Patents by Inventor Maria-Fatima Grossi de Sa

Maria-Fatima Grossi de Sa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11525143
    Abstract: Described are methods for promoting increase in plant biomass and yield. This increase has its visible effects in organs such as leaf, stem, root and production of fruits and seeds. Further described is the increase in tolerance of those plants to drought, generating plants better adapted to the environmental changes, improving their growth, biomass and yield.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: December 13, 2022
    Assignee: Universidade Federal Do Rio De Janeiro
    Inventors: Adriana Silva Hemerly, Paulo Cavalcanti Gomes Ferreira, Pan Gong, Hilde Nelissen, Dirk Inzé, Maria Fatima Grossi De Sá, Marcos Fernando Basso, Carolina Vianna Morgante, Maria Eugenia Lisei-De-Sa
  • Publication number: 20210315214
    Abstract: The present invention relates to a process for manufacturing chitosan nanoparticles. The chitosan nanoparticles have dsRNAst adhered onto the surface of the particles. The dsRNAst is selected to have the property to gene silencing of AgraChSII. The invention does also relate to the chitosan nanoparticle, its use in pest-control, as pesticide, and a concentrated suspension containing the chitosan nanoparticles.
    Type: Application
    Filed: July 3, 2018
    Publication date: October 14, 2021
    Applicants: INL - International Iberian Nanotechnology Laboratory, Embrapa
    Inventors: Maria Fátima GROSSI DE SA, Leonardo Lima PEPINO DE MACEDO, Maria Christina Mattar SILVA, Rayssa Almeida GARCIA, Luciano DA SILVA PAULINO, Ana VILA
  • Patent number: 10975386
    Abstract: The present invention relates to the control of pest infestation by inhibiting or reducing the expression of genes of the family of chitin synthase and of vitellogenin, as well as through the expression of the toxin Cry8ka5. The invention further provides method and compositions for controlling pests, by feeding the pest with one or more double-stranded RNA molecules provided by the present invention, as well as double-stranded RNA molecule provided by the present invention, as well as through the action of the toxin Cry8ka5 on the target insect. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules and the toxin protein Cry8ka5. The present invention is preferably used for cotton plants.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: April 13, 2021
    Assignees: EMBRAPA EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA, FUNDAÇÃO UNIVERSIDADE DE BRASÍLIA—FUB—UNB
    Inventors: Maria Fátima Grossi De Sa, Roberta Ramos Coelho, Alexandre Augusto Pereira Fimino, Leonardo Lima Pepino De Macedo, Maria Cristina Mattar Da Silva, Isabela Tristan Lourenço, José Dijair Antonino De Souza Júnior
  • Patent number: 10941387
    Abstract: The present invention relates to the field of insect pests control, using methods and compositions which comprise of alpha-amylase analogous mutant inhibitors (?AIs). More specifically, the invention provides new ?AIs analogous mutant molecules for controlling insect pests, in particular boll weevils (Anthonomus grandis), partially or totally presenting reduction of the amylolytic activity of the digestive enzymes in the intestinal lumen of the insect. Other aspects of the invention include gene constructs containing the nucleic acid molecules that code for the alpha-amylase inhibitors, heterologous expression methods of the new molecules in the active form, and the use of these molecules for controlling insect pests. The invention also provides analogous synthetic genes optimized for their transformation and expression in plants.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: March 9, 2021
    Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA
    Inventors: Maria Fatima Grossi De Sa, Maria Cristina Mattar Da Silva, Rafael Perseguini Del Sarto, Thales Lima Rocha
  • Publication number: 20200347399
    Abstract: Described are methods for promoting increase in plant biomass and yield. This increase has its visible effects in organs such as leaf, stem, root and production of fruits and seeds. Further described is the increase in tolerance of those plants to drought, generating plants better adapted to the environmental changes, improving their growth, biomass and yield.
