Patents by Inventor Maria Koufaki

Maria Koufaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiprotozoal ring-substituted phospholipids
    Patent number: 8097752
    Abstract: Disclosed are novel ring containing phospholipids represented by the structural formula A-X—PO3—W and physiologically acceptable salts thereof and a process for the preparation of these compounds. The compounds can be used for the treatment of protozoal diseases and especially leishmaniasis.
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: January 17, 2012
    Assignee: MAKScientific, LLC
    Inventors: Theodora Calogeropoulou, Maria Koufaki, Nikolaos Avlonitis, Alexandros Makriyannis
  • Bifunctional agents possessing antioxidant and antiarrhythmic activity
    Patent number: 7115657
    Abstract: The present invention relates to novel bifunctional agents possessing antioxidant and antiarrhytmic activity, methods for the synthesis of the same and their applications in treating ischemia-reperfusion injury, as well as a variety of disorders related to free radicals and/or arrhythmias. These bifunctional drugs should preferentially segregate in the membrane and produce their antiarrhytmic effects while, at the same time, help in protecting the membrane lipids by scavenging free radicals.
    Type: Grant
    Filed: July 4, 2001
    Date of Patent: October 3, 2006
    Assignee: Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
    Inventors: Maria Koufaki, Theodora Calogeropoulou, Alexandros Makriyannis
  • Antiprotozoal ring-substiuted phospholipids
    Publication number: 20060105998
    Abstract: Disclosed are novel ring containing phospholipids represented by the structural formula A-X—PO3—W and physiologically acceptable salts thereof and a process for the preparation of these compounds. The compounds can be used for the treatment of protozoal diseases and especially leishmaniasis.
    Type: Application
    Filed: October 29, 2003
    Publication date: May 18, 2006
    Applicant: MAK Scientific Corporation
    Inventors: Theodora Calogeropoulou, Maria Koufaki, Nikolaos Avlonitis, Alexandros Makriyannis
  • Bifunctional agents possessing antioxidant and antiarrhythmic activity
    Publication number: 20040259763
    Abstract: The present invention relates to novel bifunctional agents possessing antioxidant and antiarrhytmic activity, methods for the synthesis of the same and their applications in treating ischemia-reperfusion injury, as well as a variety of disorders related to free radicals and/or arrhythmias. These bifunctional drugs should prefrentially segregate in the membrane and produce their antiarrhytmic effects while, at the same time, help in protecting the membrane lipids by scavenging free radicals. The present invention comprises compounds represented by Formula (I), wherein R1, R2, R3, R4, R5 are further defined.
    Type: Application
    Filed: January 9, 2003
    Publication date: December 23, 2004
    Inventors: Maria Koufaki, Theodora Calogeropoulou, Alexandros Makriyannis