Patents by Inventor Maria Lia Palomba

Maria Lia Palomba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and compositions for stimulation of an immune response to CD20 using a xenogeneic CD20 antigen
    Patent number: 8021666
    Abstract: Tolerance of the immune system for endogenous CD20 can be overcome and an immune response stimulated by administration of xenogeneic or xenoexpressed CD20 antigen. For example, mouse CD20, or antigenically-effective portions thereof, can be used to stimulate an immune response to the corresponding differentiation antigen in a human subject. Administration of xenogeneic antigens in accordance with the invention results in an effective immunity against CD20 expressed by the cancer in the treated individual, thus providing a therapeutic approach to the treatment of lymphomas and leukemia expressing CD20.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: September 20, 2011
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Maria Lia Palomba, Alan Houghton, Jedd Wolchok, David A. Scheinberg, Wendy K. Roberts
  • Method and compositions for stimulation of an immune response to CD20 using a xenogeneic CD20 antigen
    Publication number: 20030228326
    Abstract: Tolerance of the immune system for endogenous CD20 can be overcome and an immune response stimulated by administration of xenogeneic or xenoexpressed CD20 antigen. For example, mouse CD20, or antigenically-effective portions thereof, can be used to stimulate an immune response to the corresponding differentiation antigen in a human subject. Administration of xenogeneic antigens in accordance with the invention results in an effective immunity against CD20 expressed by the cancer in the treated individual, thus providing a therapeutic approach to the treatment of lymphomas and leukemia expressing CD20.
    Type: Application
    Filed: October 31, 2002
    Publication date: December 11, 2003
    Inventors: Maria Lia Palomba, Alan Houghton, Jedd Wolchok, David A. Scheinberg, Wendy K. Roberts