    Type: Application
    Filed: May 4, 2020
    Publication date: November 5, 2020
    Inventors: Adriana Silva Hemerly, Paulo Cavalcanti Gomes Ferreira, Pan Gong, Hilde Nelissen, Dirk Inzé, Maria Fatima Grossi De Sá, Marcos Fernando Basso, Carolina Vianna Morgante, Maria Eugenia Lisei-De-Sa
  • Patent number: 10822609
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: November 3, 2020
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do Sul
    Inventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
  • Patent number: 10704055
    Abstract: The proposed innovation relates to the biotechnological improvement of plant species of commercial interest. More specifically, the present invention relates to the production of transgenic plants biotechnological with greater tolerance to water deficit and salt stress by means of the expression of a new gene of coffee (of the Coffea Arabica species), belonging to the HD-Zip family, and characterized by a homeodomain associated with a leucine zipper. The expression of this transcriptional factor is induced in leaves and roots of coffee plants subjected to various water deficit conditions (both moderate and severe); transgenic plants that over-express this gene inhibiting greater tolerance both to differ drought intensities and to high salt concentrations.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: July 7, 2020
    Assignees: UNIVERSIDADE FEDERAL DO RIO DE JANEIRO, EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPA
    Inventors: Marcio Alves Ferreira, Fernanda Pinheiro Da Cruz Waltenberg, Eduardo Romano De Campos Pinto, Maria Fatima Grossi De Sa
  • Patent number: 10687529
    Abstract: The present application relates generically to compositions used for controlling agricultural pests and, in a particular, to compositions usable for combating nematodes. The application presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative includes a nematotoxic composition for controlling nematodes that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: June 23, 2020
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA-EMBRAPA, THE UNIVERSITY OF MELBOURNE
    Inventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair Dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
  • Patent number: 10647993
    Abstract: The present invention belongs to an insecticide compound derived from a strain of Bacillus thuringiensis and refers to the field of controlling plant pests, particularly to the control of the boll weevil—Anthonomus grandis. More specifically, the object of the invention refers to a new gene for the new delta-endotoxin designated Cry8Ha and to the cloning and expression of the gene that encodes for the protein Cry8Ha in Escherichia coli. There is provided the nucleotide sequence and encoding protein of the new delta-endotoxin, recombinant vectors and host cells. There is also provided processes and means for recombinant production and the use of the new delta-endotoxin for application in the control of the boll weevil. Additionally, the invention also provides an optimized synthetic gene for expression in cotton plants. Using the gene described herein, it is possible to transform plants based on techniques known by specialists in the art, for the expression of the endotoxin active against the boll weevil.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: May 12, 2020
    Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPA
    Inventors: Maria Fatima Grossi De Sa, Gustavo Ramos De Oliveira, Maria Cristina Mattar Da Silva, Thales Lima Rocha, Mariana Torquato Quezado De Magalhaes
  • Patent number: 10182571
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-stranded RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: January 22, 2019
    Assignee: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA
    Inventors: Maria Fátima Grossi de Sá, Maria Cristina Mattar Da Silva, Leonardo Lima Pepino de Macedo, Alexandre Augusto Pereira Firmino, Roberta Ramos Coelho, Isabela Tristan Lourenço
  • Patent number: 9750247
    Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: September 5, 2017
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA-EMBRAPA, UNITVERSITY OF MELBOURNE
    Inventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
  • Publication number: 20170029843
    Abstract: The present invention relates to the control of pest infestation by inhibiting or reducing the expression of genes of the family of chitin synthase and of vitellogenin, as well as through the expression of the toxin Cry8ka5. The invention further provides method and compositions for controlling pests, by feeding the pest with one or more double-stranded RNA molecules provided by the present invention, as well as double-stranded RNA molecule provided by the present invention, as well as through the action of the toxin Cry8ka5 on the target insect. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules and the toxin protein Cry8ka5. The present invention is preferably used for cotton plants.
    Type: Application
    Filed: December 18, 2014
    Publication date: February 2, 2017
    Applicants: Embrapa - Empresa Brasileira de Pesquisa Agropecuária, Fundação Universidade de Brasília - FUB - UnB
    Inventors: Maria Fátima GROSSI DE SA, Roberta RAMOS COELHO, Alexandre Augusto PEREIRA FIMINO, Leonardo LIMA PEPINO DE MACEDO, Maria Cristina MATTAR DA SILVA, Isabela TRISTAN LOURENÇO
  • Publication number: 20160000086
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-stranded RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-stranded RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Application
    Filed: December 27, 2013
    Publication date: January 7, 2016
    Applicant: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA- EMBRAPA
    Inventors: Maria Fátima Grossi de Sá, Maria Cristina Mattar Da Silva, Leonardo Lima Pepino de Macedo, Alexandre Augusto Pereira Firmino, Roberta Ramos Coelho, Isabela Tristan Lourenço
  • Publication number: 20150368649
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Application
    Filed: December 27, 2013
    Publication date: December 24, 2015
    Applicant: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL
    Inventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
  • Publication number: 20150313220
    Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.
    Type: Application
    Filed: December 26, 2013
    Publication date: November 5, 2015
    Applicants: THE UNIVERSITY OF MELBOURNE, EMPRESA BRASIL EIRA DE PESQUISA AGROPECUARIA- EMBRAPA
    Inventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
  • Publication number: 20150313216
    Abstract: The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically.
