Patents by Inventor Maria G. Persico

Maria G. Persico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to human cripto protein
    Patent number: 5792616
    Abstract: A new human gene designated as "CRIPTO" gene has been identified and cloned. CRIPTO gene products and derivatives thereof have been obtained and various utilities of the same have been described. Polyclonal and monoclonal antibodies to the human CRIPTO protein have been described. Association of CRIPTO gene with cancers, such as colorectal cancer and breast carcinoma, has been indicated.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 11, 1998
    Assignee: The United States of America
    Inventors: Maria G. Persico, David S. Salomon
  • Cloned human cripto gene and applications thereof
    Patent number: 5654140
    Abstract: A new human gene designated as "CRIPTO" gene has been identified and cloned. CRIPTO gene products and derivatives thereof have been obtained and various utilities of the same have been described. Association of CRIPTO gene with cancers, such as colorectal cancer and breast carcinoma, has been indicated.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: August 5, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Maria G. Persico, David S. Salomon
  • Human cripto-related gene
    Patent number: 5620866
    Abstract: The present invention relates, in general, to a human CRIPTO-related gene. In particular, the present invention relates to a DNA segment encoding a human CRIPTO-related gene; polypeptides encoded by that DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a human CRIPTO-related polypeptide; a DNA segment encoding a genomic clone of the human CRIPTO gene (CR-1); antibodies specific to CR-3; and a method of measuring the amount of CR-3 in a sample.
    Type: Grant
    Filed: November 17, 1993
    Date of Patent: April 15, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David S. Salomon, Maria G. Persico
  • Polypeptide of a human cripto-related gene, CR-3
    Patent number: 5264557
    Abstract: The present invention relates, in general, to a human CRIPTO-related gene. In particular, the present invention relates to a DNA segment encoding a human CRIPTO-related gene; polypeptides encoded by said DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a human CRIPTO-related polypeptide; a DNA segment encoding a genomic clone of the human CRIPTO gene (CR-1); antibodies specific to CR-3; and a method of measuring the amount of CR-3 in a sample.
    Type: Grant
    Filed: August 23, 1991
    Date of Patent: November 23, 1993
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David S. Salomon, Maria G. Persico
  • Human cripto protein
    Patent number: 5256643
    Abstract: A new human gene designated as "CRIPTO" gene has been identified and cloned. CRIPTO gene products and derivatives thereof have been obtained and various utilities of the same have been described. Association of CRIPTO gene with cancers, such as colorectal cancer and breast carcinoma, has been indicated.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: October 26, 1993
    Assignee: The Government of the United States
    Inventors: Maria G. Persico, David S. Salomon