Abstract: A method of preparing pancreatic islet-like cell structures having a unique combination of high viability, morphological and functional features that make the pancreatic islet-like cell structures particularly suitable for use in both clinical and drug screening application is provided. Pancreatic islet-like cell structures obtained from the method are also provided.

Abstract: A sterile aqueous pharmaceutical composition contains methylene blue as active ingredient and water, wherein an Azure B impurity content of the composition ranges from 2.0 wt. % to 3.0 wt. %, a pH of the composition is below 4.0, and a total metal content of the pharmaceutical composition is above 20 ppm.

Abstract: A brake device for installation on an axle of wheels including a piston; a casing accommodating at least the piston; a container; a first cast iron disc and a second cast iron disc, joined to the container; a first brake lining; a first supporting disc on which the first brake lining is located; and a bearing fixed to the central cylindrical wall of the container around the axle. The container and the casing remain fixed without rotating about the axle and the first brake lining together with the first supporting disc are fixed to the axle. The piston is further configured to displace the container together with the two cast iron discs towards the first brake lining until the first cast iron disc makes contact with the first brake lining. The container includes an inner circuit configured to accommodate a coolant.

Abstract: An apparatus for studying aerosol includes a test chamber having panels defining an enclosed interior volume. The panels have (i) a first wall having a surface defining an interior of the test chamber, (ii) a second wall defining an exterior of the test chamber, (iii) a void space between the first and second walls, (iv) a panel inlet in communication with the void space, and (v) a panel outlet in communication with the void space. The apparatus includes a chamber inlet port and a chamber outlet port, each extending through one of the panels and in communication with the enclosed interior volume. The apparatus includes a fan disposed in, and positioned and configured to mix air in, the enclosed interior volume. The apparatus includes a trap port extending through one of panels and includes a valve to permit sampling of the contents in the enclosed interior volume.

Abstract: A brake device, configured to be installed directly on a driving axle or through a hub, wherein said device includes a first brake disc joined to the axle sharing rotary motion, a first container disc and a second container disc configured to be moved in the axial direction of said axle. The container discs are positioned on each side of the brake disc, such that both are configured to be moved in the axial direction towards the linings of the first brake disc and to exert a pushing pressure thereon, producing the braking of the brake disc and, therefore, of the driving axle whereon it is assembled. Furthermore, the container discs comprise an inner circuit configured to accommodate the passage of a coolant configured to cool them.

Abstract: The invention relates to a filter for a brake device, comprising a case, a cylindrical tubular filtering element and a dismantlable axial fastening system. The filtering element is located inside the case and the case includes a cylindrical tubular lateral wall having two opposite end edges, a first and a second. The filtering element sits on an internal surface of the lateral wall of the case. The dismantlable axial fastening system provides axial fastening of the filter when same is assembled in the brake device, axial fastening of the filtering element inside the case, and means for assembling and dismantling the filter. The purpose of the filter is to collect all the particles harmful to health that are released each time the brake device brakes, preventing said particles from being transferred to the air that is breathed.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-42’, is provided which forms a spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit black coloration and the fruit nipple is moderately present. The stone of the fruit of the new variety is of very low to low weight, very elongated and possess a moderately rugose surface.

Abstract: The invention relates to a chassis, suitable for use in electric vehicles, characterized in that it comprises: a substantially planar loading bed, suitable for receiving a load on top of same, which is located between at least two front wheels and at least one rear wheel of an electric vehicle; wherein said loading bed comprises a channel the chassis also comprises a central shaft housed in said channel; wherein the loading bed is connected so as to pivot relative to said central shaft; wherein the loading bed comprises a plurality of battery housings distributed symmetrically; and the chassis comprises a rear traction and steering assembly and a front suspension and inclination assembly. The invention likewise relates to an electric vehicle comprising said chassis.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-16’, is provided which forms an upright to spreading growth habit. Fruit with a low weight and obtuse shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of medium weight, moderately elongated and possesses a moderately rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘1-30’, is provided which forms an upright to spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit black coloration and the fruit nipple is moderately present. The stone of the fruit of the new variety is of very low to low weight, very elongated and possess a weak rugose surface.

Abstract: The present invention relates to Christensenellaceae bacteria including Christensenella minuta strain DSM 32891, to the cellular components, metabolites and secreted molecules thereof, and to compositions that comprise the above products, and also to the use of said strain for the prevention and/or treatment of mood or affective disorders, such as depression, stress disorders, anxiety disorders and migraine.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-20’, is provided which forms a dropping growth habit. Fruit with a low weight and obtuse shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of low weight, moderately elongated and possess a weakly rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-31’, is provided which forms a upright to spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of low to medium weight, very elongated and possess a weakly rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-50’, is provided which forms a spreading growth habit. Fruit with a low weight and obtuse shape is produced. The fruit exhibit black coloration and the fruit nipple is either absent or weakly present. The stone of the fruit of the new variety is of very low to low weight, very elongated and possess a weakly rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘1-16’, is provided which forms an upright to spreading growth habit. Fruit with a low weight and obtuse shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of medium weight, moderately elongated and possesses a moderately rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-30’, is provided which forms an upright to spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit black coloration and the fruit nipple is moderately present. The stone of the fruit of the new variety is of very low to low weight, very elongated and possess a weak rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-42’, is provided which forms a spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit black coloration and the fruit nipple is moderately present. The stone of the fruit of the new variety is of very low to low weight, very elongated and possess a moderately rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-31’, is provided which forms a upright to spreading growth habit. Fruit with a low weight and acute shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of low to medium weight, very elongated and possess a weakly rugose surface.

Abstract: A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘I-20’, is provided which forms a dropping growth habit. Fruit with a low weight and obtuse shape is produced. The fruit exhibit dark violet coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of low weight, moderately elongated and possess a weakly rugose surface.