Patents by Inventor Maria Gabriele PSZOLLA

Maria Gabriele PSZOLLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of computational protein design
    Patent number: 10665324
    Abstract: A method for constructing a library of amino-acid sequences having a common structural fold, and a method for designing and selecting an amino-acid sequence having a desired affinity to a molecular surface of interest of a molecular entity, using the library, are provided herein. The methods are based on a stochastic sampling of backbone conformations and amino acid conservation patterns observed in experimentally available protein structures having the common structural fold.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: May 26, 2020
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Sarel Fleishman, Gideon Lapidoth, Maria Gabriele Pszolla, Christoffer Norn
  • METHOD OF COMPUTATIONAL PROTEIN DESIGN
    Publication number: 20170206308
    Abstract: A method for constructing a library of amino-acid sequences having a common structural fold, and a method for designing and selecting an amino-acid sequence having a desired affinity to a molecular surface of interest of a molecular entity, using the library, are provided herein. The methods are based on a stochastic sampling of backbone conformations and amino acid conservation patterns observed in experimentally available protein structures having the common structural fold.
    Type: Application
    Filed: July 6, 2015
    Publication date: July 20, 2017
    Inventors: Sarel FLEISHMAN, Gideon LAPIDOTH, Maria Gabriele PSZOLLA, Christoffer NORN