Patents by Inventor Maria-Grazia BIFERI

Maria-Grazia BIFERI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTISENSE SEQUENCES FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20230139408
    Abstract: The present invention relates to antisense sequences, nucleic acid constructs and vectors comprising said antisense sequences, and their use for treating a C9orf72 hexanucleotide repeat expansion associated disease such as amyotrophic lateral sclerosis or frontotemporal dementia.
    Type: Application
    Filed: April 9, 2021
    Publication date: May 4, 2023
    Inventors: MARIA-GRAZIA BIFERI, MARISA CAPPELLA, MARTINE BARKATS
  • Treatment of amyotrophic lateral sclerosis
    Patent number: 10590420
    Abstract: The invention relates to a method for the treatment of amyotrophic lateral sclerosis (ALS). Specifically, the invention implements the use of an antisense sequence adapted to affect alternative splicing in a human SOD1 pre-mRNA, thereby leading to the destruction of the skipped m RNA by the cell machinery.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: March 17, 2020
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Martine Barkats, Maria-Grazia Biferi, Thomas Voit
  • TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20170152517
    Abstract: The invention relates to a method for the treatment of amyotrophic lateral sclerosis (ALS). Specifically, the invention implements the use of an antisense sequence adapted to affect alternative splicing in a human SOD1 pre-mRNA, thereby leading to the destruction of the skipped m RNA by the cell machinery.
    Type: Application
    Filed: July 31, 2015
    Publication date: June 1, 2017
    Inventors: Martine BARKATS, Maria-Grazia BIFERI, Thomas VOIT