Patents by Inventor Maria Galanis

Maria Galanis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • V-Like Domain Binding Molecules
    Publication number: 20080305988
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Application
    Filed: May 15, 2008
    Publication date: December 11, 2008
    Inventors: Gregory Coia, Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall
  • V-like domain binding molecules and polynucleotides encoding therefor
    Patent number: 7405288
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: July 29, 2008
    Assignee: Diatech Pty. Ltd.
    Inventors: Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall
  • Method for producing, in yeast, a hydroxylated triple helical protein, and yeast host cells useful in said method
    Publication number: 20080139477
    Abstract: The invention relates to a method for producing hydroxylated triple helical proteins in yeast host cells by introducing to a suitable yeast host cell, DNA sequences encoding the triple helical protein as well as prolyl 4-hydroxylase (PH4), in a manner wherein the introduced DNA sequences are replicated, stably retained and segregated by the yeast host cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 12, 2008
    Inventors: Paul Richard Vaughan, Maria Galanis, John Alan Maurice Ramshaw, Jerome Anthony Werkmeister
  • V-like domain binding molecules
    Publication number: 20070065431
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Application
    Filed: October 27, 2006
    Publication date: March 22, 2007
    Inventors: Gregory Coia, Maria Galanis, Peter Hudson, Robert Irving, Stewart Nuttall
  • V-like domain binding molecules
    Patent number: 7166697
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterized in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: January 23, 2007
    Assignee: Diatech Pty. Ltd.
    Inventors: Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall
  • Method for producing, in yeast, a hydroxylated triple helical protein, and yeast host cells useful in said method
    Publication number: 20030064436
    Abstract: The invention relates to a method for producing hydroxylated triple helical proteins in yeast host cells by introducing to a suitable yeast host cell, DNA sequences encoding the triple helical protein as well as prolyl 4-hydroxylase (PH4), in a manner wherein the introduced DNA sequences are replicated, stably retained and segregated by the yeast host cells.
    Type: Application
    Filed: December 21, 2001
    Publication date: April 3, 2003
    Inventors: Paul Richard Vaughan, Maria Galanis, John Alan Maurice Ramshaw, Jerome Anthony Werkmeister
  • Method for producing, in yeast, a hydroxylated triple helical protein, and yeast host cells useful in said method
    Patent number: 6451557
    Abstract: A method for producing a hydroxylated triple helical protein is disclosed, as well as a yeast host cell used in the method. The method comprises culturing a yeast host cell comprising: (1) a first DNA molecule comprising a DNA sequence encoding P4H&agr; subunit operably linked to a promoter functional in the yeast host cell, (2) a second DNA molecule comprising a DNA sequence encoding P4H&agr; subunit operably linked to a promoter functional in the yeast host cell, and (3) a third DNA molecule comprising a DNA sequence encoding a polypeptide or peptide operably linked to a promoter functional in the yeast host cell, wherein the polypeptide or peptide is one which, when hydroxylated, forms the hydroxylated triple helical protein; and wherein during culturing, each of the first DNA molecule, the second DNA molecule and the third DNA molecule are replicated, stably retained and segregated.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: September 17, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Paul Richard Vaughan, Maria Galanis, John Alan Maurice Ramshaw, Jerome Anthony Werkmeister