Patents by Inventor Maria Gonzalez Pajuelo

Maria Gonzalez Pajuelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGLOBULIN SINGLE VARIABLE DOMAIN DIRECTED AGAINST HUMAN CXCR4 AND OTHER CELL ASSOCIATED PROTEINS AND METHODS TO GENERATE THEM
    Publication number: 20110117113
    Abstract: The invention relates to immunoglobulin single variable domains directed against specific human CXCR4 epitopes (herein also referred to interchangeably as “compounds of the invention”, “amino acid sequences of the invention”, or “building blocks of the invention”) and polypeptides comprising them (herein also referred to as “polypeptides of the invention”, “compounds of the invention”, or “constructs of the invention”).
    Type: Application
    Filed: October 4, 2010
    Publication date: May 19, 2011
    Inventors: Gerald Beste, Stephanie Staelens, Peter Vanlandschoot, Maria Gonzalez Pajuelo, Hilde Adi Pierrette Revets, Peter Schotte, Hilde Stals, Ann Brige, Maarten Dewilde, Catelijne Stortelers
  • METHOD FOR GENERATION OF IMMUNOGLOBULIN SEQUENCES
    Publication number: 20100173799
    Abstract: The present invention relates to a method for generating immunoglobulin sequences against cell-associated antigens, more particularly, antigens that are membrane-anchored. The invention also provides immunoglobulin sequences obtainable by the method of the invention. Specifically, the present invention relates to the generation of immunoglobulin sequences by use of DNA vaccination. More specifically, the present invention relates to generation of immunoglobulin sequences in camelids, preferably directed against cell-associated antigens, in particular antigens with multiple transmembrane spanning domains, including GPCRs and ion channels, by DNA vaccination. Furthermore, the present invention relates to said immunoglobulin sequences against cell-associated antigens, more particularly, antigens that are membrane-anchored, such as e.g. GPCRs and ion channels, more preferably ion channels.
    Type: Application
    Filed: December 21, 2009
    Publication date: July 8, 2010
    Applicant: Ablynx N.V.
    Inventors: Toon Laeremans, Catelijne Stortelers, Friedrich Nolte, Maria Gonzalez Pajuelo, Joana Assunção, Philippe Van Rompaey