more double-stranded RNA molecules provided by the present invention, as well as double-stranded RNA molecule provided by the present invention, as well as through the action of the toxin Cry8ka5 on the target insect. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules and the toxin protein Cry8ka5. The present invention is preferably used for cotton plants.Type: GrantFiled: December 18, 2014Date of Patent: April 13, 2021Assignees: EMBRAPA EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA, FUNDAÇÃO UNIVERSIDADE DE BRASÍLIA—FUB—UNBInventors: Maria Fátima Grossi De Sa, Roberta Ramos Coelho, Alexandre Augusto Pereira Fimino, Leonardo Lima Pepino De Macedo, Maria Cristina Mattar Da Silva, Isabela Tristan Lourenço, José Dijair Antonino De Souza Júnior
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Patent number: 10941387Abstract: The present invention relates to the field of insect pests control, using methods and compositions which comprise of alpha-amylase analogous mutant inhibitors (?AIs). More specifically, the invention provides new ?AIs analogous mutant molecules for controlling insect pests, in particular boll weevils (Anthonomus grandis), partially or totally presenting reduction of the amylolytic activity of the digestive enzymes in the intestinal lumen of the insect. Other aspects of the invention include gene constructs containing the nucleic acid molecules that code for the alpha-amylase inhibitors, heterologous expression methods of the new molecules in the active form, and the use of these molecules for controlling insect pests. The invention also provides analogous synthetic genes optimized for their transformation and expression in plants.Type: GrantFiled: June 8, 2012Date of Patent: March 9, 2021Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPAInventors: Maria Fatima Grossi De Sa, Maria Cristina Mattar Da Silva, Rafael Perseguini Del Sarto, Thales Lima Rocha
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Publication number: 20200347399Abstract: Described are methods for promoting increase in plant biomass and yield. This increase has its visible effects in organs such as leaf, stem, root and production of fruits and seeds. Further described is the increase in tolerance of those plants to drought, generating plants better adapted to the environmental changes, improving their growth, biomass and yield.Type: ApplicationFiled: May 4, 2020Publication date: November 5, 2020Inventors: Adriana Silva Hemerly, Paulo Cavalcanti Gomes Ferreira, Pan Gong, Hilde Nelissen, Dirk Inzé, Maria Fatima Grossi De Sá, Marcos Fernando Basso, Carolina Vianna Morgante, Maria Eugenia Lisei-De-Sa
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Patent number: 10822609Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.Type: GrantFiled: December 27, 2013Date of Patent: November 3, 2020Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do SulInventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
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Patent number: 10704055Abstract: The proposed innovation relates to the biotechnological improvement of plant species of commercial interest. More specifically, the present invention relates to the production of transgenic plants biotechnological with greater tolerance to water deficit and salt stress by means of the expression of a new gene of coffee (of the Coffea Arabica species), belonging to the HD-Zip family, and characterized by a homeodomain associated with a leucine zipper. The expression of this transcriptional factor is induced in leaves and roots of coffee plants subjected to various water deficit conditions (both moderate and severe); transgenic plants that over-express this gene inhibiting greater tolerance both to differ drought intensities and to high salt concentrations.Type: GrantFiled: November 8, 2011Date of Patent: July 7, 2020Assignees: UNIVERSIDADE FEDERAL DO RIO DE JANEIRO, EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPAInventors: Marcio Alves Ferreira, Fernanda Pinheiro Da Cruz Waltenberg, Eduardo Romano De Campos Pinto, Maria Fatima Grossi De Sa
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Patent number: 10687529Abstract: The present application relates generically to compositions used for controlling agricultural pests and, in a particular, to compositions usable for combating nematodes. The application presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative includes a nematotoxic composition for controlling nematodes that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.Type: GrantFiled: December 26, 2013Date of Patent: June 23, 2020Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA-EMBRAPA, THE UNIVERSITY OF MELBOURNEInventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair Dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
