Patents by Inventor Maria Kazimirova

Maria Kazimirova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombin inhibitors
    Patent number: 10906946
    Abstract: The present invention provides isolated peptides, variants and fragments thereof that are capable of binding with a high level of specificity to thrombin and inhibiting its activity. There is also provided uses of such peptides in methods of diagnosis and treatment, coating of medical devices and nucleic acids encoding the same.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: February 2, 2021
    Assignees: National University of Singapore, Institute of Zoology, Slovak Academy of Sciences
    Inventors: Janaki Krishnamoorthy Iyer, Cho Yeow Koh, R. Manjunatha Kini, Maria Kazimirova, Ladislav Roller
  • NOVEL THROMBIN INHIBITORS
    Publication number: 20190002511
    Abstract: The present invention provides isolated peptides, variants and fragments thereof that are capable of binding with a high level of specificity to thrombin and inhibiting its activity. There is also provided uses of such peptides in methods of diagnosis and treatment, coating of medical devices and nucleic acids encoding the same.
    Type: Application
    Filed: June 17, 2016
    Publication date: January 3, 2019
    Applicants: National University of Singapore, Institute of Zoology, Slovak Academy of Sciences
    Inventors: Janaki Krishnamoorthy IYER, Cho Yeow KOH, R. Manjunatha KINI, Maria KAZIMIROVA, Ladislav ROLLER
  • THROMBIN INHIBITOR
    Publication number: 20130183237
    Abstract: The invention relates to thrombin inhibitors derived from the salivary glands of haematophagous arthropods and in particular to bivalent and trivalent thrombin inhibitors that act by interacting with thrombin at two or three different sites.
    Type: Application
    Filed: June 18, 2008
    Publication date: July 18, 2013
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Maria Kazimirova, R. Manjunatha Kini, Cho Yeow Koh
  • Vaccine against infectious disease
    Publication number: 20050123556
    Abstract: The present invention relates to the use of a protein termed 64p in the production of vaccines for protecting animals against the bite of blood-sucking ectoparasites and against the transmission of viruses, bacteria and other pathogens by such ectoparasites.
    Type: Application
    Filed: October 7, 2002
    Publication date: June 9, 2005
    Inventors: Patrica Nuttall, Adama Trimnell, Milan Labuda, Maria Kazimirova, Martinus Lickova
  • Ion channel modulators
    Publication number: 20050090437
    Abstract: The present invention relates to ion channel modulators. In particular, the invention relates to ion channel modulators that are derived from haematophagous arthropods. The invention also relates to the use of ion channel modulators from haematophagous arthropods in the treatment and prevention of certain diseases and conditions in mammals, including humans.
    Type: Application
    Filed: December 22, 2003
    Publication date: April 28, 2005
    Inventors: Patricia Nuttall, Miles Nunn, Peter Takac, Olga Pechanova, Petra Rajska, Milan Kozanek, Norbert Vrbjar, Maria Kazimirova, Milan Labuda