Patents by Inventor Maria Giovanna Luoni

Maria Giovanna Luoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of drospirenone
    Patent number: 9695213
    Abstract: A process is described wherein, by employing 17?-(3-hydroxypropyl)-6?,7?;15?,16?-dimethylene-5?-androstane-3?,5,17?-triol (II) as starting product, in a single stage reaction there is obtained drospirenone, (I), a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic action, that is useful for preparing pharmaceutical compositions with contraceptive action.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: July 4, 2017
    Assignee: INDUSTRIALE CHIMICA S.R.L.
    Inventors: Roberto Lenna, Johannes Bernardus Maria Rewinkel, Francesco Barbieri, Maria Giovanna Luoni
  • Process for the preparation of drospirenone
    Patent number: 9556220
    Abstract: A process is disclosed wherein, using either 17a-(3-hydroxypropyl)-6p,7p;15p,16p-dimethylene-5p-androstane-3p,5,17p-triol (II) or 3?,5^ïI^?^-6?,7?;15?,16?-dimethylene-5?,17?-pregnane-21,17-carbolactone (III) as starting material, through a single-step reaction it is obtained drospirenone (I), a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: January 31, 2017
    Assignee: INDUSTRIALE CHIMICA S.R.L.
    Inventors: Roberto Lenna, Francesco Barbieri, Maria Giovanna Luoni, Monica Noseda
  • PROCESS FOR THE PREPARATION OF DROSPIRENONE
    Publication number: 20160052960
    Abstract: A process is disclosed wherein, using either 17a-(3-hydroxypropyl)-6p,7p;15p,16p-dimethylene-5p-androstane-3p,5,17p-triol (II) or 3?,5?iI???-6?,7?;15?,16?-dimethylene-5?,17?-pregnane-21,17-carbolactone (III) as starting material, through a single-step reaction it is obtained drospirenone (I), a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action.
    Type: Application
    Filed: April 12, 2013
    Publication date: February 25, 2016
    Inventors: Roberto LENNA, Francesco BARBIERI, Maria Giovanna LUONI, Monica NOSEDA
  • Process for the Preparation of Drospirenone
    Publication number: 20160002284
    Abstract: A process is described wherein, by employing 17?-(3-hydroxypropyl) -63,7?3;15?,16?-dimethylene-5?-androstane-3?,5,17?-triol (II) as starting product, in a single stage reaction there is obtained drospirenone, (I), whereby the reaction is achieved using gaseous oxygen as the stoichiometric oxidant in the presence of a catalytic system containing (i) TEMPO or a derivative thereof (ii) a ferric salt (Fe3+) and (iii) NaCl. The product drospirenone is a known synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic action, that is useful for preparing pharmaceutical compositions with contraceptive action.
    Type: Application
    Filed: February 20, 2013
    Publication date: January 7, 2016
    Inventors: Roberto Lenna, Johannes Bernardus Maria Rewinkel, Francesco Barbieri, Maria Giovanna Luoni