    Type: Application
    Filed: December 26, 2013
    Publication date: November 5, 2015
    Applicants: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA- EMBRAPA, THE UNIVERSITY OF MELBOURNE
    Inventors: Thales Lima Rocha, Raphael Garcia de Sousa Evaristo, Maria Fátima Grossi de Sá, Djair Dos Santos de Lima e Souza, Maria Cristina Mattar da Silva, Vera Lúcia Perussi Polez, Ute Roessner, Tony Bacic
  • Patent number: 9012720
    Abstract: A polynucleotide isolated from soybean plants capable of initiating transcription and with sequence identity to SEQ ID No. 1 is provided. In some aspects, the polynucleotide has sequence identity to SEQ ID No. 1 of at least 40%, is the reverse complement or the reverse of such sequences. In some aspects, the polynucleotide is linked to expression enhancers or sequences of interest. In some embodiments, a recombinant vector comprises the polynucleotide. In some aspects, the recombinant vector comprises enhancers, termination sequences, or sequences of interest. In some embodiments a transformed cell, plant, plant part, or propagulum comprise the polynucleotide.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: April 21, 2015
    Assignee: Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi de Sa, Luciane Mourao Guimaraes, Joao Aguiar Nogueira Batista, Antonio Americo Barbosa Viana, Rodrigo da Rocha Fragoso, Maria Cristina Mattar da Silva
  • Publication number: 20140366217
    Abstract: The present invention relates to the field of insect pests control, using methods and compositions which comprise of alpha-amylase analogous mutant inhibitors (?AIs). More specifically, the invention provides new ?AIs analogous mutant molecules for controlling insect pests, in particular boll weevils (Anthonomus grandis), partially or totally presenting reduction of the amylolytic activity of the digestive enzymes in the intestinal lumen of the insect. Other aspects of the invention include gene constructs containing the nucleic acid molecules that code for the alpha-amylase inhibitors, heterologous expression methods of the new molecules in the active form, and the use of these molecules for controlling insect pests. The invention also provides analogous synthetic genes optimized for their transformation and expression in plants.
    Type: Application
    Filed: June 8, 2012
    Publication date: December 11, 2014
    Applicant: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA - EMBRAPA
    Inventors: Maria Fatima Grossi De Sa, Maria Cristina Mattar Da Silva, Rafael Perseguini Del Sarto, Thales Lima Rocha
  • Publication number: 20130340113
    Abstract: The proposed innovation relates to the biotechnological improvement of plant species of commercial interest. More specifically, the present invention relates to the production of transgenic plants biotechnological with greater tolerance to water deficit and salt stress by means of the expression of a new gene of coffee (of the Coffea Arabica species), belonging to the HD-Zip family, and characterized by a homeodomain associated with a leucine zipper. The expression of this transcriptional factor is induced in leaves and roots of coffee plants subjected to various water deficit conditions (both moderate and severe); transgenic plants that over-express this gene inhibiting greater tolerance both to differ drought intensities and to high salt concentrations.
    Type: Application
    Filed: November 8, 2011
    Publication date: December 19, 2013
    Applicant: UNIVERSIDADE FEDERAL DO RIO DE JANEIRO
    Inventors: Marcio Alves Ferreira, Fernanda Pinheiro Da Cruz Waltenberg, Eduardo Romano De Campos Pinto, Maria Fatima Grossi De Sa
  • Publication number: 20120272404
    Abstract: The present invention belongs to an insecticide compound derived from a strain of Bacillus thuringiensis and refers to the field of controlling plant pests, particularly to the control of the boll weevil—Anthonomus grandis. More specifically, the object of the invention refers to a new gene for the new delta-endotoxin designated Cry8Ha and to the cloning and expression of the gene that encodes for the protein Cry8Ha in Escherichia coli. There is provided the nucleotide sequence and encoding protein of the new delta-endotoxin, recombinant vectors and host cells. There is also provided processes and means for recombinant production and the use of the new delta-endotoxin for application in the control of the boll weevil. Additionally, the invention also provides an optimized synthetic gene for expression in cotton plants. Using the gene described herein, it is possible to transform plants based on techniques known by specialists in the art, for the expression of the endotoxin active against the boll weevil.
    Type: Application
    Filed: July 26, 2010
    Publication date: October 25, 2012
    Applicant: EMBRAPA - Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi De Sa, Gustavo Ramos De Oliveira, Maria Cristina Mattar Da Silva, Thales Lima Rocha, Mariana Torquato Quezado De Magalhaes