Patents by Inventor Maria Mihaylova

Maria Mihaylova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for promoting intestinal stem cell and/or non-stem progenitor cell function
    Patent number: 10426757
    Abstract: Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful for stimulating the proliferation of and/or self-renewal of intestinal stem cells, as well as for minimizing, preventing, or ameliorating cellular damage resulting from incidental or accidental exposure to radiation (e.g., cancer radiation therapy).
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: October 1, 2019
    Assignees: Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
    Inventors: David M. Sabatini, Omer Yilmaz, Maria Mihaylova
  • COMPOSITIONS AND METHODS FOR PROMOTING INTESTINAL STEM CELL AND/OR NON-STEM PROGENITOR CELL FUNCTION
    Publication number: 20170258772
    Abstract: Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful for stimulating the proliferation of and/or self-renewal of intestinal stem cells, as well as for minimizing, preventing, or ameliorating cellular damage resulting from incidental or accidental exposure to radiation (e.g., cancer radiation therapy).
    Type: Application
    Filed: May 29, 2015
    Publication date: September 14, 2017
    Inventors: David M. Sabatini, Omer Yilmaz, Maria Mihaylova
  • ULK1 COMPOSITIONS, INHIBITORS, SCREENING AND METHODS OF USE
    Publication number: 20160289651
    Abstract: This disclosure relates to methods and compositions useful for the treatment of cancer and diseases and disorders associated with autophagy.
    Type: Application
    Filed: February 24, 2016
    Publication date: October 6, 2016
    Applicant: Salk Institute for Biological Studies
    Inventors: Reuben J. Shaw, Daniel F. Egan, Maria Mihaylova, David Shackelford
  • MODULATION OF HISTONE DEACETYLASES FOR THE TREATMENT OF METABOLIC DISEASE, METHODS AND COMPOSITIONS RELATED THERETO
    Publication number: 20140314788
    Abstract: The invention relates to methods and compositions for the modulation of glucose homeostasis and/or the treatment of metabolic diseases. In some embodiments, the invention relates to methods and compositions for the modulation of histone deacetylases. such as Class IIa histone deacetylases.
    Type: Application
    Filed: April 11, 2011
    Publication date: October 23, 2014
    Applicant: Salk Institute for Biological Studies
    Inventors: Reuben J. Shaw, Maria Mihaylova, Marc R. Montminy, Kim Ravnskjaer, Biao Wang