Patents by Inventor Maria Giakoumopoulos

Maria Giakoumopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOLATION AND DETECTION OF DNA FROM PLASMA
    Publication number: 20230392189
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: May 1, 2023
    Publication date: December 7, 2023
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • INGESTIBLE SAMPLING DEVICE
    Publication number: 20230190243
    Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 22, 2023
    Inventors: Robert F. Eisele, Michael E. Williams, Prasad G. Iyer, Paul Marrione, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist
  • Isolation and detection of DNA from plasma
    Patent number: 11674168
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: June 13, 2023
    Assignee: Exact Sciences Corporation
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • CHARACTERIZING METHYLATED DNA, RNA, AND PROTEINS IN SUBJECTS SUSPECTED OF HAVING LUNG NEOPLASIA
    Publication number: 20220403471
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 22, 2022
    Inventors: Scott Morris, David Mallery, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, Michael W. Kaiser, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney
  • DETECTING ESOPHAGEAL DISORDERS
    Publication number: 20220349009
    Abstract: Provided herein is technology for screening for esophageal disorders, including but not limited to, Barrett's esophagus (BE). In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of esophageal disorders from a biological sample.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Inventors: William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos
  • CHARACTERIZING METHYLATED DNA, RNA, AND PROTEINS IN THE DETECTION OF LUNG NEOPLASIA
    Publication number: 20220136058
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
    Type: Application
    Filed: November 26, 2019
    Publication date: May 5, 2022
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • DETECTING ENDOMETRIAL CANCER
    Publication number: 20220106644
    Abstract: Provided herein is technology for endometrial cancer (EC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of endometrial cancer and various subtypes of endometrial cancer.
    Type: Application
    Filed: January 24, 2020
    Publication date: April 7, 2022
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Maria Giakoumopoulos
  • SAMPLING DEVICE AND ANALYSIS OF METHYLATED DNA
    Publication number: 20220071605
    Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.
    Type: Application
    Filed: April 16, 2021
    Publication date: March 10, 2022
    Inventors: Robert F. Eisele, Michael E. Williams, Prasad G. Iyer, Paul Marrione, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist
  • DETECTION AND ANALYSIS OF METHYLATED DNA
    Publication number: 20210262042
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Application
    Filed: May 7, 2021
    Publication date: August 26, 2021
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • Detection of neoplasia by analysis of methylated dna
    Patent number: 11028447
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: June 8, 2021
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • ISOLATION AND DETECTION OF DNA FROM PLASMA
    Publication number: 20210079451
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 18, 2021
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • Isolation and detection of DNA from plasma
    Patent number: 10822638
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: November 3, 2020
    Assignee: Exact Sciences Development Company, LLC
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
  • DETECTING HEPATOCELLULAR CARCINOMA
    Publication number: 20200115761
    Abstract: Provided herein is technology for hepatocellular carcinoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of hepatocellular carcinoma.
    Type: Application
    Filed: October 8, 2019
    Publication date: April 16, 2020
    Inventors: William R. Taylor, David A. Ahlquist, Douglas W. Mahoney, John B. Kisiel, Tracy C. Yab, Hatim T. Allawi, Maria Giakoumopoulos, Graham P. Lidgard
  • DETECTION OF LUNG NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20190330702
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Application
    Filed: July 2, 2019
    Publication date: October 31, 2019
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • Detection of lung neoplasia by analysis of methylated DNA
    Patent number: 10385406
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: August 20, 2019
    Assignees: EXACT SCIENCES DEVELOPMENT COMPANY, LLC, Mayo Foundation for Medical Education and Research
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • DETECTING HEPATOCELLULAR CARCINOMA
    Publication number: 20180066320
    Abstract: Provided herein is technology for hepatocellular carcinoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of hepatocellular carcinoma.
    Type: Application
    Filed: September 1, 2017
    Publication date: March 8, 2018
    Inventors: William R. Taylor, David A. Ahlquist, Douglas W. Mahoney, John B. Kisiel, Tracy C. Yab, Hatim T. Allawi, Maria Giakoumopoulos, Graham P. Lidgard
  • DETECTION OF LUNG NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20170335401
    Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
    Type: Application
    Filed: March 28, 2017
    Publication date: November 23, 2017
    Inventors: Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
  • ISOLATION AND DETECTION OF DNA FROM PLASMA
    Publication number: 20170121704
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 4, 2017
    Inventors: Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro