Patents by Inventor Maria-Laura SARGENTINI

Maria-Laura SARGENTINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11149089
    Abstract: Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: October 19, 2021
    Assignee: Ablynx N.V.
    Inventors: Josefin-Beate Holz, Stefaan Rossenu, Steven De Bruyn, Maria-Laura Sargentini-Maier, Özkan Yalkinoglu
  • Patent number: 11008393
    Abstract: Methods are provided for the treatment of IL-6R related diseases. More specifically, specific dose regimens and pre-filled syringes are provided for subcutaneous administration, to subjects suffering an IL-6R related disease, of immunoglobulin single variable domains that bind IL-6R.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: May 18, 2021
    Assignee: Ablynx N.V.
    Inventors: Sven Hoefman, Maria-Laura Sargentini-Maier, Katrien Van Beneden
  • Patent number: 10561805
    Abstract: Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of hRSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: February 18, 2020
    Assignees: ABLYNX N.V., VECTURA GMBH
    Inventors: Koen Allosery, Erik Depla, Martin Huber, Tobias Kolb, Bernhard Müllinger, Massimiliano Germani, Juliane Schick, Maria-Laura Sargentini
  • Publication number: 20190127447
    Abstract: Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of h RSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.
    Type: Application
    Filed: May 2, 2017
    Publication date: May 2, 2019
    Applicant: Ablynx N.V.
    Inventors: Maria-Laura Sargentini-Maier, Koen Allosery, Erik Depla, Massimiliano Germani
  • Publication number: 20190119393
    Abstract: Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
    Type: Application
    Filed: October 2, 2018
    Publication date: April 25, 2019
    Applicant: Ablynx N.V.
    Inventors: Josefin-Beate Holz, Stefaan Rossenu, Steven De Bruyn, Maria-Laura Sargentini-Maier, Özkan Yalkinoglu
  • Publication number: 20190119392
    Abstract: Methods are provided for the treatment of IL-6R related diseases. More specifically, specific dose regimens and pre-filled syringes are provided for subcutaneous administration, to subjects suffering an IL-6R related disease, of immunoglobulin single variable domains that bind IL-6R.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 25, 2019
    Applicant: Ablynx N.V.
    Inventors: Sven Hoefman, Maria-Laura Sargentini-Maier, Katrien Van Beneden
  • Patent number: 10138302
    Abstract: Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: November 27, 2018
    Assignee: Ablynx N.V.
    Inventors: Josefin-Beate Holz, Stefaan Rossenu, Steven De Bruyn, Maria Laura Sargentini-Maier, Özkan Yalkinoglu
  • Patent number: 10118967
    Abstract: Methods are provided for the treatment of IL-6R related diseases. More specifically, specific dose regimens and pre-filled syringes are provided for subcutaneous administration, to subjects suffering an IL-6R related disease, of immunoglobulin single variable domains that bind IL-6R.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: November 6, 2018
    Assignee: Ablynx N.V.
    Inventors: Sven Hoefman, Maria Laura Sargentini-Maier, Katrien Van Beneden
  • Publication number: 20170304566
    Abstract: Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of hRSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 26, 2017
    Inventors: Koen ALLOSERY, Erik DEPLA, Martin HUBER, Tobias KOLB, Bernhard MÜLLINGER, Massimiliano GERMANI, Juliane SCHICK, Maria-Laura SARGENTINI
  • Publication number: 20160326252
    Abstract: Methods are provided for the treatment of IL-6R related diseases. More specifically, specific dose regimens and pre-filled syringes are provided for subcutaneous administration, to subjects suffering an IL-6R related disease, of immunoglobulin single variable domains that bind IL-6R.
    Type: Application
    Filed: October 21, 2015
    Publication date: November 10, 2016
    Applicant: ABLYNX NV
    Inventors: Sven Hoefman, Maria Laura Sargentini-Maier, Katrien Van Beneden
  • Publication number: 20150050268
    Abstract: Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
    Type: Application
    Filed: September 24, 2012
    Publication date: February 19, 2015
    Inventors: Josefin-Beate Holz, Stefaan Rossenu, Steven De Bruyn, Maria Laura Sargentini-Maier, Ozkan Yalkinoglu
  • Publication number: 20140212417
    Abstract: Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
    Type: Application
    Filed: September 24, 2012
    Publication date: July 31, 2014
    Applicant: Ablynx N.V.
    Inventors: Josefin-Beate Holz, Stefaan Rossenu, Steven De Bruyn, Maria Laura Sargentini-Maier, Özkan Yalkinoglu