Abstract: The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) of a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grown on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytoso

Abstract: The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grow on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of

Abstract: The invention relates to a method for the preparation of a hyperbranched polyester mixture obtainable by reacting a hydroxyl group containing carboxylic acid (B) with at least one carboxylic acid group and at least two hydroxyl groups with a diol (C) having a molecular weight of more than 100 g/mol, optionally in the presence of at least one further reactant, wherein the at least one further reactant is a polyol (A) having at least three hydroxyl groups under a reaction condition allowing ester and ether formation; and reacting the mixture resulting from step (a) with a hydrophobic carboxylic acid (D) resulting in the hyperbranched polyester mixture. The invention further relates to said hyperbranched polyester mixture and the use as wax inhibitor, as pour point depressant, as lubricant or in lubricating oils.

Abstract: The present invention relates to a composition suitable for treating hair comprising a polymer selected from the group consisting of a branched polylysine and a branched polylysine in which to 80% of the amino groups present in the branched polylysine are derivatized so that they bear one or two substituents, and comprising at least one surfactant. Furthermore, the present invention relates to a branched polylysine in which 1 to 80% of the amino groups present in the branched polylysine are derivatized so that they bear one or two substituents, wherein these substituents are acyl groups having 6 to 24 C-atoms. Furthermore, the present invention relates to the use of a branched polylysine or of the branched polylysine in which amino groups are derivatized or of the said composition for treating hair.

Abstract: The present invention relates to aqueous binder compositions comprising an aqueous polymer latex of a film forming carboxylated polymer and a branched polyetheramine polyol dissolved in the aqueous phase of the aqueous polymer latex, wherein essentially all of the amino groups in the branched polyetheramine polyol are tertiary amine groups. The present invention also relates to water-borne coating compositions containing such an aqueous binder composition.

Abstract: Use of hydrophobically modified polyalkanolamines obtainable by condensing at least one trialkanolamine and optionally further condensable monomers and reacting at least one of the terminal OH groups with suitable reactants capable of reacting with OH groups and comprising long chain hydrocarbon groups as wax inhibitor, pour point depressant and additive for lubricants.

Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.

Abstract: A process for producing a polymer foam including reacting components A to C in the presence of component D and optionally E or of an isocyanate-functional prepolymer of components A and B with component C in the presence of component D and optionally E. The polymer foam includes 35 to 75 wt % of at least one polyisocyanate component A, 5 to 50 wt % of at least one polyol component B, 1 to 10 wt % of water as component C, 0.01 to 3 wt % of at least one Lewis base component D, and optionally 0 to 5 wt % of at least one foam stabilizer component E. Component A is a condensation product including polyimide groups and obtained by condensing at least one polyisocyanate component with at least one polycarboxylic acid having at least 3 COOH groups per molecule or anhydride. The process is effected to release carbon dioxide.

Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.

Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.

Abstract: The present invention relates to the preparation of ?-lactam antibodies comprising contacting 4-hydroxyphenylglycine of phenylglycine, cysteine and valine with a non-ribosomal peptide synthetase and subsequent cyclization using an isopenicillin N synthase in the presence of an MbtH-like protein and to a host cell equipped to perform such preparation.

Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.

Abstract: Provided are new partially hydrogenated nitrile rubbers which are distinguished by a specific ratio of viscosity to molecular weight, and also vulcanizable mixtures and vulcanizates based on said rubbers, and also the associated preparation processes. The partially hydrogenated nitrile rubbers lead to compounded formulations having advantageous processing properties in conjunction with excellent vulcanizate properties.

Abstract: Pursuant to the invention a process for the production of hydrogenated nitrile rubber polymers having lower molecular weights and narrower molecular weight distributions than those known in the art in the is provided wherein the process is carried out in the presence of hydrogen and optionally at least one co-(olefin). The present invention further relates to the use of specific metal compounds in a process for the production of a hydrogenated nitrile rubber by simultaneous hydrogenation and metathesis of a nitrile rubber.

Abstract: The present invention relates to a process for the production of hydrogenated nitrile rubber polymers having lower molecular weights and narrower molecular weight distributions than those known in the art, wherein the process is carried out in the presence of hydrogen and optionally at least one co-olefin. The present invention further relates to the use of specific metal compounds in a process for the production of a hydrogenated nitrile rubber by simultaneous hydrogenation and metathesis of a nitrile rubber.

Abstract: The present invention relates to the preparation of ?-lactam antibiotics comprising contacting 4-hydroxyphenylglycine or phenylglycine, cysteine and valine with a non-ribosomal peptide synthetase and subsequent cyclization using an isopenicillin N synthase in the presence of an MbtH-like protein and to a host cell equipped to perform such preparation.

Abstract: A process of degrading nitrile rubbers comprises subjecting them to a metathesis reaction in the presence of specific catalysts with increased activity.

Abstract: The present invention relates to a method of identifying a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of) a yeast cell comprising: a) providing a mutated yeast cell comprising a deletion of at least one gene of the (PDH) by-pass, selected from the genes encoding the enzymes pyruvate decarboxylase (PDC), acetaldehyde dehydrogenase (ALD), and acetyl-CoA synthetase (ACS); b) transforming said mutated yeast cell with an expression vector comprising a heterologous nucleotide sequence encoding a candidate polypeptide having potential enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA; c) testing said recombinant mutated yeast cell for its ability to grow on minimal medium containing glucose as sole carbon source, and d) identifying said candidate polypeptide as a heterologous polypeptide having enzymatic activity for converting pyruvate, acetaldehyde or acetate into acetyl-CoA in (the cytosol of

Abstract: Provided are new partially hydrogenated nitrile rubbers which are distinguished by a specific ratio of viscosity to molecular weight, and also vulcanizable mixtures and vulcanizates based on said rubbers, and also the associated preparation processes. The partially hydrogenated nitrile rubbers lead to compounded formulations having advantageous processing properties in conjunction with excellent vulcanizate properties.

Abstract: A process of degrading nitrile rubbers comprises subjecting them to a metathesis reaction in the presence of specific catalysts with increased activity.