Patents by Inventor Maria Luz Martinez Chantar

Maria Luz Martinez Chantar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL
    Publication number: 20230265438
    Abstract: The invention relates to nucleic acid products that interfere with or inhibit CNNM4 (Cyclin M4) gene expression. It further relates to therapeutic uses of CNNM4 inhibition for the treatment of diseases, such as liver diseases including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), liver steatosis, liver fibrosis, liver cirrhosis, liver cancer and other diseases associated with magnesium dysregulation.
    Type: Application
    Filed: May 26, 2021
    Publication date: August 24, 2023
    Inventors: Ute SCHAEPER, Sibylle DAMES, Steffen SCHUBERT, Alfonso MARTÍNEZ DE LA CRUZ, Jorge SIMÓN ESPINOSA, Irene GONZALEZ RECIO, María Luz MARTÍNEZ CHANTAR
  • METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE
    Publication number: 20220026444
    Abstract: The present invention relates to a CNNM4 inhibitor for use in the treatment of an acute or a chronic liver, kidney and/or lung disease in a subject, and to pharmaceutical compositions comprising a therapeutically effective amount of a CNNM4 inhibitor and a pharmaceutically acceptable excipient or carrier. Furthermore, the invention relates to a method for diagnosing a liver disease, a kidney disease or a lung disease in a subject, and to in vitro methods for identifying a compound potentially useful for reducing an induced CNNM4-mediated disease or condition in a cell.
    Type: Application
    Filed: November 26, 2019
    Publication date: January 27, 2022
    Inventors: Jorge SIMÓN, María Luz MARTÍNEZ CHANTAR, Alfonso MARTÍNEZ DE LA CRUZ
  • METHODS AND COMPOSITIONS TO TREAT DRUG-INDUCED DISEASES AND CONDITIONS
    Publication number: 20200283770
    Abstract: Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to decrease MCJ polypeptide activity in cells, tissues, and/or subjects as a treatment for a drug-induced disease or condition are provided.
    Type: Application
    Filed: May 18, 2020
    Publication date: September 10, 2020
    Applicants: University of Vermont and State Agricultural College, Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGUNE
    Inventors: Mercedes Rincon, Maria Luz Martinez Chantar, Juan Anguita, Oliver Dienz
  • Methods and compositions to treat drug-induced diseases and conditions
    Patent number: 10655126
    Abstract: Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to decrease MCJ polypeptide activity in cells, tissues, and/or subjects as a treatment for a drug-induced disease or condition are provided.
    Type: Grant
    Filed: July 9, 2016
    Date of Patent: May 19, 2020
    Assignees: University of Vermont and State Agricultural College, Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGune
    Inventors: Mercedes Rincon, Maria Luz Martinez Chantar, Juan Anguita, Oliver Dienz
  • Methods and compositions to treat liver diseases and conditions
    Patent number: 10457941
    Abstract: Methods and compounds useful to treat diseases and conditions are provided. Methods of administering one or more microRNA-inhibitor compounds or one or more microRNA-enhancing compounds to cells, tissues, and/or subjects as a treatment for a disease or condition are provided.
    Type: Grant
    Filed: August 20, 2016
    Date of Patent: October 29, 2019
    Assignee: Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGUNE
    Inventors: Maria Luz Martinez Chantar, Juan Anguita
  • METHODS AND COMPOSITIONS TO TREAT DRUG-INDUCED DISEASES AND CONDITIONS
    Publication number: 20190078086
    Abstract: Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to decrease MCJ polypeptide activity in cells, tissues, and/or subjects as a treatment for a drug-induced disease or condition are provided.
    Type: Application
    Filed: July 9, 2016
    Publication date: March 14, 2019
    Applicants: University of Vermont and State Agricultural College, Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGUNE
    Inventors: Mercedes Rincon, Maria Luz Martinez Chantar, Juan Anguita, Oliver Dienz
  • METHODS AND COMPOSITIONS TO TREAT LIVER DISEASES AND CONDITIONS
    Publication number: 20180245080
    Abstract: Methods and compounds useful to treat diseases and conditions are provided. Methods of administering one or more microRNA-inhibitor compounds or one or more microRNA-enhancing compounds to cells, tissues, and/or subjects as a treatment for a disease or condition are provided.
    Type: Application
    Filed: August 20, 2016
    Publication date: August 30, 2018
    Applicant: Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGUNE
    Inventors: Maria Luz MARTINEZ CHANTAR, Juan ANGUITA
  • Method for the differential diagnosis of non-alcoholic fatty liver disease based on a metabolomic profile
    Patent number: 8758992
    Abstract: The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis).
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: June 24, 2014
    Assignee: One Way Liver Genomics, S.L.
    Inventors: Jonathan Barr, Azucena Castro Espido, Jose Maria Mato De La Paz, Maria Luz Martinez Chantar
  • Method for the diagnosis of non-alcoholic steatohepatitis based on a metabolomic profile
    Patent number: 8563318
    Abstract: The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis).
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: October 22, 2013
    Assignee: One Way Liver Genomics, S.L.
    Inventors: Jonathan Barr, Azucena Castro Espido, Jose Maria Mato De La Paz, Maria Luz Martinez Chantar
  • METHOD FOR THE DIAGNOSIS OF NON-ALCOHOLIC STEATOHEPATITIS BASED ON A METABOLOMIC PROFILE
    Publication number: 20120187289
    Abstract: The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis).
    Type: Application
    Filed: September 20, 2010
    Publication date: July 26, 2012
    Applicant: One Way Liver Genomics, S.L.
    Inventors: Jonathan Barr, Azucena Castro Espido, Jose Maria Mato De La Paz, Maria Luz Martinez Chantar
  • METHOD FOR THE DIAGNOSIS OF NON-ALCOHOLIC STEATOHEPATITIS BASED ON A METABOLOMIC PROFILE
    Publication number: 20110180703
    Abstract: The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis).
    Type: Application
    Filed: August 11, 2009
    Publication date: July 28, 2011
    Applicant: ONE WAY LIVER GENOMICS, S.L.
    Inventors: Jonathan Barr, Azucena Castro Espido, Jose Maria Mato De La Paz, Maria Luz Martinez Chantar