Patents by Inventor Maria Jesus Martin

Maria Jesus Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20220098289
    Abstract: The invention provides a therapeutic target for the screening of drugs for the treatment of Alzheimer's disease (AD), as well as neutralizing monoclonal antibodies against said target and their use for the treatment of AD. The invention also refers to a kit comprising the antibodies and to an in vitro method for the diagnosis of AD in which preferably the antibodies or the kit comprising them are used.
    Type: Application
    Filed: February 17, 2020
    Publication date: March 31, 2022
    Inventors: Javier RUEDA CARRASCO, María Inés MATEO RUIZ, María Jesús MARTIN BERMEJO, María Pilar ESTEVE PASTOR, Paola BOVOLENTA NICOLAO, Inmaculada MORENO IRUELA, Mercedes DOMÍNGUEZ RODRÍGUEZ
  • ANTICANCER COMPOUNDS
    Publication number: 20220056021
    Abstract: Anticancer compounds of formula (I) and derivatives thereof are provided.
    Type: Application
    Filed: December 17, 2019
    Publication date: February 24, 2022
    Inventors: María Jesús Martín López, Raquel Rodríguez Acebes, Patricia Gema Cruz López, Andrés M. Francesch Solloso, Maria del Carmen Cuevas Marchante
  • USE OF SPECIFIC CARBOHYDRATE SYSTEMS DURING PREGNANCY FOR IMPROVING BONE DEVELOPMENT AND FORMATION AND/OR FOR IMPROVING COGNITIVE AND CNS DEVELOPMENT IN OFFSPRING
    Publication number: 20160030466
    Abstract: The present disclosure is directed to the administration of specific carbohydrate systems to a pregnant and/or lactating woman for improving one or more characteristics in offspring, for example cognition and/or bone health. The carbohydrate system may include a slow rate of digestion simple carbohydrate, a complex carbohydrate, and a non-absorbent carbohydrate and/or an indigestible carbohydrate.
    Type: Application
    Filed: March 12, 2014
    Publication date: February 4, 2016
    Applicant: ABBOTT LABORATORIES
    Inventors: José María López Pedrosa, Manuel Cristóbal Manzano Martín, María-Jesús Martín Martín, Elena Oliveros Delgado, Ricardo Rueda Cabrera, María del Pilar Bueno Vargas
  • EARLY PROGRAMMING OF BRAIN FUNCTION THROUGH SOY PROTEIN FEEDING
    Publication number: 20120270766
    Abstract: Disclosed are methods for improving memory and/or cognition in an infant by administering soy protein to the infant's mother during pregnancy, and further administering soy protein to the infant after delivery. The soy protein may be administered to the infant's mother during lactation if the infant is breastfed and/or may be directly administered, for example, by administering the infant an infant and/or nutritional formula comprising soy protein. Also disclosed are compositions comprising soy protein that may be used in the methods.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 25, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Ricardo Rueda Cabrera, Alejandro Barranco Perez, Maria Ramirez Gonzalez, Maria Jesus Martin
  • Antitumoral analogs of ET-743
    Patent number: 8012975
    Abstract: Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: September 6, 2011
    Assignee: Pharma Mar, S.A.
    Inventors: Ignacio Manzanares, Carmen Cuevas, Marta Perez, Maria Jesus Martin, Alberto Rodriguez, Simon Munt
  • Antitumoral Tetrahydro-Pyrimidines
    Publication number: 20100216817
    Abstract: Antitumoral compounds of the formula (I) wherein X is O, S, or NRa, obtained from a maze coral of the family Meandrinidae, genus Meandrina, species meandrites, or derivatives thereof are useful as antitumoral agents.
    Type: Application
    Filed: May 3, 2006
    Publication date: August 26, 2010
    Applicant: Pharma Mar SA
    Inventors: José Fernando Reyes Benitez, Maria del Carmen Cuevas Marchante, David Montalvo Lobo, Maria-Jesús Martin López, Maria Cristina Mateo Urbano, Andrés Francesch Solloso
  • Antitumoral analogs of ET-743
    Patent number: 7410969
    Abstract: Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: August 12, 2008
    Assignee: Pharma Mar, S.A.
    Inventors: Ignacio Manzanares, María Jesús Martin, Alberto Rodriguez, Simon Munt, Carmen Cuevas, Marta Perez
  • Antitumoral analogs of et-743
    Patent number: 7247629
    Abstract: Antitumour compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: July 24, 2007
    Assignee: Pharma Mar, S.A.
    Inventors: Ignacio Manzanares, María Jesús Martin, Alberto Rodriguez, Simon Munt, Carmen Cuevas, Marta Perez
  • Anititumoral analogs of et-743
    Publication number: 20040019056
    Abstract: Antitumour compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.
    Type: Application
    Filed: March 31, 2003
    Publication date: January 29, 2004
    Inventors: Ignacio Manzanares, Maria Jesus Martin, Alberto Rodriguez, Simon Munt, Carmen Cuevas, Marta Perez
  • Synthetic process for the manufacture of an ecteinaschidin compound
    Publication number: 20040002602
    Abstract: Processes are provided for preparing compounds with a fused ring structure of formula (XIV). Such products include ecteinascidins and have a spiroamine-1,4-bridge. The process involving forming a 1,4 bridge using a 1-labile, 10-hydroxy, 18-protected hydroxy, di-6,8-en-5-one fused ring compound. After formation of the 1,4 bridge, C-18 protection is removed before spiroamine introduction.
    Type: Application
    Filed: March 31, 2003
    Publication date: January 1, 2004
    Inventors: Andres Francesch, Carolina Fernandez, Jose Luis Chicharro, Pilar Gallego, Maria Zarzuelo, Ignacio Manzanares, Marta Perez, Carmen Cuevas, Maria Jesus Martin, Simon Munt
  • Antitumour 1,5-diazaanthraquinones
    Patent number: 6525063
    Abstract: Compounds having formula (I) wherein R3, R4, R7 and R8 are independently selected from the group consisting of hydrogen, lower alkyl, halogen, amine, mono(lower)alkylamine, di(lower)alkylamine, phenyl, or substituted phenyl possess antitumor activity and are new with the exception of the compound in which R3, R4, R7, R8 are all hydrogen and the compound in which R3 and R7 are hydrogen, R4 is chlorine, and R8 is a 2-nitrophenyl group.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: February 25, 2003
    Assignee: Universidad Complutense de Madrid
    Inventors: Carmen Avendano, José María Perez, Maria del Mar Blanco, José Carlos Menendez, Dolores Garcia Gravalos, Jesús Angel de la Fuente, María Jesús Martin
  • Antitumour 1,5-diazaanthraquinones
    Publication number: 20020099066
    Abstract: 1 Compounds having formula (I) wherein R3, R4, R7, and R8 are independently selected from the group consisting of hydrogen, lower alkyl, halogen, amine, mono(lower)alkylamine, di(lower)alkylamine, phenyl, or substituted phenyl possess antitumor activity and are new with the exception of the compound in which R3, R4, R7, R8 are all hydrogen and the compound in which R3 and R7 are hydrogen, R4 chlorine, and R8 is a 2-nitrophenyl group.
    Type: Application
    Filed: July 11, 2001
    Publication date: July 25, 2002
    Inventors: Carmen Avendano, Jose Maria Perez, Maria del Mar Blanco, Jose Carlos Menendez, Dolores Garcia Gravalos, Jesus Angel de la Fuente, Maria Jesus Martin