Abstract: A medical system includes a medical device configured to provide device-related data for evaluating the reasons for an alarm in order to trigger appropriate countermeasures. The medical device includes a set of sensors, a display, and a processor. The processor is configured to generate an alarm message in response to the alarm signal provided by the set of sensors, detect a set of machine parameters in response to generating the alarm message, generate or obtain an encoded data package representing the set of detected machine parameters in a compressed format, and generate a mixed-type alarm convolute based on the alarm signal provided by the set of sensors. The alarm convolute comprises the alarm message in a readable format and the encoded data package, and the processor is configured to issue the alarm convolute on the display.

Abstract: The present disclosure relates to a method for determining or recommending a time point for measuring a patient's pressure readings during a blood treatment session. The method encompasses monitoring the ultrafiltration rate with which the patient's blood is treated, a relative blood volume, and/or a sodium concentration or a change in any of these, for the existence of, or meeting any pre-determined criterion for the ultrafiltration, the relative blood volume, and/or the sodium concentration, or the change thereto. Furthermore, the method encompasses transmitting a signal to a blood pressure measuring device when the pre-determined criterion for the ultrafiltration rate, the relative blood volume, and/or the sodium concentration or the change thereto is met.

Abstract: The present disclosure relates to a system with a blood treatment apparatus and with a surveillance system for monitoring the occurrence of a state of a group of predetermined states, for which states it has been previously predefined or predetermined that when they occur, gloves are to be worn by the user of the blood treatment apparatus in order to avoid contaminations or carrying over of germs.

Abstract: The present disclosure relates to a method for executing a sharing enabler of a registered medical treatment machine. The registered medical treatment machine is used in a shared medical treatment system. The method comprises the method steps: Providing a registration procedure for registering the medical treatment machine in the shared medical treatment system; Receiving an initiation request for initiating a medical treatment for a patient, being registered in the shared medical treatment system; Checking whether the received initiation request is valid by receiving a confirmation signal and if yes: Unlocking the medical treatment machine in reply to the received confirmation signal for use for the patient; Operating the medical treatment machine according to a treatment procedure in a sharing mode.

Abstract: A medical system includes a medical device configured to provide device-related data for evaluating the reasons for an alarm in order to trigger appropriate countermeasures. The medical device includes a set of sensors, a display, and a processor. The processor is configured to generate an alarm message in response to the alarm signal provided by the set of sensors, detect a set of machine parameters in response to generating the alarm message, generate or obtain an encoded data package representing the set of detected machine parameters in a compressed format, and generate a mixed-type alarm convolute based on the alarm signal provided by the set of sensors. The alarm convolute comprises the alarm message in a readable format and the encoded data package, and the processor is configured to issue the alarm convolute on the display.

Abstract: The present invention relates to a tube covering for a tubing system, especially for monitoring a vascular access for an extracorporeal blood treatment. The inventive tube covering has at least one flexible bottom layer on which a section of the at least one tubing and/or a connection system of at least one tubing may be placed and has at least one flexible top layer for covering the section of the at least one tubing and/or the connection system of the at least one tubing. The bottom layer and the top layer are joined to one another such that they form an openable wrapping for inserting the section of the at least one tubing and/or the connection system of the at least one tubing, fastening means for detachably joining the top layer and the bottom layer being provided on the top layer and bottom layer.

Abstract: The present invention relates to a method and to an apparatus for predicting one or more parameters characteristic for the outcome of a blood treatment, wherein the blood treatment is a treatment in which the blood of the patient has fluid removed via at least one membrane, wherein the parameters are the allowed drinking volume, the hyperhydration or hypohydration of the patient, the clearance of large molecules and/or the allowed salt intake, wherein the prediction of the allowed drinking volume and the prediction of the hyperhydration or hypohydration are carried out on the basis of the planned weight loss due to ultrafiltration, of the drinking quantity during the treatment, of the rinseback volume and of residual diuresis data, and/or wherein the prediction of the clearance of large molecules is carried out on the basis of the urea clearance, and/or wherein the prediction of the allowed salt intake takes place based on the sodium ion quantity removed by ultrafiltration and by diffusion from the blood.

Abstract: The present invention relates to a tube covering for a tubing system, especially for monitoring a vascular access for an extracorporeal blood treatment. The inventive tube covering has at least one flexible bottom layer on which a section of the at least one tubing and/or a connection system of at least one tubing may be placed and has at least one flexible top layer for covering the section of the at least one tubing and/or the connection system of the at least one tubing. The bottom layer and the top layer are joined to one another such that they form an openable wrapping for inserting the section of the at least one tubing and/or the connection system of the at least one tubing, fastening means for detachably joining the top layer and the bottom layer being provided on the top layer and bottom layer.

Abstract: A method for priming a blood tubing set having a venous line and an arterial line whose connections at the patient side are in communication with two separate inlets of a chamber of, in particular, a bag and whose connections at the machine side are in communication with a dialyzer. The method includes the steps of parallel filling of both the venous and the arterial lines via a feed line so that priming liquid flows through both inlets into the chamber; and circulation of the priming liquid in the circuit of the lines, the dialyzer and the chamber via a pump so that one of the inlets of the chamber acts as an inlet and the other as an outlet.

Abstract: The invention relates to a method for priming a blood tubing set comprising a venous and an arterial line whose connections at the patient side are in communication with two separate inlets of a chamber of in particular a bag and whose connections at the machine side are in communication with a dialyzer comprising the steps: parallel filling of both the venous and the arterial line via a feed line so that priming liquid flows through both inlets into the chamber; and circulation of the priming liquid in the circuit of the lines, the dialyzer and the chamber via a pump so that one of the inlets of the chamber acts as an inlet and the other as an outlet. The invention likewise comprises a corresponding blood tubing set and a bag as well as methods for providing them.

Abstract: A family of compounds of formula (I) wherein: X is one of the following radicals: which behaves as dual site acetyl-cholinesterase inhibitors and which are especially useful for the treatment of cognitive disorders as senile dementia, cerebrovascular dementia, mild cognition impairment, attention deficit disorder, and/or neurodegenerative dementing disease with aberrant protein aggregations as specially Alzheimer's disease, Parkinson disease, ALS, or prion diseases, as Creutzfeldt-Jakob disease or Gerst-mann-Straussler-Scheiner disease.

Abstract: The invention provides compounds of formula: which have a tacrine moiety connected to an heterocyclic moiety through a linker. Through careful selection of the substituents and the linker, the activity and selectivity towards acetylcholinesterase can be modulated. The compounds show potent AChE inhibition activities together with modifications in the ?-amyloid aggregation properties by binding simultaneously to the catalytic and peripheral AChE sites. They are useful in the treatment of AChE mediated diseases, such as the Alzheimer's disease.