Patents by Inventor Maria Grazia Antonietta Saita

Maria Grazia Antonietta Saita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous ophthalmic formulations based on azithromycin
    Patent number: 10342816
    Abstract: The invention concerns topical ophthalmic preparations in the form of eye-drops in aqueous solution, containing azithromycin (or a pharmacologically acceptable salt thereof) as active ingredient, wherein the azithromycin is solubilized and stabilized by means of ?-cyclodextrins, and in particular by means of the ?-cyclodextrin called sulfobutyl ether ?-cyclodextrin (SBE-?-CD). The proposed preparations have a remarkably high stability, both physical and chemical, which enables its storage at room temperature for the envisaged period of validity for a commercial pharmaceutical product.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: July 9, 2019
    Assignee: MEDIVIS S.R.L.
    Inventors: Danilo Aleo, Maria Grazia Antonietta Saita, Barbara Melilli, Sergio Mangiafico, Melina Cro
  • AQUEOUS OPHTHALMIC FORMULATIONS BASED ON AZITHROMYCIN
    Publication number: 20160074426
    Abstract: The invention concerns topical ophthalmic preparations in the form of eye-drops in aqueous solution, containing azithromycin (or a pharmacologically acceptable salt thereof) as active ingredient, wherein the azithromycin is solubilized and stabilized by means of ?-cyclodextrins, and in particular by means of the ?-cyclodextrin called sulfobutyl ether ?-cyclodextrin (SBE-?-CD). The proposed preparations have a remarkably high stability, both physical and chemical, which enables its storage at room temperature for the envisaged period of validity for a commercial pharmaceutical product.
    Type: Application
    Filed: May 6, 2014
    Publication date: March 17, 2016
    Applicant: MEDIVIS S.R.L.
    Inventors: Danilo ALEO, Maria Grazia Antonietta SAITA, Barbara MELILLI, Sergio MANGIAFICO, Melina CRO
  • Ophthalmic compositions based on polyunsaturated omega-3 and omega-6 fatty acids
    Patent number: 8957110
    Abstract: The invention concerns topical compositions for the prevention and treatment of ocular pathologies, in particular inflammatory keratites and conjunctivites and dry eye syndrome, containing as active ingredients polyunsaturated fatty acids of the types omega-3 and omega-6, and specifically EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and GLA (?-linolenic acid), mixed with vitamin E acetate and formulated in a stable composition in hydrogel, i.e. in dispersed form in an aqueous vehicle containing one or more gelling polymers. The proposed compositions are particularly indicated for use as artificial tears.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: February 17, 2015
    Assignee: TRB Chemedica International S.A.
    Inventors: Danilo Aleo, Stefano Barabino, Sergio Mangiafico, Maurizio Rolando, Maria Grazia Antonietta Saita
  • STABLE OPHTHALMIC FORMULATIONS
    Publication number: 20140163030
    Abstract: Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: February 13, 2014
    Publication date: June 12, 2014
    Applicant: Medivis S.R.L.
    Inventors: Danilo ALEO, Sergio MANGIAFICO, Maria Grazia Antonietta SAITA
  • Stable ophthalmic formulations
    Patent number: 8680078
    Abstract: Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: March 25, 2014
    Assignee: Medivis SRL
    Inventors: Danilo Aleo, Sergio Mangiafico, Maria Grazia Antonietta Saita
  • OPHTHALMIC COMPOSITIONS BASED ON POLYUNSATURATED OMEGA-3 AND OMEGA-6 FATTY ACIDS
    Publication number: 20120010280
    Abstract: The invention concerns topical compositions for the prevention and treatment of ocular pathologies, in particular inflammatory keratites and conjunctivites and dry eye syndrome, containing as active ingredients polyunsaturated fatty acids of the types omega-3 and omega-6, and specifically EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and GLA (?-linolenic acid), mixed with vitamin E acetate and formulated in a stable composition in hydrogel, i.e. in dispersed form in an aqueous vehicle containing one or more gelling polymers. The proposed compositions are particularly indicated for use as artificial tears.
    Type: Application
    Filed: March 18, 2010
    Publication date: January 12, 2012
    Applicant: TRB CHEMEDICA INTERNATIONAL S.A.
    Inventors: Danilo Aleo, Stefano Barabino, Sergio Mangiafico, Maurizio Rolando, Maria Grazia Antonietta Saita
  • STABLE OPHTHALMIC FORMULATIONS
    Publication number: 20110028477
    Abstract: Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: November 7, 2008
    Publication date: February 3, 2011
    Applicant: TECHNOPHARMA SA
    Inventors: Danilo Aleo, Sergio Mangiafico, Maria Grazia Antonietta Saita