Patents by Inventor Maria Luisa Nolli

Maria Luisa Nolli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Idiotypic vaccine
    Patent number: 8512703
    Abstract: The invention concerns the use of recombinant clonotypic immunoglobulins (Ig) as a vaccine in the treatment of HCV-related and non HCV-related lymphoproliferations, in particular the use of recombinant proteins with immunogenic properties derived from protein segments VK3-20 and VK3-15 of Ig light chains derived from patients with lymphoproliferations.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: August 20, 2013
    Assignee: Areta International S.R.L.
    Inventors: Riccardo Dolcetti, Massimo Guidoboni, Valli De Re, Daniela Gasparotto, Sonia Castiglioni, Maria Luisa Nolli
  • Anti-HMGA1 monoclonal antibodies, process for their preparation and their use for the quantitative determination of HMGA1
    Patent number: 8394931
    Abstract: This invention concerns a panel of monoclonal antibodies against the High Mobility Group A 1 protein (HMGA1) and a process for preparing them, as well as the use of said antibodies for the quantitative determination of HMGA1 in biological fluids or in protein Iy sates deriving from lymphocyte cells. This invention also concerns a diagnostic kit for assessing risk factors related to the expression of the HMGA1 proteins.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: March 12, 2013
    Assignee: Areta International S.R.L.
    Inventors: Alfredo Fusco, Antonio Orlandi, Maria Luisa Nolli
  • ANTI-HMGA1 MONOCLONAL ANTIBODIES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE QUANTITATIVE DETERMINATION OF HMGA1
    Publication number: 20110123557
    Abstract: This invention concerns a panel of monoclonal antibodies against the High Mobility Group A 1 protein (HMGA1) and a process for preparing them, as well as the use of said antibodies for the quantitative determination of HMGA1 in biological fluids or in protein Iy sates deriving from lymphocyte cells. This invention also concerns a diagnostic kit for assessing risk factors related to the expression of the HMGA1 proteins.
    Type: Application
    Filed: April 29, 2009
    Publication date: May 26, 2011
    Inventors: Alfredo Fusco, Antonio Orlandi, Maria Luisa Nolli
  • IDIOTYPIC VACCINE
    Publication number: 20100310586
    Abstract: The invention concerns the use of recombinant clonotypic immunoglobulins (Ig) as a vaccine in the treatment of HCV-related and non HCV-related lymphoproliferations, in particular the use of recombinant proteins with immunogenic properties derived from protein segments VK3-20 and VK3-15 of Ig light chains derived from patients with lymphoproliferations.
    Type: Application
    Filed: July 24, 2008
    Publication date: December 9, 2010
    Applicant: ARETA INTERNATIONAL S.r.l
    Inventors: Riccardo Dolcetti, Massimo Guidoboni, Valli De Re, Daniela Gasparotto, Sonia Castiglioni, Maria Luisa Nolli
  • Procedure for the large-scale T-lymphocytes culture in a homogeneous system
    Patent number: 7678571
    Abstract: The present invention refers to a procedure for the large-scale amplification of human lymphocytic cell lines for therapeutic use, consisting of a homogeneous culture system. The claimed invention also refers to the production of therapeutic doses of lymphocytic cells cultured homogeneously.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: March 16, 2010
    Assignee: Abiogen Pharma S.p.A.
    Inventors: Silvia Trasciatti, Maria Luisa Nolli, Luigi Cavenaghi, Nadia De Bernardi