Patents by Inventor Maria Grazia De Simoni

Maria Grazia De Simoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 9211318
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: December 15, 2015
    Assignee: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Kallikrein-inhibitor therapies
    Patent number: 9114144
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: August 25, 2015
    Assignee: Dyax Corp.
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Use Of C1 Inhibitor For The Prevention Of Ischemia-Reperfusion Injury
    Publication number: 20130244941
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: February 25, 2013
    Publication date: September 19, 2013
    Applicant: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 8415288
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: April 9, 2013
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • USE OF C1 INHIBITOR FOR THE PREVENTION OF ISCHEMIA-REPERFUSION INJURY
    Publication number: 20120088728
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: October 11, 2011
    Publication date: April 12, 2012
    Applicant: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • KALLIKREIN-INHIBITOR THERAPIES
    Publication number: 20120015881
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Application
    Filed: September 8, 2011
    Publication date: January 19, 2012
    Applicant: DYAX CORP.
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 8071532
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 6, 2011
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • KALLIKREIN-INHIBITOR THERAPIES
    Publication number: 20090117130
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 7, 2009
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Kallikrein-Inhibitor Therapies
    Publication number: 20090062195
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Application
    Filed: October 30, 2007
    Publication date: March 5, 2009
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Use of C1 Inhibitor for the Prevention of Ischemia-Reperfusion Injury
    Publication number: 20080305993
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 11, 2008
    Applicant: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Kallikrein-Inhibitor Therapies
    Publication number: 20080226655
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 18, 2008
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Kallikrein-Inhibitor Therapies
    Publication number: 20080139473
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 12, 2008
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini
  • Kallikrein-inhibitor therapies
    Patent number: 7153829
    Abstract: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 26, 2006
    Assignee: Dyax Corp.
    Inventors: Robert C. Ladner, Arthur C. Ley, Shirish Hirani, Anthony Williams, Maria Grazia De Simoni, Luigi Bergamaschini