Patents by Inventor Maria Jose Verde-Casanova

Maria Jose Verde-Casanova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclopropyl derivatives, preparation method there-of and applications
    Patent number: 5834490
    Abstract: Cyclopropyl derivatives of formula (I) wherein R is cyclopropyl or methyllopropyl are prepared by reaction of 2,6-dibromohexanoyl chloride with 2,6-dimethylaniline in the presence of a base at 0.degree.-25.degree. C. to give 2,6-dibromohexanoyl-2,6-dimethylanilide which subsequently is reacted with R--NH.sub.2 (wherein R is cyclopropyl or methylcyclopropyl) at 70.degree.-100.degree. C. The compounds are useful as antiarrhythmic agents and as local anaesthetic agents.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 10, 1998
    Assignee: Instituto de Investigacion y Desarrolo Quimico Biologico, S.A.
    Inventors: Maria Jose Verde-Casanova, Alvaro Galiano-Ramos