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Patent number: 10647993Abstract: The present invention belongs to an insecticide compound derived from a strain of Bacillus thuringiensis and refers to the field of controlling plant pests, particularly to the control of the boll weevil—Anthonomus grandis. More specifically, the object of the invention refers to a new gene for the new delta-endotoxin designated Cry8Ha and to the cloning and expression of the gene that encodes for the protein Cry8Ha in Escherichia coli. There is provided the nucleotide sequence and encoding protein of the new delta-endotoxin, recombinant vectors and host cells. There is also provided processes and means for recombinant production and the use of the new delta-endotoxin for application in the control of the boll weevil. Additionally, the invention also provides an optimized synthetic gene for expression in cotton plants. Using the gene described herein, it is possible to transform plants based on techniques known by specialists in the art, for the expression of the endotoxin active against the boll weevil.Type: GrantFiled: July 26, 2010Date of Patent: May 12, 2020Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPAInventors: Maria Fatima Grossi De Sa, Gustavo Ramos De Oliveira, Maria Cristina Mattar Da Silva, Thales Lima Rocha, Mariana Torquato Quezado De Magalhaes
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Patent number: 10182571Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-stranded RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules. The present invention is preferably used for cotton-plants.Type: GrantFiled: December 27, 2013Date of Patent: January 22, 2019Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPAInventors: Maria Fátima Grossi de Sá, Maria Cristina Mattar Da Silva, Leonardo Lima Pepino de Macedo, Alexandre Augusto Pereira Firmino, Roberta Ramos Coelho, Isabela Tristan Lourenço
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Patent number: 9750247Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.Type: GrantFiled: December 26, 2013Date of Patent: September 5, 2017Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA-EMBRAPA, UNITVERSITY OF MELBOURNEInventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
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Publication number: 20170029843Abstract: The present invention relates to the control of pest infestation by inhibiting or reducing the expression of genes of the family of chitin synthase and of vitellogenin, as well as through the expression of the toxin Cry8ka5. The invention further provides method and compositions for controlling pests, by feeding the pest with one or more double-stranded RNA molecules provided by the present invention, as well as double-stranded RNA molecule provided by the present invention, as well as through the action of the toxin Cry8ka5 on the target insect. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules and the toxin protein Cry8ka5. The present invention is preferably used for cotton plants.Type: ApplicationFiled: December 18, 2014Publication date: February 2, 2017Applicants: Embrapa - Empresa Brasileira de Pesquisa Agropecuária, Fundação Universidade de Brasília - FUB - UnBInventors: Maria Fátima GROSSI DE SA, Roberta RAMOS COELHO, Alexandre Augusto PEREIRA FIMINO, Leonardo LIMA PEPINO DE MACEDO, Maria Cristina MATTAR DA SILVA, Isabela TRISTAN LOURENÇO
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Publication number: 20160000086Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-stranded RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules. The present invention is preferably used for cotton-plants.Type: ApplicationFiled: December 27, 2013Publication date: January 7, 2016Applicant: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA- EMBRAPAInventors: Maria Fátima Grossi de Sá, Maria Cristina Mattar Da Silva, Leonardo Lima Pepino de Macedo, Alexandre Augusto Pereira Firmino, Roberta Ramos Coelho, Isabela Tristan Lourenço
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Publication number: 20150368649Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.Type: ApplicationFiled: December 27, 2013Publication date: December 24, 2015Applicant: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SULInventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
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Publication number: 20150313220Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.Type: ApplicationFiled: December 26, 2013Publication date: November 5, 2015Applicants: THE UNIVERSITY OF MELBOURNE, EMPRESA BRASIL EIRA DE PESQUISA AGROPECUARIA- EMBRAPAInventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
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Publication number: 20150313216Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.Type: ApplicationFiled: December 26, 2013Publication date: November 5, 2015Applicants: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA- EMBRAPA, THE UNIVERSITY OF MELBOURNEInventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair Dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
