Patents by Inventor Maria Koehler

Maria Koehler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230165966
    Abstract: The present invention relates to a method of treating cancer in a subject.
    Type: Application
    Filed: July 11, 2022
    Publication date: June 1, 2023
    Inventors: Maria KOEHLER, Gillian Langford, Stefan Symeonides
  • Publication number: 20210177856
    Abstract: Disclosed are methods of treating a cancer in a subject using an ATR inhibitor and PARP inhibitor. wherein the cancer has been previously identified as a cancer having a loss of function of ATM, BRCA2, RNAse H2A, RNAse H2B, CDK12, or a combination thereof, or as an ALT+ cancer. Also disclosed are methods of inducing cell death in an aberrant cancer cell having a loss of function of ATM, BRCA2, RNAse H2A, RNAse H2B, CDK12, or a combination thereof, or an ALT+ cancer cell, by contacting the cell with an effective amount of an ATR inhibitor and PARP inhibitor.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 17, 2021
    Inventors: Michal ZIMMERMANN, Anne ROULSTON, Maria KOEHLER
  • Publication number: 20200129630
    Abstract: The present invention relates to a method of treating cancer in a subject.
    Type: Application
    Filed: October 30, 2019
    Publication date: April 30, 2020
    Inventors: Maria Koehler, Gillian Langford, Stefan Symeonides