Patents by Inventor Maria Halasz

Maria Halasz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Midkine antibody
    Patent number: 10590192
    Abstract: The present disclosure is directed to isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (MK) and their use as therapeutic and/or diagnostic agents for midkine-related disorders. The present disclosure is also related to nucleic acid sequences which encode said proteins and their expression in recombinant host cells. In particular, the present disclosure is directed towards humanized antibodies derived from murine antibody IP14 which specifically bind to human MK.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: March 17, 2020
    Assignee: CELLMID LIMITED
    Inventors: Maria Halasz, Darren Jones, Nico Mertens, Phillip Cunnah
  • Methods of treating bone diseases, disorders and/or injuries and reagents therefor
    Publication number: 20190092848
    Abstract: The present disclosure relates to methods and reagents for treating bone disorders and/or increasing bone healing. In particular, present disclosure relates to the use of isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (hereinafter, referred to as “MK”) in the treatment of bone disorders and/or to increase bone healing.
    Type: Application
    Filed: March 1, 2017
    Publication date: March 28, 2019
    Inventors: Darren Jones, Maria Halasz, Astrid Liedert, Melanie Haffner-Luntzer, Anita Ignatius
  • Method of Treatment of Alopecia with Monoterpenoids
    Publication number: 20180360792
    Abstract: The present application generally relates to topical formulations comprising monoterpenoid compounds which are effective inhibitors of FGF-5-dependent signaling in hair follicles or parts thereof, the manufacture of such topical formulations, and their use to reduce, delay or prevent loss of terminal hair caused by FGF-5 signaling in the hair follicle, such as in subjects suffering from, or having a propensity to develop, alopecia.
    Type: Application
    Filed: July 19, 2018
    Publication date: December 20, 2018
    Inventors: Masakuni Yamamoto, Masato Namekata, Koichi Yamauchi, Takeo Matsumoto, Darren Ross Jones, Maria Halasz
  • Improved midkine antibody
    Publication number: 20170240628
    Abstract: The present disclosure is directed to isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (MK) and their use as therapeutic and/or diagnostic agents for midkine-related disorders. The present disclosure is also related to nucleic acid sequences which encode said proteins and their expression in recombinant host cells. In particular, the present disclosure is directed towards humanized antibodies derived from murine antibody IP14 which specifically bind to human MK.
    Type: Application
    Filed: October 14, 2015
    Publication date: August 24, 2017
    Inventors: Maria Halasz, Darren Jones, Nico Martens, Phillip Cunnah
  • Antibody recognizing N-domain of midkine
    Patent number: 9624294
    Abstract: The present disclosure relates to isolated or recombinant proteins, such as antibodies, which inhibit or reduce the function of midkine (hereinafter, referred to as “MK”) for use in the treatment or prevention of midkine-related disorders.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: April 18, 2017
    Assignee: Cellmid Limited
    Inventors: Sadatosi Sakuma, Maria Halasz, Darren Jones
  • Method of treatment or prevention of hair loss or for the enhancement of hair growth
    Patent number: 9622955
    Abstract: The present application relates to use of a Midkine family protein for growing hair on a mammal, or in the manufacture of a medicament for growing hair on a mammal, especially for treatment or prevention of different forms of alopecia.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: April 18, 2017
    Assignee: Advangen International Pty Ltd
    Inventors: Sadatoshi Sakuma, Maria Halasz, Darren Jones
  • Method of Treatment of Alopecia with Monoterpenoids
    Publication number: 20160374979
    Abstract: The present application generally relates to topical formulations comprising monoterpenoid compounds which are effective inhibitors of FGF-5-dependent signalling in hair follicles or parts thereof, the manufacture of such topical formulations, and their use to reduce, delay or prevent loss of terminal hair caused by FGF-5 signalling in the hair follicle, such as in subjects suffering from, or having a propensity to develop, alopecia
    Type: Application
    Filed: December 12, 2014
    Publication date: December 29, 2016
    Inventors: Masakuni Yamamoto, Masato Namekata, Koichi Yamauchi, Takeo Matsumoto, Darren Ross Jones, Maria Halasz
  • Method of Treatment or Prevention of Hair Loss or for the Enhancement of Hair Growth
    Publication number: 20150044139
    Abstract: The present application relates to use of a Midkine family protein for growing hair on a mammal, or in the manufacture of a medicament for growing hair on a mammal, especially for treatment or prevention of different forms of alopecia.
    Type: Application
    Filed: August 20, 2014
    Publication date: February 12, 2015
    Inventors: Sadatoshi Sakuma, Maria Halasz, Darren Jones
  • ANTIBODY RECOGNIZING N-DOMAIN OF MIDKINE
    Publication number: 20140170144
    Abstract: The present disclosure relates to isolated or recombinant proteins, such as antibodies, which inhibit or reduce the function of midkine (hereinafter, referred to as “MK”) for use in the treatment or prevention of midkine-related disorders.
    Type: Application
    Filed: March 13, 2012
    Publication date: June 19, 2014
    Applicant: Cellmid Limited
    Inventors: Sadatosi Sakuma, Maria Halasz, Darren Jones
  • Method of Treatment or Prevention of Hair Loss or for the Enhancement of Hair Growth
    Publication number: 20130067604
    Abstract: The present application relates to use of a Midkine family protein for growing hair on a mammal, or in the manufacture of a medicament for growing hair on a mammal, especially for treatment or prevention of different forms of alopecia.
    Type: Application
    Filed: February 23, 2011
    Publication date: March 14, 2013
    Inventors: Sadatoshi Sakuma, Maria Halasz, Darren Jones