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Patent number: 9012720Abstract: A polynucleotide isolated from soybean plants capable of initiating transcription and with sequence identity to SEQ ID No. 1 is provided. In some aspects, the polynucleotide has sequence identity to SEQ ID No. 1 of at least 40%, is the reverse complement or the reverse of such sequences. In some aspects, the polynucleotide is linked to expression enhancers or sequences of interest. In some embodiments, a recombinant vector comprises the polynucleotide. In some aspects, the recombinant vector comprises enhancers, termination sequences, or sequences of interest. In some embodiments a transformed cell, plant, plant part, or propagulum comprise the polynucleotide.Type: GrantFiled: February 19, 2013Date of Patent: April 21, 2015Assignee: Empresa Brasileira de Pesquisa AgropecuariaInventors: Maria Fatima Grossi de Sa, Luciane Mourao Guimaraes, Joao Aguiar Nogueira Batista, Antonio Americo Barbosa Viana, Rodrigo da Rocha Fragoso, Maria Cristina Mattar da Silva
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Publication number: 20140366217Abstract: The present invention relates to the field of insect pests control, using methods and compositions which comprise of alpha-amylase analogous mutant inhibitors (?AIs). More specifically, the invention provides new ?AIs analogous mutant molecules for controlling insect pests, in particular boll weevils (Anthonomus grandis), partially or totally presenting reduction of the amylolytic activity of the digestive enzymes in the intestinal lumen of the insect. Other aspects of the invention include gene constructs containing the nucleic acid molecules that code for the alpha-amylase inhibitors, heterologous expression methods of the new molecules in the active form, and the use of these molecules for controlling insect pests. The invention also provides analogous synthetic genes optimized for their transformation and expression in plants.Type: ApplicationFiled: June 8, 2012Publication date: December 11, 2014Applicant: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA - EMBRAPAInventors: Maria Fatima Grossi De Sa, Maria Cristina Mattar Da Silva, Rafael Perseguini Del Sarto, Thales Lima Rocha
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Publication number: 20130340113Abstract: The proposed innovation relates to the biotechnological improvement of plant species of commercial interest. More specifically, the present invention relates to the production of transgenic plants biotechnological with greater tolerance to water deficit and salt stress by means of the expression of a new gene of coffee (of the Coffea Arabica species), belonging to the HD-Zip family, and characterized by a homeodomain associated with a leucine zipper. The expression of this transcriptional factor is induced in leaves and roots of coffee plants subjected to various water deficit conditions (both moderate and severe); transgenic plants that over-express this gene inhibiting greater tolerance both to differ drought intensities and to high salt concentrations.Type: ApplicationFiled: November 8, 2011Publication date: December 19, 2013Applicant: UNIVERSIDADE FEDERAL DO RIO DE JANEIROInventors: Marcio Alves Ferreira, Fernanda Pinheiro Da Cruz Waltenberg, Eduardo Romano De Campos Pinto, Maria Fatima Grossi De Sa
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Publication number: 20120272404Abstract: The present invention belongs to an insecticide compound derived from a strain of Bacillus thuringiensis and refers to the field of controlling plant pests, particularly to the control of the boll weevil—Anthonomus grandis. More specifically, the object of the invention refers to a new gene for the new delta-endotoxin designated Cry8Ha and to the cloning and expression of the gene that encodes for the protein Cry8Ha in Escherichia coli. There is provided the nucleotide sequence and encoding protein of the new delta-endotoxin, recombinant vectors and host cells. There is also provided processes and means for recombinant production and the use of the new delta-endotoxin for application in the control of the boll weevil. Additionally, the invention also provides an optimized synthetic gene for expression in cotton plants. Using the gene described herein, it is possible to transform plants based on techniques known by specialists in the art, for the expression of the endotoxin active against the boll weevil.Type: ApplicationFiled: July 26, 2010Publication date: October 25, 2012Applicant: EMBRAPA - Empresa Brasileira de Pesquisa AgropecuariaInventors: Maria Fatima Grossi De Sa, Gustavo Ramos De Oliveira, Maria Cristina Mattar Da Silva, Thales Lima Rocha, Mariana Torquato Quezado De Magalhaes